Results 21 to 30 of about 7,408 (290)
Crystal structure of 1-tosyl-1,2,3,4-tetrahydroquinoline
Acta Crystallographica Section E, 2014 In the title compound, C16H17NO2S, the heterocyclic ring adopts a half-chair conformation and the bond-angle sum at the N atom is 350.2°. The dihedral angle between the planes of the aromatic rings is 47.74 (10)°.
S. Jeyaseelan +4 more
doaj +1 more source
Unlocking a Nitrosuccinate Lyase for Decarboxylative Enzymatic Hydronitration
Angewandte Chemie, EarlyView.The nitrosuccinate lyase CreD catalyzes C–NO2 bond formation using nitrite in water and shows synthetic practicality with high turnover numbers up to 102,000. A combination of protein engineering and computational methods helped to reveal the mechanistic principles that underpin this unique enzymatic activity.
Matteo Aleotti +9 more
wiley +2 more sources
Dip Hopping Technique and Yeast Biotransformations in Craft Beer Productions
Fermentation, 2023 This paper evaluates the effects of an alternative hopping technique, called dip hopping, on beer. This technique involves infusing hops in hot water (or in a portion of wort) and subsequently combining the infusion with the wort (after wort cooling ...
Paolo Passaghe +4 more
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Clinical Pharmacology & Therapeutics, 2014 The field of clinical pharmacology and therapeutics spans a wide spectrum of research areas involving human subjects at both individual and population levels. One of the key concepts relevant to all of these research areas is biotransformation of drug molecules, which can be defined as the chemical modification of drugs within an organism.
openaire +3 more sources
Microorganisms, 2021 Microalgae and cyanobacteria are good sources for prospecting metabolites of biotechnological interest, including glucosidase inhibitors. These inhibitors act on enzymes related to various biochemical processes; they are involved in metabolic diseases ...
Diana Gomes Gradíssimo +7 more
doaj +1 more source
MoleculesThe aim of this study was to obtain new halolactones with a gem-dimethyl group in the cyclohexane ring (at the C-3 or C-5 carbon) and a methyl group in the lactone ring and then subject them to biotransformations using filamentous fungi.
Małgorzata Grabarczyk +6 more
doaj +1 more source
Chemical diversity through biotransformations
, 2004 Diversity constitutes an intrinsic property of biosynthesis. This inherent property can be exploited and successfully applied in organic synthesis. Recent advances have been made in many areas, including the use of multifunctional enzymes and catalytic ...
Müller, Michael, Müller, M.
core +1 more source
Beilstein Journal of Organic Chemistry, 2012 The hydroxylation of n-alkanes, which proceeds in the presence of a P450-monooxygenase advantageously at temperatures significantly below room temperature, is described.
Svenja Staudt +6 more
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Biocatalysis and Flow Chemistry: Artificial Cell Factories
CHIMIA, 2020 Our research focusses on highly sustainable enzymatic methods for the preparation of valuable molecules, spanning from pharmaceuticals, to small chiral intermediates, to flavours and perfumes.
Francesca Paradisi
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Advanced Science, EarlyView.Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu +18 more
wiley +1 more source