Results 31 to 40 of about 387,451 (287)

Impact of a cis-associated gene expression SNP on chromosome 20q11.22 on bipolar disorder susceptibility, hippocampal structure and cognitive performance. [PDF]

, 2016
BackgroundBipolar disorder is a highly heritable polygenic disorder. Recent enrichment analyses suggest that there may be true risk variants for bipolar disorder in the expression quantitative trait loci (eQTL) in the brain.AimsWe sought to assess the ...
Bellivier, F., Bergen, S. E., Castelao, E., Chen, C., Chen, C., Cichon, S., Degenhardt, F. A., Dong, Q., Etain, B., Fuller, C. K., Fullerton, J. M., Gordon, S. D., Grigoroiu-Serbanescu, M., Henry, C., Hultman, C. M., Hyde, T. M., Jamain, S., Kahn, J. P., Kleinman, J. E., Kutalik, Z., Landen, M., Leboyer, M., Li, H., Li, M., Li, X., Liu, C., Liu, J., Luo, X. J., Martin, N. G., Mattheisen, M., Medland, S. E., Mitchell, P. B., Montgomery, G. W., Moo, D. S. Consortium, Muhleisen, T. W., Nothen, M. M., Preisig, M., Rietschel, M., Schofield, P. R., Schulze, T. G., Su, B., Swedish Bipolar Study, Group, Weinberger, D. R., Wright, A., Yao, Y. G., Zhang, C., Zhang, W.   +46 more
core   +1 more source

How patients contribute to an online psychoeducation forum for bipolar disorder: a virtual participant observation study [PDF]

, 2015
Background: In a recent exploratory randomized controlled trial, an online psychoeducation intervention for bipolar disorder has been found to be feasible and acceptable to patients and may positively impact on their self-management behaviors and ...
Poole, Ria, Simpson, Sharon, Smith, Daniel   +2 more
core   +3 more sources

Bipolar disorder longitudinal study in Nigeria – Preliminary data on demographic and clinical findings of the study cohort

Journal of Affective Disorders Reports, 2023
Background: Bipolar disorder, severe mood disorder characterised by its ability to swing between two contrasting poles of low and elated mood with a return to relatively normal level of functioning, has a lifetime prevalence of up to 2.4%, a heterogenous
Frances Nkechi Adiukwu, Olufisayo Adesokun, Izuchukwu Metu, Isoboye Jack, Collins Ekwubiri, joy Iyanuoluwapo Igbari, Chidozie Chukwujekwu   +6 more
doaj   +1 more source

Correlation between Peripheral Levels of Brain-Derived Neurotrophic Factor and Hippocampal Volume in Children and Adolescents with Bipolar Disorder

Neural Plasticity, 2015
Pediatric bipolar disorder (PBD) is a serious mental disorder that affects the development and emotional growth of affected patients. The brain derived neurotrophic factor (BDNF) is recognized as one of the possible markers of the framework and its ...
Tatiana Lauxen Peruzzolo, Mauricio Anes, Andre de Moura Kohmann, Ana Claudia Mércio Loredo Souza, Ramiro Borges Rodrigues, Juliana Basso Brun, Roberta Peters, Bianca Wollenhaupt de Aguiar, Flavio Kapczinski, Silzá Tramontina, Luis Augusto Paim Rohde, Cristian Patrick Zeni   +11 more
doaj   +1 more source

Cognitive function in bipolar disorder

European Psychiatry, 2022
Introduction In bipolar disorder, cognitive deficits persist across mood episodes and euthymia. Despite recent advances, cognitive impairment in bipolar disorder remains poorly understood.
T. Sparding
doaj   +1 more source

Examining cognition across the bipolar / schizophrenia diagnostic spectrum [PDF]

, 2018
BACKGROUND: Cognitive impairments are well-established features of schizophrenia, but there is ongoing debate about the nature and degree of cognitive impairment in patients with schizoaffective disorder and bipolar disorder.
Hamshere, Marian L., Hubbard, Leon, Jones, Ian, Legge, Sophie, Lynham, Amy, Owen, Michael, Tansey, Katherine, Walters, James   +7 more
core   +1 more source

Poor self-reported sleep is associated with prolonged white matter T2 relaxation in psychotic disorders

Frontiers in Psychiatry
BackgroundPsychotic disorders are characterized by white matter (WM) abnormalities; however, their relationship with the various aspects of illness presentation remains unclear.
Umit Haluk Yesilkaya, Umit Haluk Yesilkaya, Xi Chen, Xi Chen, Lauren Watford, Emma McCoy, Meltem Sen, Ilgin Genc, Fei Du, Fei Du, Dost Ongur, Dost Ongur, Cagri Yuksel, Cagri Yuksel   +13 more
doaj   +1 more source

Associations between brain‐derived neurotrophic factor and cognitive impairment in panic disorder

Brain and Behavior, 2020
Introduction Our study was designed to examine the relationship between Brain‐Derived Neurotrophic Factor (BDNF) genotypes (rs6265, Val66Met), BDNF plasma levels, and cognitive impairment in Chinese patients with panic disorder (PD).
Wenchen Wang, Yuanyuan Liu, Shuqing Luo, Xiaoyun Guo, Xingguang Luo, Yong Zhang   +5 more
doaj   +1 more source

El tratamiento a largo plazo del trastorno bipolar

Psicodebate, 2015
Las indicaciones medicamentosas para el tratamiento del trastorno bipolar (TB) requieren de una ponderación de la necesidad de tratamiento del episodio en curso y su evolución a largo plazo. Los objetivos principales radicarán en estabilizar el ánimo,
Leonardo Tondo
doaj   +1 more source

Is Bipolar Disorder the Consequence of a Genetic Weakness or Not Having Correctly Used a Potential Adaptive Condition?

Brain Sciences, 2022
It is hypothesized that factors associated with bipolar disorder could, uer defined conditions, produce adaptive behaviors. The aim is to verify whether a genetic feature associated with bipolar disorder can be found in people without bipolar disorder ...
Mauro Giovanni Carta, Goce Kalcev, Alessandra Scano, Diego Primavera, Germano Orrù, Oye Gureye, Giulia Cossu, Antonio Egidio Nardi   +7 more
doaj   +1 more source