Results 21 to 30 of about 956 (195)

Old and new damage‐associated molecular patterns (DAMPs) in autoimmune diseases

Rheumatology &Autoimmunity, Volume 2, Issue 4, Page 185-197, December 2022., 2022
A perspective of novel damage‐associated molecular patterns (DAMPs), including farnesyl pyrophosphate (FPP) and GGPP, to explore the role of the mevalonate pathway and DAMPs in autoimmune diseases. Abstract All organisms living in complex environments have evolved effective mechanisms of dynamic responses to extracellular stimuli.
Na Kang, Xiaohang Liu, Kabeer Haneef, Wanli Liu   +3 more
wiley   +1 more source

Surgical Aspects of Primary Hyperparathyroidism

Journal of Bone and Mineral Research, Volume 37, Issue 11, Page 2373-2390, November 2022., 2022
ABSTRACT Parathyroidectomy (PTX) is the treatment of choice for symptomatic primary hyperparathyroidism (PHPT). It is also the treatment of choice in asymptomatic PHPT with evidence for target organ involvement. This review updates surgical aspects of PHPT and proposes the following definitions based on international expert consensus: selective PTX ...
Nancy Perrier, Brian H. Lang, Leonardo Costa Bandeira Farias, Leyre Lorente Poch, Mark Sywak, Martin Almquist, Menno R. Vriens, Michael W. Yeh, Omair Shariq, Quan‐Yang Duh, Randy Yeh, Thinh Vu, Virginia LiVolsi, Antonio Sitges‐Serra   +13 more
wiley   +1 more source

TamaFlex™—A novel nutraceutical blend improves lameness and joint functions in working horses

Veterinary Medicine and Science, Volume 8, Issue 5, Page 1936-1945, September 2022., 2022
TamaFlex™ (NXT15906F6) is a safe, efficacious, anti‐inflammatory botanical compound that alleviates symptoms of lameness in horses. NXT15906F6 also significantly reduces the proinflammatory mediators IL‐1β and TNF‐α. TamaFlex™ promotes quality of life, relieves lameness and joint discomfort and improves gait during walking and trotting in equines ...
Sandesh Jain, Satyajit G. Patil, Gopichand Chinta, KrishnaRaju Venkata Alluri   +3 more
wiley   +1 more source

How surface coatings on titanium implants affect keratinized tissue: A systematic review

Journal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 110, Issue 7, Page 1713-1723, July 2022., 2022
Abstract Apart from osseointegration, the stability and long‐term survival of percutaneous titanium implants is also strongly dependent on a qualitative soft‐tissue integration in the transcutaneous region. A firm connective tissue seal is needed to minimize soft‐tissue dehiscence and epithelial downgrowth.
Casper E. Van den Borre, Brandaan G. R. Zigterman, Maurice Y. Mommaerts, Annabel Braem   +3 more
wiley   +1 more source

Targeting Strategies for Aberrant Lipid Metabolism Reprogramming and the Immune Microenvironment in Esophageal Cancer: A Review

Journal of Oncology, Volume 2022, Issue 1, 2022., 2022
Esophageal cancer is of high importance to occurrence, development, and treatment resistance. As evidenced by recent studies, pathways (e.g., Wnt/β‐catenin, AMPK, and Hippo) are critical to the proliferation, differentiation, and self‐renewal of esophageal cancer.
Meng-Ying Cui, Xing Yi, Zhen-Zhen Cao, Dan-Xia Zhu, Jun Wu, Achuthan Chathrattil Raghavamenon   +5 more
wiley   +1 more source

History of extracardiac/cardiac events in cardiac amyloidosis: prevalence and time from initial onset to diagnosis

ESC Heart Failure, Volume 8, Issue 6, Page 5501-5512, December 2021., 2021
Abstract Aims Cardiac amyloidosis (CA) has a poor prognosis which is aggravated by diagnostic delay. Amyloidosis extracardiac and cardiac events (AECE and ACE) may help improve CA diagnosis and typing. The aim of this study was to compare AECE and ACE between different CA types and assess their relationship with survival.
Mounira Kharoubi, Mélanie Bézard, Arnault Galat, Fabien Le Bras, Elsa Poullot, Valérie Molinier‐Frenkel, Pascale Fanen, Benoit Funalot, Anissa Moktefi, Jean‐Pascal Lefaucheur, Mukedaisi Abulizi, Jean‐François Deux, François Lemonnier, Soulef Guendouz, Coraline Chalard, Amira Zaroui, Vincent Audard, Emilie Bequignon, Diane Bodez, Emmanuel Itti, Luc Hittinger, Etienne Audureau, Emmanuel Teiger, Silvia Oghina, Thibaud Damy   +24 more
wiley   +1 more source

Overview on postmenopausal osteoporosis and periodontitis: The therapeutic potential of phytoestrogens against alveolar bone loss

Frontiers in Pharmacology, 2023
Osteoporosis and periodontitis are two major chronic diseases of postmenopausal women. The association between these two diseases are evident through systemic bone loss and alveolar bone loss.
Putri Ayu Jayusman, Nurrul Shaqinah Nasruddin, Badiah Baharin, Nurul ‘Izzah Ibrahim, Haryati Ahmad Hairi, Ahmad Nazrun Shuid   +5 more
doaj   +1 more source

Drug Delivery From Polymer-Based Nanopharmaceuticals—An Experimental Study Complemented by Simulations of Selected Diffusion Processes

Frontiers in Bioengineering and Biotechnology, 2019
The success of medical therapy depends on the correct amount and the appropriate delivery of the required drugs for treatment. By using biodegradable polymers a drug delivery over a time span of weeks or even months is made possible.
Innocent J. Macha, Innocent J. Macha, Besim Ben-Nissan, Elena N. Vilchevskaya, Anna S. Morozova, Bilen Emek Abali, Wolfgang H. Müller, W. Rickert   +7 more
doaj   +1 more source

Parathyroid Hormone is Negatively Correlated with Glycated Hemoglobin in Newly Diagnosed Type 2 Diabetic Patients. [PDF]

Int J Endocrinol
Objective. The growing evidence shows that parathyroid hormone (PTH) may affect glucose metabolism. However, the relationship between them is still controversial among diabetic patients. The current study aimed to investigate the relationship between PTH and glucose metabolism in the patients with newly diagnosed type 2 diabetes (T2D). Methods. A total
He X, Liu M, Ding X, Bian N, Wang J, Wang G, Liu J.   +6 more
europepmc   +2 more sources

Treatment of calcinosis with biphosphonates in juvenile dermatomyositis [PDF]

Pediatric Rheumatology, 2008
Juvenile dermatomyositis (JDM) is a multisystem disease that is characterized by nonsuppurative inflammation of striated muscle and skin. Dystrophic calcification occurs in up to 40% of children We present our treatment approach in four JDM patients with calcinosis.
Bilginer, Y, Topaloglu, R, Gonc, N
openaire   +3 more sources