Results 201 to 210 of about 2,893,142 (314)

Cohort Profile: The FinnBrain Birth Cohort Study (FinnBrain) [PDF]

International Journal of Epidemiology, 2017
Linnea, Karlsson, Mimmi, Tolvanen, Noora M, Scheinin, Henna-Maria, Uusitupa, Riikka, Korja, Eeva, Ekholm, Jetro J, Tuulari, Marjukka, Pajulo, Minna, Huotilainen, Tiina, Paunio, Hasse, Karlsson   +10 more
openaire   +2 more sources

Autophagy Orchestrates Anti‐Tumor Immunity to Enhance Chemosensitivity via the FBXW2/C/EBPβ/TIMP‐2 Axis in Colorectal Cancer

Advanced Science, EarlyView.
Chemotherapy leverages tumor‐cell autophagy to reshape the colorectal cancer immune microenvironment. Autophagy degrades FBXW2 to promote C/EBPβ‐mediated TIMP‐2 transcription and MMP‐9 suppression, driving intra‐tumoral CD8+ T‐cell infiltration. Targeting MMP‐2/9 or restoring TIMP‐2 overcomes chemo‐resistance in autophagy‐deficient tumors. ABSTRACT The
Bing Cheng, Chaoying Wei, Zhitong Niu, Jinxin Chen, Guojie Long, Yingzhen Weng, Qiufeng Liu, Yue Jiang, Panpan Wang, Ronghua Zhang, Qiang Yu, Xiaojian Wu, Wenyu Wang   +12 more
wiley   +1 more source

Cohort profile: Sheyang Mini Birth Cohort Study (SMBCS). [PDF]

BMJ Open
Zhang J, Guo Q, Qi X, Zheng M, Liu P, Guo J, Dai Y, Wang Z, Zhang B, Yang J, Wu C, Zhou Z.   +11 more
europepmc   +1 more source

Targeting the PHB2–ACSL3 Lipid‐Remodeling Axis Overcomes Cisplatin Resistance by Restoring Ferroptosis in Gastric Cancer

Advanced Science, EarlyView.
ABSTRACT Platinum‐based chemotherapy resistance remains a major obstacle in gastric cancer (GC) treatment. Through integrated transcriptomic profiling of cisplatin‐resistant xenografts and pharmacogenomic interrogation of the NCI‐60 dataset, we identified Prohibitin‐2 (PHB2) as a previously unrecognized determinant of chemoresistance.
Liang Xu, Wanying Xiang, Xinyue Wang, Yue Pan, Jing Gao, Jiezhen Yang, Yufei Wang, Zhipu Zhu, Man Tong, Lei Jin, Yan Ye   +10 more
wiley   +1 more source

Comparative social costs of six early years disadvantages: a birth cohort microsimulation study. [PDF]

J Epidemiol Community Health
Venkatesh S, Skarda I, Villadsen A, Warburton M, Mansukoski L, Mon-Williams M, Cookson R.   +6 more
europepmc   +1 more source

HTA of birth cohort testing for hepatitis C: a short report update

In 2017, an Irish National Clinical Guideline for Hepatitis Screening was endorsed by the Minister for Health which conditionally recommended offering once-off testing for hepatitis C to people born between 1965 and 1985 (that is, birth cohort testing ...
Health Information and Quality Authority (HIQA)
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AI‐Assisted Tumor Boundary Delineation via Targeted Ultrasmall Iron Oxide Nanoprobe for High‐Contrast HER2‐Positive Tumor Imaging

Advanced Science, EarlyView.
A novel targeted and pH‐responsive MRI contrast agent was integrated with a 3D nnU‐Net deep learning framework to enable accurate delineation of tumor boundary morphology in HER2‐positive breast cancer imaging. ABSTRACT Breast cancer continues to be a leading cause of cancer‐related mortality in women globally, where precise diagnosis and clear tumor ...
Jiaying Zheng, Yi Zhu, Xinrui Li, Sunxian Dai, Xiangyuan Ma, Hongwei Lu, Zhongling Wang, Benqing Zhou   +7 more
wiley   +1 more source

Impact of prenatal pyrethroid pesticide exposure on neonatal lymphocyte subsets and apoptosis: a birth cohort study. [PDF]

J Glob Health
Qi Z, Zhang L, Xiao X, Wu K, Chen S, Song X, Li Y.   +6 more
europepmc   +1 more source

CHST1 Drives Immunotherapy Resistance in Triple‐Negative Breast Cancer by Orchestrating an Immunosuppressive Microenvironment via the NKRF–CCL20–Macrophage Axis

Advanced Science, EarlyView.
Proposed model of CHST1‐associated immune remodeling in triple‐negative breast cancer. In CHST1‐low tumors, greater nuclear accumulation of NKRF is associated with repression of an NF‐κB‐related CCL20 transcriptional program and an immune‐inflamed microenvironment.
Shu‐Hao Jiang, Xiao‐Han Ying, Ruo‐Qing Wang, Qun Zhang, Li Chen, Zhi‐Ming Shao, Jun‐Jie Li   +6 more
wiley   +1 more source

Navajo Nation Birth Cohort Study logo

The study logo was created by Navajo Birth Cohort Study Team Member, Sandy Ramone, and has strong cultural significance. Iin\uc3\ua1 Nizh\uc3\ub3n\uc3\uad is translated to A Beautiful Life for Mother and Baby in English.

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