Results 51 to 60 of about 11,278 (243)

H-2-driven biotransformation of n-octane to 1-octanol by a recombinant Pseudomonas putida strain co-synthesizing an O-2-tolerant hydrogenase and a P450 monooxygenase [PDF]

, 2015
An in vivo biotransformation system is presented that affords the hydroxylation of n-octane to 1-octanol on the basis of NADH-dependent CYP153A monooxygenase and NAD(+)-reducing hydrogenase heterologously synthesized in a bacterial host.
Hauer, Bernhard, Lauterbach, Lars, Lenz, Oliver, Lonsdale, Thomas H., Malca, Sumire Honda, Nestl, Bettina M.   +5 more
core   +1 more source

Drug‐Induced Cuproptosis Defines the Therapeutic Window of Celecoxib in Intervertebral Disc Degeneration via the HSP90‐RBX1 Axis

Advanced Science, EarlyView.
This study reveals the dual role of celecoxib in intervertebral disc degeneration. While low concentrations are protective, high concentrations induce toxicity by upregulating HSP90, which synergizes with USP15 to deubiquitinate and stabilize RBX1. This leads to degradation of COMMD1/ATP7B, copper dyshomeostasis, and ultimately, cuproptosis.
Youfeng Guo, Hongju Xiao, Shenghao Ba, Yu Zhou, Bijun Wang, Bin Yu, Yufeng Huang, Haihong Zhao, Zhefan Stephen Chen, Na Shen, Zhaoyu Ba, Desheng Wu   +11 more
wiley   +1 more source

Turning Mushy Lipids into Fruity Notes: Unlocking Lactone Biosynthesis Potential in Fat Industry Lipid Waste

Foods
Waste from the fat-processing industry represents a challenging stream due to its physicochemical properties and environmental impact. Valorization through recovery and reuse offers ecological, economic, and social benefits.
Jolanta Małajowicz, Katarzyna Wierzchowska, Karina Jasińska, Agata Fabiszewska   +3 more
doaj   +1 more source

Preparation and characterization of protein-nanotube conjugates [PDF]

, 2009
This chapter describes methods of immobilizing proteins on carbon nanotubes, using two different routes—physical adsorption and covalent attachment.
Asuri, Prashanth, Bale, Shyam Sundhar, Banerjee, Akhilesh, Dordick, Jonathan S., Joshi, Amit, Kane, Ravi S., Pangule, Ravindra C., Shah, Dhiral A., Vance, David   +8 more
core   +1 more source

Fermented Citrus as a Functional Food Matrix: Evaluating Probiotic, Prebiotic, and Postbiotic Potential

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Fermented citrus transforms bioactive compounds into metabolites with probiotic and prebiotic properties, enhancing gut health, immunity, and metabolic balance. This review highlights fermentation's role in developing sustainable, health‐promoting functional foods while addressing challenges in process optimization, sensory quality, and commercial ...
Sony Kumari, Rahel Debbarma, Shakil Haque, Himalay Baruah   +3 more
wiley   +1 more source

Efficient Synthesis of Steroidal Intermediates with a C17 Side Chain from Phytosterols by Genetically Modified Mycolicibacterium neoaurum NRRL B‐3805 Strain

ChemistryOpen
22‐Hydroxy‐23,24‐bisnorchol‐4‐ene‐3‐one (4‐HBC) and 3‐oxo‐4,17‐pregnadiene‐20‐carboxylic acid methyl ester (PDCE) are useful precursors for the synthesis of steroidal active pharmaceutical ingredients.
Xuemei Li, Liangyan Zhu, Qiong Wu, Rui Zhang, Yiyin Liu, Na Liu, Jinhui Feng, Qiaqing Wu, Dunming Zhu   +8 more
doaj   +1 more source

Glycosylation of 3-Hydroxyflavone, 3-Methoxyflavone, Quercetin and Baicalein in Fungal Cultures of the Genus Isaria

Molecules, 2018
Flavonoids are plant secondary metabolites with a broad spectrum of biological activities. In nature, they occur mainly in the form of glycosides, but their extraction is often difficult and expensive, as is chemical synthesis.
Monika Dymarska, Tomasz Janeczko, Edyta Kostrzewa-Susłow   +2 more
doaj   +1 more source

Resolution of Racemic Acids, Esters and Amines by Candida rugosa Lipase in Slightly Hydrated Organic Media

Food Technology and Biotechnology, 2004
Commercial crude lipase from Candida rugosa is widely used as a biocatalyst in the resolution of racemic mixtures and in organic synthesis in slightly hydrated organic solvents.
Andrés R. Alcántara, Pablo Domínguez de María, María Fernández, María José Hernaíz, José María Sánchez-Montero, José Vincente Sinisterra   +5 more
doaj  

Recent Applications of Albumin as a Green and Versatile Catalyst in Organic Synthesis

Molecules
Today, biocatalytic methodologies are well established as useful tools in green organic synthesis, since biocatalysts are mild, sustainable, and environmentally friendly catalysts which provide selectivity to the reactions they catalyse.
Estefanía L. Borucki, Luis E. Iglesias
doaj   +1 more source

Evolutionary Relationships Between the Laccase Genes of Polyporales: Orthology-Based Classification of Laccase Isozymes and Functional Insight From Trametes hirsuta

Frontiers in Microbiology, 2019
Laccase is one of the oldest known and intensively studied fungal enzymes capable of oxidizing recalcitrant lignin-resembling phenolic compounds. It is currently well established that fungal genomes almost always contain several non-allelic copies of ...
Olga S. Savinova, Konstantin V. Moiseenko, Ekaterina A. Vavilova, Andrey M. Chulkin, Tatiana V. Fedorova, Tatiana V. Tyazhelova, Daria V. Vasina   +6 more
doaj   +1 more source