Results 211 to 220 of about 2,713,395 (314)

LRG1 Drives Pathological Angiogenesis by Disrupting Neutrophil Mitochondrial Homeostasis in Bladder Cancer

Advanced Science, EarlyView.
In bladder cancer, LRG1 binds to ANXA2 to trigger mitochondrial ROS‐dependent NETosis. This pathogenic cascade actively uncouples endothelial‐mural cell interactions, driving profound vascular destabilization. Consequently, targeting the LRG1‐ANXA2 axis attenuates the neutrophil burden and induces structural vascular normalization, offering a powerful ...
Dongshan Chen, Cong Zhang, Song Xue, Yuan Zeng, Haochen Cui, Chenfei Wang, Jiayi Feng, Lei Yan, Yuanwei Zang   +8 more
wiley   +1 more source

Maternal Conditions and Cesarean Delivery in a High-Burden Southeast Louisiana Birth Cohort: Associations and Limitations of Administrative Delivery Data. [PDF]

Healthcare (Basel)
Lang E, Smith D, Adorno M, Giarratano G, Ramos MD.   +4 more
europepmc   +1 more source

CA9‐Targeted PET Imaging for Noninvasive Discrimination of Clear Cell Renal Cell Carcinoma and Associated Tumor Biological Features

Advanced Science, EarlyView.
CA9‐targeted PET imaging could be a noninvasive approach to characterize clear cell renal cell carcinoma and associated tumor biology. PET uptake correlates with tumor CA9 expression and is linked to angiogenic activity, immune remodeling, and metabolic reprogramming.
Kailei Chen, Sixuan Cheng, Jian Shi, Ruijie Liu, Yilong Wu, Xin Zheng, Xinlun Song, Yunxuan Zhang, Lei Liu, Zhihao Wei, Qi Wang, Xinwei Li, Zirui Dong, Yuenan Liu, Hongmei Yang, Xiaoli Lan, Chunxia Qin, Dawei Jiang, Keshan Wang, Xiaoping Zhang   +19 more
wiley   +1 more source

Residential early-life air pollution exposure and oculomotor markers of cognitive workload in children: a prospective birth cohort study. [PDF]

EBioMedicine
Vanbrabant K, Renaers E, Engelen L, Reimann B, Croons H, Van Pee T, Vangeneugden M, Giesberts N, Ameloot M, Nawrot TS, Plusquin M.   +10 more
europepmc   +1 more source

HTA of birth cohort testing for hepatitis C: a short report update

In 2017, an Irish National Clinical Guideline for Hepatitis Screening was endorsed by the Minister for Health which conditionally recommended offering once-off testing for hepatitis C to people born between 1965 and 1985 (that is, birth cohort testing ...
Health Information and Quality Authority (HIQA)
core  

A Programmable Calcification Nanoplatform for Loco‐Regional Calcification‐Immune Hepatocellular Carcinoma Therapy

Advanced Science, EarlyView.
An in situ‐grown BP‐CaO2 nanoplatform supplies coordinated Ca2+, endogenous phosphate, and oxidative stress to convert tumor calcification from a passive endpoint into an active immune‐remodeling process. Widespread hydroxyapatite deposition is visualized by CT, while multi‐omics reveals MCOLN2 as a calcium‐responsive mediator linking biomineralization
Long Liu, Peng Li, Zhixiang Lu, Shuqin Xu, Juanjuan Wang, Kai Ma, Haodong Yu, Can Zhou, Hu Chen, Gang Liu, Yi Lyu, Shuang Bai   +11 more
wiley   +1 more source

Conduct problems and callous-unemotional traits in pre-schoolers: Psychosocial profiles in a Brazilian birth cohort. [PDF]

J Child Psychol Psychiatry
Perrone LR, Bauer A, Waller R, Domingues M, Curi Hallal P, Murray J.   +5 more
europepmc   +1 more source

Asian birth cohort studies

Allergology International
openaire   +3 more sources

Rewiring Pyroptosis to Potentiate Cancer Immunotherapy via a Gasdermin D Agonist Bypassing Caspase‐3

Advanced Science, EarlyView.
This work introduces a small‐molecule agonist, DIBDO, that bypasses Casp‐3 to directly trigger GSDMD‐mediated pyroptosis in tumors. Activated by glutathione, DIBDO generates singlet oxygen and molecular iodine, blocking Casp‐3 pathways and inducing immunogenic cell death.
Dan Zhao, Lingling Zhang, Yue Wen, Lianghui Cheng, Sidan Tian, Fanling Meng, Liang Luo   +6 more
wiley   +1 more source

An evaluation of antenatal corticosteroid use and timing in a large US birth cohort 2017-2021. [PDF]

Pregnancy (Hoboken)
Souter V, Combs CA, Painter I, Sitcov K, Foglia L, Edwards SM, Khalil A, Hoehn A.   +7 more
europepmc   +1 more source