Results 11 to 20 of about 3,170,462 (239)

Genome-wide association study of over 40,000 bipolar disorder cases provides new insights into the underlying biology

Nature Genetics, 2021
Bipolar disorder is a heritable mental illness with complex etiology. We performed a genome-wide association study of 41,917 bipolar disorder cases and 371,549 controls of European ancestry, which identified 64 associated genomic loci.
N. Mullins, A. Forstner, K. O’Connell, B. Coombes, J. Coleman, Zhen Qiao, T. Als, T. Bigdeli, S. Børte, J. Bryois, A. Charney, O. K. Drange, M. Gandal, S. Hagenaars, M. Ikeda, Nolan Kamitaki, Minsoo Kim, Kristi Krebs, Georgia Panagiotaropoulou, B. Schilder, Laura G. Sloofman, S. Steinberg, V. Trubetskoy, B. Winsvold, H. Won, L. Abramova, K. Adorjan, E. Agerbo, M. A. Al Eissa, D. Albani, N. Alliey-Rodriguez, A. Anjorin, V. Antilla, A. Antoniou, S. Awasthi, J. Baek, Marie Bækvad-Hansen, N. Bass, M. Bauer, Eva C. Beins, Sarah E. Bergen, A. Birner, C. Bøcker Pedersen, E. Bøen, M. Boks, R. Bosch, M. Brum, B. Brumpton, N. Brunkhorst-Kanaan, M. Budde, J. Bybjerg-Grauholm, W. Byerley, M. Cairns, M. Casas, P. Cervantes, Toni‐Kim Clarke, C. Cruceanu, A. Cuellar-Barboza, J. Cunningham, D. Curtis, P. Czerski, A. Dale, N. Dalkner, F. David, F. Degenhardt, S. Djurovic, Amanda Dobbyn, A. Douzenis, T. Elvsåshagen, V. Escott-Price, I. Ferrier, A. Fiorentino, T. Foroud, L. Forty, J. Frank, O. Frei, N. Freimer, L. Frisén, K. Gade, J. Garnham, J. Gelernter, Marianne Giørtz Pedersen, I. Gizer, S. Gordon, K. Gordon-Smith, T. Greenwood, J. Grove, J. Guzmán-Parra, Kyooseob Ha, M. Haraldsson, M. Hautzinger, U. Heilbronner, D. Hellgren, S. Herms, P. Hoffmann, P. Holmans, L. Huckins, S. Jamain, Jessica S. Johnson, J. Kalman, Y. Kamatani, J. Kennedy, S. Kittel-Schneider, J. Knowles, M. Kogevinas, M. Koromina, T. Kranz, H. Kranzler, M. Kubo, R. Kupka, S. Kushner, C. Lavebratt, J. Lawrence, M. Leber, Heon-Jeong Lee, Phil H. Lee, S. Levy, Catrin E Lewis, C. Liao, S. Lucae, M. Lundberg, D. Macintyre, S. Magnusson, W. Maier, A. Maihofer, D. Malaspina, E. Maratou, Lina Martinsson, M. Mattheisen, S. Mccarroll, N. McGregor, P. McGuffin, J. Mckay, H. Medeiros, S. Medland, V. Millischer, G. Montgomery, J. Moran, D. Morris, Thomas W. Mühleisen, N. O’Brien, C. O’Donovan, Loes M. Olde Loohuis, L. Oruč, S. Papiol, A. Pardiñas, A. Perry, A. Pfennig, E. Porichi, J. Potash, D. Quested, T. Raj, M. Rapaport, J. R. DePaulo, E. Regeer, J. Rice, F. Rivas, M. Rivera, Julian Roth, P. Roussos, D. Ruderfer, C. Sánchez-Mora, E. Schulte, F. Senner, S. Sharp, P. Shilling, E. Sigurdsson, L. Sirignano, C. Slaney, O. Smeland, Danny J. Smith, J. Sobell, Christine Søholm Hansen, M. Soler Artigas, A. Spijker, Dan J Stein, J. Strauss, B. Świątkowska, C. Terao, T. Thorgeirsson, Claudio Toma, P. Tooney, Evangelia Eirini Tsermpini, M. Vawter, H. Vedder, J. Walters, S. Witt, S. Xi, Wei Xu, J. Yang, A. Young, Hannah Young, P. Zandi, Hang Zhou, L. Zillich, R. Adolfsson, I. Agartz, M. Alda, L. Alfredsson, Gulja Babadjanova, L. Backlund, B. Baune, F. Bellivier, S. Bengesser, W. Berrettini, D. Blackwood, M. Boehnke, A. Børglum, G. Breen, V. Carr, S. Catts, A. Corvin, N. Craddock, U. Dannlowski, D. Dikeos, T. Esko, B. Étain, P. Ferentinos, M. Frye, J. Fullerton, M. Gawlik, E. Gershon, F. Goes, Melissa J. Green, M. Grigoroiu-Serbanescu, J. Hauser, F. Henskens, J. Hillert, K. Hong, D. Hougaard, C. Hultman, K. Hveem, N. Iwata, A. Jablensky, I. Jones, L. Jones, R. Kahn, J. Kelsoe, G. Kirov, M. Landén, M. Leboyer, C. Lewis, Qingqin S. Li, J. Lissowska, C. Lochner, C. Loughland, N. Martin, C. Mathews, F. Mayoral, S. McElroy, A. McIntosh, F. McMahon, I. Melle, P. Michie, L. Milani, P. Mitchell, G. Morken, O. Mors, P. Mortensen, B. Mowry, B. Müller-Myhsok, R. Myers, B. Neale, C. Nievergelt, M. Nordentoft, M. Nöthen, M. O’Donovan, K. Oedegaard, T. Olsson, M. Owen, S. Paciga, C. Pantelis, C. Pato, M. Pato, G. Patrinos, R. Perlis, D. Posthuma, J. Ramos-Quiroga, A. Reif, E. Reininghaus, M. Ribasés, M. Rietschel, S. Ripke, G. Rouleau, Takeo Saito, U. Schall, M. Schalling, P. Schofield, T. Schulze, L. Scott, R. Scott, A. Serretti, C. Shannon Weickert, J. Smoller, H. Stefánsson, K. Stefánsson, E. Stordal, F. Streit, P. Sullivan, G. Turecki, A. Vaaler, E. Vieta, J. Vincent, I. Waldman, T. Weickert, T. Werge, N. Wray, J. Zwart, J. Biernacka, J. Nurnberger, S. Cichon, H. Edenberg, E. Stahl, A. McQuillin, A. Di Florio, R. Ophoff, O. Andreassen   +316 more
semanticscholar   +1 more source

20-Year Trends in the Pharmacologic Treatment of Bipolar Disorder by Psychiatrists in Outpatient Care Settings.

American Journal of Psychiatry, 2020
OBJECTIVE Pharmacological options for treating bipolar disorder have increased over the past 20 years, with several second-generation antipsychotics receiving regulatory approval in the 1990s.
T. Rhee, M. Olfson, A. Nierenberg, S. Wilkinson   +3 more
semanticscholar   +1 more source

The 2020 Royal Australian and New Zealand College of psychiatrists clinical practice guidelines for mood disorders: Bipolar disorder summary

Bipolar Disorders, 2020
To provide a succinct, clinically useful summary of the management of bipolar disorder, based on the 2020 Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for mood disorders (MDcpg2020).
G. Malhi, E. Bell, P. Boyce, Darryl L Bassett, M. Berk, R. Bryant, M. Gitlin, Amber Hamilton, P. Hazell, M. Hopwood, B. Lyndon, R. McIntyre, Grace Morris, R. Mulder, R. Porter, Ajeet B. Singh, L. Yatham, A. Young, G. Murray   +18 more
semanticscholar   +1 more source

Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 guidelines for the management of patients with bipolar disorder

Bipolar Disorders, 2018
The Canadian Network for Mood and Anxiety Treatments (CANMAT) previously published treatment guidelines for bipolar disorder in 2005, along with international commentaries and subsequent updates in 2007, 2009, and 2013.
L. Yatham, S. Kennedy, S. Parikh, A. Schaffer, D. Bond, B. Frey, Verinder Sharma, B. Goldstein, S. Rej, S. Beaulieu, M. Alda, G. MacQueen, R. Milev, A. Ravindran, C. O’Donovan, D. Mcintosh, R. Lam, G. Vázquez, F. Kapczinski, R. McIntyre, J. Kozicky, S. Kanba, B. Lafer, T. Suppes, J. Calabrese, E. Vieta, G. Malhi, R. Post, M. Berk   +28 more
semanticscholar   +1 more source

Violent suicide attempt history in elderly patients with bipolar disorder: The role of sex, abdominal obesity, and verbal memory: Results from the FACE-BD cohort (FondaMental Advanced center of Expertise for Bipolar Disorders) [PDF]

Journal of Affective Disorders, Elsevier, 2022, 296, pp.265-276, 2022
Background: Bipolar disorder (BD) is a chronic, lifelong condition, associated with increased risk of obesity, cognitive impairment, and suicidal behaviors. Abdominal obesity and a higher risk of violent suicide attempt (SA) seem to be shared correlates with older age, BD, and male sex until middle age when menopause-related female body changes occur ...
arxiv   +1 more source

Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder

Science, 2018
INTRODUCTION Our understanding of the pathophysiology of psychiatric disorders, including autism spectrum disorder (ASD), schizophrenia (SCZ), and bipolar disorder (BD), lags behind other fields of medicine.
M. Gandal, Pan Zhang, Evi Hadjimichael, R. Walker, Chao Chen, Shuang Liu, H. Won, H. van Bakel, M. Varghese, Yongjun Wang, Annie W Shieh, J. Haney, Sepideh Parhami, Judson Belmont, Minsoo Kim, Patricia Moran Losada, Z. Khan, J. Mleczko, Yan Xia, R. Dai, Daifeng Wang, Yucheng T. Yang, Min Xu, K. Fish, P. Hof, J. Warrell, Dominic Fitzgerald, K. White, A. Jaffe, M. Peters, M. Gerstein, Chunyu Liu, L. Iakoucheva, D. Pinto, D. Geschwind   +34 more
semanticscholar   +1 more source

Long-Short Ensemble Network for Bipolar Manic-Euthymic State Recognition Based on Wrist-worn Sensors [PDF]

IEEE Pervasive Computing (2022) 1-12, 2021
Manic episodes of bipolar disorder can lead to uncritical behaviour and delusional psychosis, often with destructive consequences for those affected and their surroundings. Early detection and intervention of a manic episode are crucial to prevent escalation, hospital admission and premature death.
arxiv   +1 more source

How to make online mood-monitoring in bipolar patients a success? A qualitative exploration of requirements

International Journal of Bipolar Disorders, 2021
Background The Life-Chart Method (LCM) is an effective self-management treatment option in bipolar disorder (BD). There is insufficient knowledge about the consumers’ needs and desires for an e-monitoring solution.
B. Geerling, S. M. Kelders, R. W. Kupka, A. W. M. M. Stevens, E. T. Bohlmeijer   +4 more
doaj   +1 more source

Elevated Familial Cardiovascular Burden Among Adolescents With Familial Bipolar Disorder

Frontiers in Psychiatry, 2019
Background: Bipolar disorder (BD) is one of the most heritable medical conditions, and certain phenotypic characteristics are especially familial in BD. BD is also strongly associated with elevated and premature cardiovascular disease (CVD) morbidity and
Simina Toma, Simina Toma, Lisa Fiksenbaum, Danielle Omrin, Benjamin I. Goldstein, Benjamin I. Goldstein, Benjamin I. Goldstein   +6 more
doaj   +1 more source

Lithium induced hypercalcemia: an expert opinion and management algorithm

International Journal of Bipolar Disorders, 2022
Background Lithium is the gold standard prophylactic treatment for bipolar disorder. Most clinical practice guidelines recommend regular calcium assessments as part of monitoring lithium treatment, but easy-to-implement specific management strategies in ...
Zoltan Kovacs, Peter Vestergaard, Rasmus W. Licht, Sune P. V. Straszek, Anne Sofie Hansen, Allan H. Young, Anne Duffy, Bruno Müller-Oerlinghausen, Florian Seemueller, Gabriele Sani, Janusz Rubakowski, Josef Priller, Lars Vedel Kessing, Leonardo Tondo, Martin Alda, Mirko Manchia, Paul Grof, Phillip Ritter, Tomas Hajek, Ute Lewitzka, Veerle Bergink, Michael Bauer, René Ernst Nielsen   +22 more
doaj   +1 more source