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Bipolar disorder is characterized by (hypo)manic episodes and depressive episodes which alternate with euthymic periods. It causes serious disability with poor outcome, increased suicidality risk, and significant societal costs. This chapter describes the findings of the PET/SPECT research efforts and the current ideas on the pathophysiology of bipolar
Haarman, Bartholomeus C. M. +5 more
openaire +2 more sources
Pediatric Bipolar Disorder [PDF]
In the past decade, interest in and research on pediatric bipolar disorder (BD) has increased substantially. Prevalence rates of the disorder have doubled in outpatient settings, while twice as many research articles on pediatric BD were published in the past five years as in the prior decade.
Ellen, Leibenluft, Brendan A, Rich
openaire +2 more sources
Melt Grafting of Geometry‐Tailored Voltage Stabilizers for High‐Performance Polypropylene Insulation
A scalable one‐step melt grafting strategy is developed to enhance the dielectric properties of isotactic polypropylene by covalently incorporating thermally stable aromatic voltage stabilizers. This solvent‐free approach improves volume resistivity and DC breakdown strength through deep trap formation and charge localization, offering a sustainable ...
Nazirul Mubin bin Normansah +9 more
wiley +1 more source
Characterizing heterogeneity in motivational impairments in psychosis
IntroductionMotivational impairments are a hallmark symptom of psychotic disorders. However, motivation is a multidimensional construct believed to be underpinned by different neural mechanisms and differentially impaired both between and within ...
Kathryn E. Lewandowski +5 more
doaj +1 more source
A Longitudinal Pilot Proton MRS Investigation of the Manic and Euthymic States of Bipolar Disorder [PDF]
Several lines of evidence implicate dysfunction in brain energy production as a key component of bipolar disorder. In particular, elevated brain lactate levels observed in this condition suggest a shift from aerobic to anaerobic metabolism, possibly as a
Brady, Roscoe Owen +7 more
core +1 more source
Objectives Over the past two decades, there has been tremendous growth in research regarding bipolar disorder (BD) among children and adolescents (ie, pediatric BD [PBD]).
B. Goldstein +17 more
semanticscholar +1 more source
An epi‐intraneural interface is developed through in silico optimization and a novel tridimensional microfabrication pipeline. The device integrates penetrating and epineural contacts on a flexible substrate. Mechanical, electrochemical, and in vivo testing in rat and pig reveal robust implantation, low‐threshold activation, and site‐dependent ...
Federico Ciotti +14 more
wiley +1 more source
In vivo evaluation of cortical thickness with magnetic resonance imaging in patients with bipolar disorder [PDF]
Changes in cortical thickness can be related to neuropsychiatric disorders and neurodegenerative processes. Previous studies have been conducted to characterize the pattern of changes in cortical thickness in several psychiatric diseases.
DOMINGUES, Romeu Cortes +6 more
core +1 more source
Tin hexathiophosphate memristors leverage intrinsic nanopores together with a guided filament formation strategy to regulate titanium ion motion and switching behavior. The devices support reliable nonvolatile memory and reconfigurable logic‐in‐memory, demonstrating 14 Boolean logic functions in a single cell.
Thaw Tint Te Tun +7 more
wiley +1 more source
The clinical trajectory of emerging bipolar disorder among the high-risk offspring of bipolar parents: current understanding and future considerations. [PDF]
Relatively little is known about the onset of bipolar disorder, yet the early illness course is already associated with significant morbidity and mortality.
Duffy, A. +3 more
core +3 more sources

