Results 261 to 270 of about 2,893,142 (314)

Self‐Assembling Peptide‐Adjuvant Conjugate (SaPAC) Platform for Precision Cancer Immunotherapy

Advanced Science, EarlyView.
A self‐assembling peptide–adjuvant conjugate links neoantigens to TLR7 agonism, forming cationic nanoparticles that enhance lymph‐node retention, dendritic‐cell activation, and antitumor T‐cell immunity. This chemically defined platform shows how synchronized antigen and innate stimulation can be adapted across melanoma, bladder cancer, and triple ...
Yang‐Fan Wu, Jing‐Chu Hu, Ye‐Fan Hu, Wen‐Jun Li, Li Rong, Ren‐Hao Li, Yuan Yao, Lehan Hu, Xiao‐Lei Wang, Bao‐Zhong Zhang, Yicheng Lu, Shing‐Fung Chow, Canhui Su, Thomas Yau, Clive Yik‐Sham Chung, Jian‐Dong Huang   +15 more
wiley   +1 more source

Bowel Habits and Functional Constipation in Healthy Children-A Longitudinal Birth-Cohort Study. [PDF]

Acta Paediatr
Gatzinsky C, Sillén U, Bräutigam M, Kullberg-Lindh C, Thornberg S, Sjöström S.   +5 more
europepmc   +1 more source

Non‐Invasively Quantitative Raman Imaging for Calculation of Lymphatic Transport Kinetics of Micelles in Mice

Advanced Science, EarlyView.
Non‐invasively quantitative Raman imaging with stacking‐induced charge transfer‐enhanced Raman scattering (SICTERS) enables accurate measurement of concentrations and pharmacokinetic modeling of lymphatic transport of micelles in mice. This platform allows dynamic analysis of nanoparticle transport and underpins the design of effective lymph node ...
Yunlu Li, Hongzheng Lin, Sheng Yu, Yunhui Liao, Teng Huang, Zeyu Xiao, Wei Lu   +6 more
wiley   +1 more source

Multifunctional Nanovaccine‐Radiotherapy Synergy Drives Anti‐Tumor Immunity via Multi‐Cascade Cell Death for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
Machine‐learning‐driven transcriptomic analysis identifies FSTL3 as a key tumor‐microenvironment regulator in desmoplastic pancreatic adenocarcinoma. A cRGD‐modified liposome co‐loading gemcitabine and siFSTL3 serves as an irradiation‐triggered in situ nanovaccine. It synergizes with radiotherapy to induce ferroptosis and immunogenic cell death through
Chengyi Huang, Yushu Han, Xiang Liu, Chuanhao Wang, Xiaofei Zhu, Di Chen, Yangyang Gong, Liang Chen, Wenjuan Chen, Zhenyuan Miao, Bufu Tang, Huojun Zhang   +11 more
wiley   +1 more source

Associations Between Duration of Lactation and Maternal Risk of Obesity-Related Cancers-A Historical Birth Cohort Study. [PDF]

Matern Child Nutr
Christensen SH, Pedersen DC, Aarestrup J, Rasmussen KM, Baker JL, Bjerregaard LG.   +5 more
europepmc   +1 more source

Double burden of malnutrition by mid-childhood in an Indian birth cohort: a longitudinal study (2010-2021). [PDF]

Lancet Reg Health Southeast Asia
Yilmaz B, Mohan VR, John S, Kang G, Jebasingh F, Thomas N, Sonawane M, Kolthur-Seetharam U, Koshy B.   +8 more
europepmc   +1 more source

Generation Malawi: a family-based birth cohort investigating physical and mental health conditions in rural and urban Malawi - study protocol. [PDF]

BMJ Open
Nakanga WP, Stewart RC, Malava JK, Nindi P, Nzawa-Soko R, Nyanjagha I, Mainjeni A, Gondwe T, Umar E, Manda-Taylor L, Chorwe-Sungani G, Gladstone M, Kerac M, MacBeth A, Seward N, Patson N, Ngongondo M, Mathanga D, McIntosh AM, Crampin AC, Generation Malawi Collaborator Group.   +20 more
europepmc   +1 more source