Results 41 to 50 of about 8,785 (292)

Sunscreen‐Inspired Nano‐Pesticide for UV‐Shielding and Laccase‐Responsive Delivery of Mancozeb With Enhanced Fungicidal Efficacy and Ecological Safety

Advanced Science, EarlyView.
The sunscreen‐inspired nano‐pesticide, MCB@URFSL, provides UV‐shielding, enhanced rainfastness, and laccase‐responsive delivery for improved fungicidal efficacy and high ecological safety. ABSTRACT Fungicides are a crucial tool for protecting crops and ensuring consistent food supply.
Jin Yan, Xin Ye, Linping He, Cheng Hong, Xu‐Huan Zhao, Gizachew Mulugeta Manahelohe, Xiao‐Tong Feng, Yu‐Cheng Gu, Qiang Bian, Min Wu, Ming‐Zhi Zhang   +10 more
wiley   +1 more source

Efficient Synthesis of Steroidal Intermediates with a C17 Side Chain from Phytosterols by Genetically Modified Mycolicibacterium neoaurum NRRL B‐3805 Strain

ChemistryOpen
22‐Hydroxy‐23,24‐bisnorchol‐4‐ene‐3‐one (4‐HBC) and 3‐oxo‐4,17‐pregnadiene‐20‐carboxylic acid methyl ester (PDCE) are useful precursors for the synthesis of steroidal active pharmaceutical ingredients.
Xuemei Li, Liangyan Zhu, Qiong Wu, Rui Zhang, Yiyin Liu, Na Liu, Jinhui Feng, Qiaqing Wu, Dunming Zhu   +8 more
doaj   +1 more source

Robots and Minimal, Physics‐Informed Features: A Hybrid Framework for Enzyme Catalysis

Advanced Science, EarlyView.
Robotic experimentation and physics‐informed machine learning combine to predict enzyme substrate scope. With a handful of interpretable features derived from docking and quantum mechanics calculations, our model rivals descriptor‐heavy AI approaches and extrapolates to unseen substrates and enzyme classes.
Natalia Onishchenko, Eric S. Larsen, Govind Paneru, Kisung Lee, Diana V. Kolygina, Yankai Jia, Elizabeth Maria Clarissa, Wai‐Shing Wong, Bartosz A. Grzybowski   +8 more
wiley   +1 more source

Collagenase - alone or in combination for the preparation of hepatocytes? The effect on phase 1 and phase 2 biotransformations

, 2007
Objective: To investigate the effect of digestion enzymes on metabolic biotransformations in suspensions of isolated rat hepatocytes. Isolated rat hepatocytes are a valuable whole cell in vitro tool for drug metabolism and toxicity studies.
Grant, M.H., Martin, I.J., Sinclair, J.A., Tettey, J.N.A., Henderson, C.J.   +4 more
core   +3 more sources

Glycosylation of 3-Hydroxyflavone, 3-Methoxyflavone, Quercetin and Baicalein in Fungal Cultures of the Genus Isaria

Molecules, 2018
Flavonoids are plant secondary metabolites with a broad spectrum of biological activities. In nature, they occur mainly in the form of glycosides, but their extraction is often difficult and expensive, as is chemical synthesis.
Monika Dymarska, Tomasz Janeczko, Edyta Kostrzewa-Susłow   +2 more
doaj   +1 more source

Biotransformations on steroid nucleus of bile acids

, 1997
The bile acids in mammals are all derivatives of 5β-cholan-26-oic acid. They represent the major quantitative pathway by which cholesterol is metabolized in the body. This article covers the microbial and enzymatic transformations of free, saturated bile
MEDICI, Alessandro, BORTOLINI, Olga, S. Poli, Silvia Poli, Olga Bortolini, Alessandro Medici   +5 more
core   +1 more source

Chiral biotransformations of cyclic nitrile compounds [PDF]

, 2023
The aim of this thesis was to improve the understanding of how bacteria (in particular Rhodococcus rhodochrous LL100-21) use enzymatic reactions to biotransform nitrile compounds.

core   +1 more source

Metabolic‐Redox Remodeling of Inflammatory Synovium by Mannose‐Modified Selenium Nanoparticles for Osteoarthritis Therapy

Advanced Science, EarlyView.
Elevated GLUT1‐driven glycolysis and disrupted selenoprotein‐dependent redox homeostasis drive osteoarthritic progression. Intra‐articular mannose‐modified selenium nanoparticles (M‐SeNPs) selectively target hypermetabolic synovial cells to reprogram aberrant glycolysis and restore endogenous antioxidant defenses.
Yu‐Qing Zou, Chen‐Hao Xu, Bo‐Wei Li, Leung Chan, Yi‐Di Xu, Han‐Bo Su, Rui Peng, Fang‐Ji Luo, Ya‐Chen Peng, Zhen‐Yan Li, Vincent Kam Wai Wong, Xiao‐Fei Zheng, Xing Ma, Zhen‐Gang Zha, Tianfeng Chen, Huan‐Tian Zhang   +15 more
wiley   +1 more source

Resolution of Racemic Acids, Esters and Amines by Candida rugosa Lipase in Slightly Hydrated Organic Media

Food Technology and Biotechnology, 2004
Commercial crude lipase from Candida rugosa is widely used as a biocatalyst in the resolution of racemic mixtures and in organic synthesis in slightly hydrated organic solvents.
Andrés R. Alcántara, Pablo Domínguez de María, María Fernández, María José Hernaíz, José María Sánchez-Montero, José Vincente Sinisterra   +5 more
doaj  

Recent Applications of Albumin as a Green and Versatile Catalyst in Organic Synthesis

Molecules
Today, biocatalytic methodologies are well established as useful tools in green organic synthesis, since biocatalysts are mild, sustainable, and environmentally friendly catalysts which provide selectivity to the reactions they catalyse.
Estefanía L. Borucki, Luis E. Iglesias
doaj   +1 more source