Results 151 to 160 of about 785,590 (233)

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Potential Impact of Childhood Abuse on Quality of Life During Mood-Stabilising Treatment in Individuals Living With Bipolar Disorder. [PDF]

Bipolar Disord
Wrobel AL, Dean OM, Lotfaliany M, Berk M, Sylvia LG, Thase ME, Deckersbach T, Tohen M, McInnis MG, Kocsis JH, Shelton RC, McElroy SL, Turner A, Nierenberg AA.   +13 more
europepmc   +1 more source

Mechanoadaptation via Myosin Cytoplasmic Redistribution Protects Circulating Tumor Cells From Shear‐induced Death During Hematogenous Dissemination

Advanced Science, EarlyView.
This study investigates how CTCs survive varying shear stress during hematogenous metastasis. We uncover a self‐protection mechanism, by which non‐adherent CTCs adapt to high shearing milieu through accumulated cytoplasmic myosin‐mediated disruption of myosin‐actin binding, attenuating force transmission into chromatin to protect CTCs from shear ...
Cunyu Zhang, Qianchun Wang, Keming Li, Guanshuo Hu, Ying Xin, Kai Tang, Bing Hu, Pengyu Du, Renwei Mao, Baohua Ji, Youhua Tan   +10 more
wiley   +1 more source

Psychiatric comorbidity in DiGeorge association: Suicidal ideation and bipolar disorder. [PDF]

J Mood Anxiety Disord
Nakhamiyayev R, Perry M, Sood S, Kamboj S, Khodra E, Agada B.   +5 more
europepmc   +1 more source

Design of Optical Transducer for Recognition of Biomolecular Interactions between Bacterial Lipopolysaccharides and Amino Acids

Advanced Science, EarlyView.
A deep comprehension of biomolecular phenomena at interfaces is significant with their fundamental and practical importance. Our experimental and theoretical investigations reveal that specific amino acids (glutamic acid and aspartic acid) exhibit an orientational coupling with liquid crystals, which can recognize and optically report the interfacial ...
Yena Choi, Sangmin Lee, Jin‐Kang Choi, Hyunsoo Han, Yeongseon Choi, Jun‐Hyung Im, Hyein Kim, Sangmin Jeon, Minjae Lee, Chang Yun Son, Young‐Ki Kim   +10 more
wiley   +1 more source

Open-label randomised controlled trial of aripiprazole/sertraline combination in comparison with quetiapine for the clinical and cost-effectiveness of treatment of bipolar depression (the ASCEnD study): study protocol. [PDF]

BMJ Open
Azim L, Al-Ashmori S, Butcher C, Cipriani A, Chew-Graham CA, Clare E, Clark E, Cole M, Carella S, Dixon L, Evans J, Gergel T, Gibson J, Hancock HC, Hoppe I, Kessler D, Kabir T, Lewis G, Mathias A, Morris R, Nixon N, Simon J, Teare MD, Lived Experience Advisory Panel, Wahba M, Wall L, Walmsley Z, Wienand D, Wolstenhulme F, Ahuja N, Watson S.   +30 more
europepmc   +1 more source

The Faraday Scalpel: Electrochemical Nerve Lesioning Mechanisms Studied in Invertebrate Models

Advanced Science, EarlyView.
Direct‐current produces nerve lesioning through discrete electrochemical reactions. Using hypoxia‐sensitive locust nerves and hypoxia‐tolerant leech nerves, we map three injury pathways: cathodic oxygen reduction, cathodic alkalization, and anodic chloride oxidation. These findings establish electrochemical lesioning—the “Faraday Scalpel”—as a precise,
Petra Ondráčková, Jan Švec, Marie Jakešová, Jiří Ehlich, Imrich Gablech, Eric Daniel Głowacki   +5 more
wiley   +1 more source

Mapping System-Assisted Bipolar Radiofrequency Ablation for the Treatment of Ventricular Tachycardia Associated With Ventricular Aneurysm. [PDF]

JACC Case Rep
Kong X, Gao M, Gu C, Li H, Yu Y.
europepmc   +1 more source

Scalable Electrochemical Concrete Fabrication and Closed‐Loop Recycling

Advanced Science, EarlyView.
The electrochemical‐driven recycling strategy establishes a reversible concrete material flow by extracting Ca, Si, Al, and Fe from concrete waste and regenerating functional feedstocks. These reversed products are reassembled into new concrete, which re‐enters service and ultimately returns to waste, enabling a closed‐loop, waste‐origin, and low ...
Hanxiong Lyu, Zhenlin Li, Yang Liu, Lu Zhu, Lucen Hao, Mingxin Shi, Shipeng Zhang, Chi Sun Poon   +7 more
wiley   +1 more source

Ion Crowding Effect in Unilaterally Downsized Perovskite Memristors

Advanced Science, EarlyView.
The downscaling of perovskite memristors incorporating monocrystalline nanoplates is accompanied by an ion crowding effect, which greatly enhances the local electric field in the vicinity of electrode. The highly controlled crowding of anions and vacancies results in anisotropic switching characteristics as well as unique morphology modification ...
Conghui Tan, Meiqi An, Weili Liu, Haotian Wang, Shuai Yang, Jing Li, Jianliang Li, Yingmin Luo, Chao Wang, Jiao Xu, Yaodan Chi, Yiming Yang   +11 more
wiley   +1 more source