Results 31 to 40 of about 8,785 (292)

Microbial Modifications of Androstane and Androstene Steroids by Penicillium vinaceum

Molecules, 2020
The biotransformation of steroid compounds is a promising, environmentally friendly route to new pharmaceuticals and hormones. One of the reaction types common in the metabolic fate of steroids is Baeyer-Villiger oxidation, which in the case of cyclic ...
Anna Panek, Paulina Łyczko, Alina Świzdor   +2 more
doaj   +1 more source

Daily Monitoring at a Full-Scale Wastewater Treatment Plant Reveals Temporally Variable Micropollutant Biotransformations

, 2023
Despite decades of micropollutant (MP) monitoring at wastewater treatment plants (WWTPs), we lack a fundamental understanding of the time-varying metabolic processes driving MP biotransformations.
Damian E. Helbling (1712503), Stephanie L. Rich (11872847)   +1 more
core   +1 more source

Printed Integrated Logic Circuits Based on Chitosan‐Gated Organic Transistors for Future Edible Systems

Advanced Functional Materials, EarlyView.
Edible electronics needs integrated logic circuits for computation and control. This work presents a potentially edible printed chitosan‐gated transistor with a design optimized for integration in circuits. Its implementation in integrated logic gates and circuits operating at low voltage (0.7 V) is demonstrated, as well as the compatibility with an ...
Giulia Coco, Valerio Francesco Annese, Valerio Galli, Ilaria Penna, Debora Russo, Marina Veronesi, Rita Scarpelli, Stefania Sabella, Mario Caironi   +8 more
wiley   +1 more source

Microbial Transformation of Sesquiterpenoids

Natural Product Communications, 2009
Biotransformations are useful methods for producing medicinal and agricultural chemicals from both active and inactive natural products with the introduction of chemical functions into remote sites of the molecules.
Haq N Bhatti, Muhammad Zubair, Nasir Rasool, Zahid Hassan, Viqar U Ahmad   +4 more
doaj   +1 more source

Dramatic Enhancement of Enantioselectivity of Biotransformations of β-Hydroxy Nitriles Using a Simple O-Benzyl Protection/Docking Group

, 2016
Catalyzed by the Rhodococcus erythropolis AJ270 whole cell catalyst, the O-benzylated β-hydroxy alkanenitriles underwent remarkably high enantioselective biotransformations, whereas the biotransformations of free β-hydroxy alkanenitriles gave very low ...
Da-You Ma (2435959), De-Xian Wang (536988), Mei-Xiang Wang (536990), Qi-Yu Zheng (1282482)   +3 more
core   +1 more source

Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer

Advanced Science, EarlyView.
The mechanisms of SeNPs therapy in cancer treatment, encompass three parallel actions: (1) seleno‐amino acids, key metabolites, upregulate GPX2 expression, thereby inhibiting tumor metastasis via the GPX2‐HIF1α‐VEGF signaling pathway; (2) selenite (SeO32−), an inorganic metabolite, forms hydrogen bonds with amino acid residues 13–17 of the KRAS G13D ...
Xiaoting Liu, Chong Wu, Shiyao Song, Li Ma, Shaoqing Huang, Yuting He, Qinghai Li, Yanzhou Chang, Dan Jiang, Yong Mei, Junchao Cai, Zhenshuang Du, Tianfeng Chen, Weiling He   +13 more
wiley   +1 more source

Turning Mushy Lipids into Fruity Notes: Unlocking Lactone Biosynthesis Potential in Fat Industry Lipid Waste

Foods
Waste from the fat-processing industry represents a challenging stream due to its physicochemical properties and environmental impact. Valorization through recovery and reuse offers ecological, economic, and social benefits.
Jolanta Małajowicz, Katarzyna Wierzchowska, Karina Jasińska, Agata Fabiszewska   +3 more
doaj   +1 more source

Modeling of interactions between xenobiotics and cytochrome P450 (CYP) enzymes

Frontiers in Pharmacology, 2015
The adverse effects to humans and environment of only few chemicals are well known. Absorption, distribution, metabolism and excretion (ADME) are the steps of pharmaco/toxicokinetics that determine the internal dose of chemicals to which the organism is ...
Hannu eRaunio
doaj   +1 more source

Δ1-Dehydrogenation and C20 Reduction of Cortisone and Hydrocortisone Catalyzed by Rhodococcus Strains

Molecules, 2020
Prednisone and prednisolone are steroids widely used as anti-inflammatory drugs. Development of the pharmaceutical industry is currently aimed at introducing biotechnological processes and replacing multiple-stage chemical syntheses.
Stefania Costa, Federico Zappaterra, Daniela Summa, Bruno Semeraro, Giancarlo Fantin   +4 more
doaj   +1 more source

Oxidative biotransformations using oxygenases.

, 2002
Considerable progress has been made in manipulating oxidative biotransformations using oxygenases. Substrate acceptance, catalytic activity, regioselectivity and stereoselectivity have been improved significantly by substrate engineering, enzyme ...
van Beilen JB, Schmid A, Li Z, Griengl H, de Raadt A, Witholt B, Duetz WA   +6 more
core   +1 more source