Results 181 to 190 of about 8,785 (292)

Astragaloside IV and Ferroptosis Modulation in Pathological Cardiac Hypertrophy: Current Evidence, an Integrative Hypothesis, and Future Directions

Pharmacology Research &Perspectives, Volume 14, Issue 6, December 2026.
ABSTRACT Pathological cardiac hypertrophy is initially an adaptive response to sustained mechanical, neurohormonal, or metabolic stress; however, it can progress to fibrosis, contractile dysfunction, arrhythmia, and heart failure. Ferroptosis is a type of regulated cell death caused by iron‐dependent phospholipid peroxidation.
Pengbo Liu, Yongzhi Deng
wiley   +1 more source

Systematic mass-spectrometry-guided metabolic fingerprinting elucidates diversity of specialized metabolites across the Brassicaceae. [PDF]

Metabolomics
Wolters FC, Woldu T, Schranz ME, Medema MH, Bouwmeester K, van der Hooft JJJ.   +5 more
europepmc   +1 more source

PFAS Vadose Zone Mass Discharge at an AFFF‐Impacted Site: 1. Validation Based on a Multiple Lines‐of‐Evidence Approach

Remediation Journal, Volume 36, Issue 2, Spring 2026.
ABSTRACT Questions have recently been raised about the suitability of using porewater samples collected with suction lysimeters to estimate per‐ and polyfluoroalkyl substances (PFAS) mass discharge in the vadose zone. Multiple lines of evidence were evaluated to determine if porewater samples collected during a data gaps investigation in the former ...
Grant R. Carey, David T. Adamson, Rita K. Krebs, Mia Rebeiro‐Tunstall, Kevin G. Mumford, Bo Guo, Gabriel T. Carey, Kiera Rooney, Sabrina Moga   +8 more
wiley   +1 more source

Transformation-Aware Molecular Networking for Interpretation of Untargeted LC-HRMS Data. [PDF]

ACS Meas Sci Au
Ferri E, Caprari C, Vandelli MA, Cecchi R, Verri P, Citti C, Cannazza G.   +6 more
europepmc   +1 more source

Microbial Mechanisms and Sensory Outcomes of Flavor Development in Fermented Plant‐Based Proteins

Sustainable Food Proteins, Volume 4, Issue 4, December 2026.
Fermentation improves the flavor and consumer appeal of plant‐based proteins by reducing off‐flavors and generating desirable taste and aroma compounds. This review summarizes microbial mechanisms of flavor development, factors influencing sensory quality, and emerging opportunities in precision fermentation, flavoromics, and microbial engineering ...
Nancy D. Asen
wiley   +1 more source

Hydrogen-driven, ATP-dependent biocatalytic reduction of carboxylic acids under non-explosive conditions.

Green Chem
Karava M, Liang Q, van der Pol E, Winkler M, Kourist R.   +4 more
europepmc   +1 more source

Toward Sustainable Testosterone Manufacturing: Green Chemistry and Microbial Biotransformation Approaches. [PDF]

Int J Mol Sci
Fernández-Cañón JM, Chamizo-Ampudia A.   +1 more
europepmc   +1 more source

Fragment Coverage: Unified Visualization and Quantitative Assessment of MS/MS Fragmentation Supports Metabolite Identification in Macromolecule Drug Metabolism Studies

Rapid Communications in Mass Spectrometry, Volume 40, Issue 21, 15 November 2026.
ABSTRACT Rationale Peptides and oligonucleotides are increasingly used as therapeutic agents, making the identification and structural elucidation of their metabolites a critical step in drug development. Liquid chromatography–mass spectrometry (LC‐MS/MS) is the primary analytical technique for this purpose; however, extensive backbone fragmentation ...
Paula Cifuentes, Albert Garriga, Fabien Fontaine, Ismael Zamora   +3 more
wiley   +1 more source

HaloTag-Based FACS-Compatible Assay for Intracellular Haloalkane Detection with a Potential Application to Halogenase Screening. [PDF]

Anal Chem
Meinert H, Wolfgramm H, Meier H, Somvilla I, Seifert M, Csechala LA, Böttcher D, Bayer T, Buller R, Völker U, Bornscheuer UT, Badenhorst CPS.   +11 more
europepmc   +1 more source

The Boron–Neuron Connection: The Potential of Boron‐Containing Molecules for Treating Incurable Amyotrophic Lateral Sclerosis

ChemMedChem, Volume 21, Issue 21, 12 November 2026.
Can a single element help address the multifactorial nature of ALS? Boron‐containing compounds combine responsiveness to reactive oxygen species (ROS), neuroprotective activity, and favorable pharmacological properties, offering a distinctive framework for disease modification in a complex disease like ALS.
Nitesh Sanghai, Billy Vuong, Muhammad Shaharyar K. Afridi, Sasha Leggett, Hemin Roghzai, Geoffrey K. Tranmer   +5 more
wiley   +1 more source