Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Association of Mothers' Perception of Neighborhood Quality and Maternal Resilience with Risk of Preterm Birth. [PDF]
We examined the associations of mothers' perception of neighborhood quality and maternal resilience with risk of preterm birth and whether maternal resilience moderated the effect of neighborhood quality perception.
Bhatia, Namrata +4 more
core +2 more sources
Pregnancy outcomes among daycare employees in Finland
OBJECTIVE: The aim of this study was to investigate whether working as a daycare employee increases the risk of perinatal death, pre-term birth, low birth weight, smallness for gestational age, or congenital malformations.
Anita Riipinen +4 more
doaj +1 more source
Life, Birth and Death in Democritus. Atomistic Reflections Between Physics and Ethics
The subject of life, birth and death constitutes one of the main topics in Democritus’ reflection on human questions. He seeks to understand what men think about the processes of birth and death and how they, accordingly, determine their behavior and ...
Miriam Campolina Diniz Peixoto
doaj +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Survival and coexistence for a multitype contact process
We study the ergodic theory of a multitype contact process with equal death rates and unequal birth rates on the $d$-dimensional integer lattice and regular trees.
Cox, J. Theodore, Schinazi, Rinaldo B.
core +1 more source
The effects of socioeconomic status and indices of physical environment on reduced birth weight and preterm births in Eastern Massachusetts [PDF]
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work
A Ellaway +50 more
core +3 more sources
Gebelerin Gebelikte İyi Olma Hali ve Gebelik Deneyimlerinin Doğum İnançlarıyla İlişkisi
Giriş: Prenatal dönemde, olumlu deneyimler, gebelikte iyi olma hali, sağlıklı bir doğum süreci için önemlidir. Amaç: Araştırmada gebelerin gebelikte iyi olma hali ve gebelik deneyimlerinin doğum inançlarıyla ilişkisini incelemek amaçlandı.
Zehra Çerçer, Duygu Ayar
doaj +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Ambient Air Toxic Releases and Adverse Pregnancy Outcomes in Allegheny County, Pennsylvania [PDF]
Previous studies have shown that women exposed to certain air pollutants are at an increased risk for preterm delivery and/or delivering a low birth weight newborn. Preterm delivery and low birth weight are associated with an increased risk for morbidity
Carman, April E
core

