Results 121 to 130 of about 87,187 (276)

Is Poor Lithium Response in Individuals with Bipolar Disorder Associated with Increased Degradation of Tryptophan along the Kynurenine Pathway? Results of an Exploratory Study [PDF]

open access: gold, 2022
Frederike T. Fellendorf   +21 more
openalex   +1 more source

Adenylyl Cyclase 8 in Dorsal CA1 Neurons Prevents Depressive‐Like Behaviors by Maintaining Neuronal Excitability and Glutamatergic Neurotransmission Through TIP39‐PTH2R Signaling

open access: yesAdvanced Science, EarlyView.
Depression, a prevalent neuropsychiatric disorder with unclear pathogenesis, involves dysfunctional adenylyl cyclase 8 (Adcy8) as a key risk factor. Chronic stress selectively reduces Adcy8 expression in the dorsal CA1 (dCA1) neurons. Depletion of Adcy8 in dCA1 excitatory neurons induces depressive‐like behaviors by impairing neuronal excitability and ...
Zi‐Jie Liu   +14 more
wiley   +1 more source

A 37.5-kW point design comparison of the nickel-cadmium battery, bipolar nickel-hydrogen battery, and regenerative hydrogen-oxygen fuel cell energy storage subsystems for low Earth orbit [PDF]

open access: yes
Nickel-cadmium batteries, bipolar nickel-hydrogen batteries, and regenerative fuel cell storage subsystems were evaluated for use as the storage subsystem in a 37.5 kW power system for space station.
Hoberecht, M. A., Manzo, M. A.
core   +1 more source

Palmitoylation‐Mediated Ubiquitination of SRPK1 Regulates Ferroptosis in High‐Fat‐Induced Erectile Dysfunction

open access: yesAdvanced Science, EarlyView.
Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan   +11 more
wiley   +1 more source

The Role of Ionic Liquids at the Biological Interfaces in Bioelectronics

open access: yesAdvanced Science, EarlyView.
Ionic liquids (ILs) are highlighted as key artificial ionic materials that bridge biological ion‐based signaling and electronic devices. By understanding their composition, structure, function relationships, and mechanisms, ILs can advance from high performance electrolyte to core materials enabling integrated, multifunctional bioelectronics for ...
Yeong‐sinn Ye   +5 more
wiley   +1 more source

Recent development in degradation mechanisms of proton exchange membrane fuel cells for vehicle applications: problems, progress, and perspectives

open access: yesEnergy Storage and Saving
Due to its zero emissions, high efficiency and low noise, proton exchange membrane fuel cell (PEMFC) is full of potential for the application of vehicle power source.
Zikuo Liu   +3 more
doaj   +1 more source

Radiation and shielding study for the International Ultraviolet Explorer [PDF]

open access: yes
Technical advisory services to ensure integrity of parts and material exposed to energetic particle radiation for the IUE scientific instruments, spacecraft, and subsystems are provided.
Baze, M.   +6 more
core   +1 more source

NuSAP Safeguards Centriole Integrity to Mediate CEP57‐CEP152 Torus Recruitment for Proper Engagement

open access: yesAdvanced Science, EarlyView.
This study reveals a novel role for the microtubule stabilizer NuSAP at centrioles. NuSAP depletion destabilizes the centriole's tubulin structure, causing premature disengagement, PCM defects, and mis‐localization of the CEP57‐CEP63‐CEP152 complex. By reinforcing centriole architecture, NuSAP enables early CEP57 loading and initiates a newly proposed ...
Shiyu Zhang   +8 more
wiley   +1 more source

Gallium Nitride Semiconductor Resonant Tunneling Transistor

open access: yesAdvanced Science, EarlyView.
Three‐terminal GaN semiconductor resonant tunneling transistors (RTTs), which comprise an double‐barrier AlN/GaN/AlN resonant tunneling diode integrated with a GaN high‐electron‐mobility transistor (HEMT) through epitaxial growth in series and parallel configuraions, respectively.
Fang Liu   +15 more
wiley   +1 more source

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