Results 41 to 50 of about 5,533,129 (112)

MSC‐Derived Exosomal lnc‐AGT‐3: A Novel Anti‐Angiogenic Target in Age‐Related Macular Degeneration Through p53 Signaling Pathway

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
MSC‐derived exosomes deliver lnc‐AGT‐3 to vascular endothelial cells, where it binds hnRNP K in the nucleus. This interaction inhibits p53 ubiquitination, enhancing p53 stabilization and transcriptional activation of anti‐angiogenic targets TSP1. Consequently, p53‐mediated signaling is potentiated, effectively suppressing choroidal neovascularization ...
Lingjie Kong   +9 more
wiley   +1 more source

Single‐Cell RNA Sequencing of Retina Reveals Nna1 Upregulation in Myopic Diabetic Retinopathy as a Protective Factor Against Diabetic Damage

open access: yesAdvanced Science, Volume 13, Issue 5, 27 January 2026.
This study investigates a schematic overview of the mechanistic pathways. The relationship between myopia and DR has long been of clinical interest. In diabetic mice, Nna1 expression is downregulated, whereas in diabetic mice with FDM, Nna1 expression is upregulated–particularly in Müller cells–accompanied by decreased vascular endothelial growth ...
Lihui Xie   +5 more
wiley   +1 more source

Welfare Gains and Losses in Sunspot Equilibria [PDF]

open access: yes
We study a standard two period exchange economy with one nominal asset. As is well known there is a continuum of sunspot equilibria around each efficient equilibrium.
Atsushi Kajii
core  

Investigating the Role of Zebrafish Retinoschisin Homologs Rs1a and Rs1b During Retinal Development

open access: yesDevelopmental Neurobiology, Volume 86, Issue 1, January 2026.
ABSTRACT Deficiency in the retinoschisin protein (RS1) causes X‐linked juvenile retinoschisis (XLRS), a retinal degenerative disease that disrupts retinal layers and forms cystic cavities. In addition to its structural function, RS1 is believed to play a role in retinal development.
Isa van der Veen   +4 more
wiley   +1 more source

P-193 - Employment outcomes in people with bipolar disorder : a systematic review [PDF]

open access: yes, 2012
Objectives We conducted a systematic review in order to identify the long term employment outcomes of people with Bipolar Disorder. Our aims were to identify the proportions working over time, the nature of employment status change over time and whether
Marwaha, Steven   +8 more
core   +1 more source

Expanding the Genotypic Landscape of Congenital Stationary Night Blindness in an Ethnically Diverse Canadian Population

open access: yesHuman Mutation, Volume 2026, Issue 1, 2026.
Congenital stationary night blindness (CSNB) is a rare and typically nonprogressive group of genetically heterogeneous disorders resulting in impaired night vision and high myopia with varying levels of visual impairment. Despite being a rare disease with a prevalence of 1:294,000, variants in 22 genes have been associated with specific CSNB phenotypes.
Jennifer Ling   +5 more
wiley   +1 more source

Solar Storm Type Classification Using Probabilistic Neural Network compared with the Self-Organizing Map [PDF]

open access: yes, 2012
One of the task of the LAPAN is making observation and forecasting of solar storms disturbance. This disturbances can affect the earths electromagnetic field that disrupt the electronic and navigational equipment on earth.
Setiahadi, Bambang   +3 more
core  

Associations Between Baseline Biomarkers and Functional Outcomes in Patients With Diabetic Macular Edema After Anti‐VEGF Treatment

open access: yesJournal of Ophthalmology, Volume 2026, Issue 1, 2026.
Objective To investigate associations between baseline structural and functional biomarkers and 6‐month post‐treatment best‐corrected visual acuity (BCVA) among patients with diabetic macular edema (DME) receiving intravitreal anti‐VEGF therapy. Methods Data from patients treated at Hebei Eye Hospital between December 2022 and January 2024 were ...
Yi Cai   +8 more
wiley   +1 more source

A pilot study of positive mood induction in euthymic bipolar subjects compared with healthy controls [PDF]

open access: yes, 2006
Background. Demonstrating differences between euthymic bipolar subjects and healthy controls in response to positive (happy) mood induction may help elucidate how mania evolves.
Lam, D   +9 more
core   +1 more source

Schizophrenia and Bipolar Disorder in Urban Areas [PDF]

open access: yes, 2007
Background Earlier studies have shown that schizophrenic patients are more likely to be living in densely populated inner city areas, whereas bipolar patients are more widely distributed.
Cooke, Angela   +5 more
core   +2 more sources

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