Results 161 to 170 of about 11,278 (243)

Hydrolases in organic chemistry. Recent achievements in the synthesis of pharmaceuticals [PDF]

open access: yes, 2016
Gotor Fernández, Vicente   +2 more
core   +1 more source

Deciphering Role of Endophytes in Plant Defences and Biotic Stress Resilience Across Families

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Plant families generate distinct repertoires of specialised metabolites that govern their biotic interactions. Endophytes strengthen host plant defence mechanisms and tolerance to biotic challenges by upregulating metabolite biosynthesis, modifying precursor compounds into more potent forms, or by directly synthesising analogous defence ...
S. Aneeqa Noor   +4 more
wiley   +1 more source

Biotransformation of monoterpenols upon pre‐treatment with oregano essential oil vapour alleviates downy mildew susceptibility in grapevine leaves

open access: yesPlant Biology, EarlyView.
Pre‐treatment of grapevine plants with oregano essential oil vapour alleviates downy mildew susceptibility by accumulation of monoterpenol glycosides. Abstract Grapevine downy mildew, caused by the oomycete Plasmopara viticola, is a destructive disease that causes major economic losses as most elite grapevine cultivars are susceptible to this pathogen.
J. R. P. E. Mars   +6 more
wiley   +1 more source

Baeyer-Villiger monooxygenase-catalyzed desymmetrizations of cyclobutanones. Application to the synthesis of valuable spirolactones [PDF]

open access: yes, 2016
Collado, Iván   +7 more
core   +2 more sources

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor   +4 more
wiley   +1 more source

PFAS Vadose Zone Mass Discharge at an AFFF‐Impacted Site: 1. Validation Based on a Multiple Lines‐of‐Evidence Approach

open access: yesRemediation Journal, Volume 36, Issue 2, Spring 2026.
ABSTRACT Questions have recently been raised about the suitability of using porewater samples collected with suction lysimeters to estimate per‐ and polyfluoroalkyl substances (PFAS) mass discharge in the vadose zone. Multiple lines of evidence were evaluated to determine if porewater samples collected during a data gaps investigation in the former ...
Grant R. Carey   +8 more
wiley   +1 more source

Impacts of Salinity on Growth, Physiology and Tissue Integrity of Nile Tilapia: Implications for Coastal Aquaculture Under Climate Change

open access: yesAquaculture, Fish and Fisheries, Volume 6, Issue 3, June 2026.
ABSTRACT Climate change is responsible for salinity intrusion in coastal areas, which is significantly threatening the sustainability of aquaculture. This investigation focused on evaluating growth performance, proximate composition, blood morphology and histopathological modifications in Nile tilapia (Oreochromis niloticus) exposed to varying salinity
Shakil Ahmed   +5 more
wiley   +1 more source

Equol Alleviates Postmenopausal Metabolic Dysfunction‐Associated Steatotic Liver Disease via the GPR30/PI3K Pathway

open access: yeseFood, Volume 7, Issue 3, June 2026.
This study demonstrates that equol exerts a protective effect on metabolic dysfunction‐associated steatotic liver disease in both in vivo and in vitro by activating the GPR30/PI3K/Nrf2 signaling pathway. Equol's interaction with GPR30 and its ability to activate the PI3K/Nrf2 pathway provide a promising therapeutic strategy for treating metabolic ...
Hanqiang Cui   +8 more
wiley   +1 more source

Ivermectin Toxicity in Humans and Animals: Clinical Spectrum, Mechanisms, and Management

open access: yesJournal of Applied Toxicology, Volume 46, Issue 6, Page 1856-1870, June 2026.
ABSTRACT Ivermectin is a widely used macrocyclic lactone with established efficacy against a broad range of parasitic infections in humans and animals and a long‐standing reputation for clinical safety. However, increasing evidence indicates that ivermectin can produce clinically relevant toxicity under specific conditions, particularly involving the ...
Serkan Yilmaz   +3 more
wiley   +1 more source

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