Results 201 to 210 of about 7,408 (290)

A Revised Model for Muscarine Biosynthesis Involving Lysine Trimethylation

Angewandte Chemie, Volume 138, Issue 24, 8 June 2026.
The fatal mushroom toxin l‐(+)‐muscarine is one of the most prominent natural products. We elucidated its biosynthetic origin in the sweating mushroom Collybia rivulosa based on incorporation of stable isotope‐labeled compounds and extensive mass spectrometric analyses.
Sebastian Dörner, Kai Rogge, Felix Trottmann, Christian Hertweck, Dirk Hoffmeister   +4 more
wiley   +2 more sources

Engineered Biocatalyst for Enantioselective Hydrazone Reduction. [PDF]

Angew Chem Int Ed Engl
Hutton AE, Zhao F, Ho E, Domenech J, Harawa V, Brown MJB, Grogan G, Clayman PD, Turner NJ, Green AP.   +9 more
europepmc   +1 more source

Semi‐Rational Engineering of Formate Dehydrogenase Reveals Loop Dynamics as a Key Determinant of Thermostability

ChemBioChem, Volume 27, Issue 11, 15 June 2026.
Semi‐rational engineering yields a thermostable Bacillus simplex formate dehydrogenase variant (Q125F) with a 25‐fold longer half‐life at 60°C and strong resistance to chemo‐inactivation. Molecular dynamics reveal enhanced π–π interactions stabilizing a flexible loop and enabling efficient NADH regeneration for robust biocatalytic detoxification ...
Rattima Boonkumkrong, Sahachat Soithongcharoen, Pitchayathida Mee‐udorn, Paweenapon Chunthaboon, Somchart Maenpuen, Thanyada Rungrotmongkol, Pratchaya Watthaisong, Ruchanok Tinikul   +7 more
wiley   +1 more source

Glycerol-supplemented medium promotes transition of Cupriavidus necator from heterotrophic to lithoautotrophic growth. [PDF]

Biotechnol Lett
Castro Gonzalez I, Gorret N, Lauterbach L, Guillouet SE.   +3 more
europepmc   +1 more source

Influence of ionic liquids on enzymatic asymmetric carboligations. [PDF]

Comput Struct Biotechnol J
Gerhards T, Harrar TE, Klein AS, Lieres EV, Paul CE, Lavandera I, Gotor-Fernández V, Pietruszka J, Pohl M, Gohlke H, Rother D.   +10 more
europepmc   +1 more source

Enantioselective electrophilic α-fluorination catalyzed by an artificial metalloenzyme. [PDF]

Chem Sci
Yu J, Wang C, Hu W, Wang H, Zhao J, Pan HJ.   +5 more
europepmc   +1 more source

Synthesis and In Vitro Metabolic Profiling of the Selective Androgen Receptor Modulator (SARM) LY305. [PDF]

Rapid Commun Mass Spectrom
Kobidze G, Möller T, Wen HC, Busardò FP, Thevis M.   +4 more
europepmc   +1 more source

Integrating Vibrio natriegens for Photon Manipulation in Living Lighting Devices

Advanced Materials, Volume 38, Issue 34, 17 June 2026.
Rationalization of genetic and material engineering tools has enabled the engineering of fluorescent Vibrio natriegens (V. natriegens) to fabricate straightforward, highly emissive and stable V. natriegens‐silicones color filters for the first red‐emitting bacteria‐hybrid light‐emitting diodes. This pinpoints V. natriegens as a high‐performance protein
Stephanie Willeit, Maurice Hädrich, Philippe‐Quentin Liss, Valeria Rodriguez Espinoza, Nicklas Maximilian Foerster, Bastian Blombach, Rubén D. Costa   +6 more
wiley   +1 more source

In vitro metabolism of Benzyl-4CN-BUTINACA and MDMB-4CN-BUTINACA using human hepatocytes and LC-QToF-MS analysis. [PDF]

Arch Toxicol
Norman C, Webling K, Štālberga D, Maas L, Tveit J, Liu H, Watanabe S, Vikingsson S, Green H.   +8 more
europepmc   +1 more source