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Bipolar Disorder [PDF]

open access: yesDepression Research and Treatment, 2012
Bipolar disorder is a serious disorder of mood that is associated with considerable psychosocial and economic morbidity. Even though it is more common than previously thought, it has until relatively recently been somewhat neglected in terms of research when compared to disorders such as schizophrenia and major depression. Recent advances in the fields
COLOMBO , CRISTINA ANNA   +2 more
  +10 more sources

Bipolar disorder [PDF]

open access: yesEvidence-Based Mental Health, 2003
Bipolar disorder, with mood swings between depression and mania, may affect up to 1.5% of adults, and increases the risk of suicide and disability. Most people improve over time, but two thirds may have residual dysfunction, and at least 40% may have recurrent episodes.We conducted a systematic review and aimed to answer the following clinical ...
Geddes, J, Briess, D
openaire   +9 more sources

Bipolar disorders

open access: yesNature Reviews Disease Primers, 2018
Bipolar disorders are chronic and recurrent disorders that affect >1% of the global population. Bipolar disorders are leading causes of disability in young people as they can lead to cognitive and functional impairment and increased mortality, particularly from suicide and cardiovascular disease. Psychiatric and nonpsychiatric medical comorbidities are
Vieta, Eduard   +8 more
  +9 more sources

Staging Bipolar Disorder [PDF]

open access: yesNeurotoxicity Research, 2010
The purpose of this study was to analyze the evidence supporting a staging model for bipolar disorder. The authors conducted an extensive Medline and Pubmed search of the published literature using a variety of search terms (staging, bipolar disorder, early intervention) to find relevant articles, which were reviewed in detail.
Vieta i Pascual, Eduard, 1963-   +2 more
openaire   +4 more sources

Assessing neural tuning for object perception in schizophrenia and bipolar disorder with multivariate pattern analysis of fMRI data. [PDF]

open access: yes, 2017
IntroductionDeficits in visual perception are well-established in schizophrenia and are linked to abnormal activity in the lateral occipital complex (LOC). Related deficits may exist in bipolar disorder. LOC contains neurons tuned to object features.
Altshuler, Lori L   +8 more
core   +3 more sources

Bipolar disorder

open access: yesDialogues in Clinical Neuroscience, 1999
Bipolar disorder's unique combination of three characteristics - clear genetic diathesis, distinctive clinical features, early availability of an effective treatment (lithium) - explains its special place in the history of psychiatry and its contribution to the current explosive growth of neuroscience.
F K, Goodwin, S N, Ghaemi
openaire   +3 more sources

Lamotrigine in the treatment of schizoaffective disorder [PDF]

open access: yes, 1998
There is accumulating evidence for the efficacy of lamotrigine in the treatment of bipolar disorder, including bipolar depression, both as monotherapy and in combination with sodium valproate.
Erfurth, Andreas   +2 more
core   +1 more source

Differential efficacy of lithium and carbamazepine in the prophylaxis of bipolar disorder: Results of the MAP study [PDF]

open access: yes, 2000
In a randomized clinical trial with an observation period of 2.5 years, the differential efficacy of lithium versus carbamazepine was compared in 171 bipolar patients (DSM-IV).
Greil, Waldemar, Kleindienst, Nikolaus
core   +1 more source

Bipolar disorder

open access: yesMedicine, 2011
Bipolar disorder is rapidly becoming the primary diagnosis in adult psychiatry. It represents a wide spectrum of disorder all sharing common features of elated and depressed mood. The early descriptions of symptom-free euthymia have long been dismissed and the chronic and enduring deficits associated with the disorder are beginning to be better ...
openaire   +4 more sources

Cognitive function and lifetime features of depression and bipolar disorder in a large population sample: Cross-sectional study of 143,828 UK Biobank participants [PDF]

open access: yes, 1996
Background: This study investigated differences in cognitive performance between middle-aged adults with and without a lifetime history of mood disorder features, adjusting for a range of potential confounders.
Cullen, B.   +10 more
core   +2 more sources

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