Results 261 to 270 of about 2,713,395 (314)

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

Correction: Prenatal and birth factors associated with child autism diagnosis: a birth cohort perspective. [PDF]

Pediatr Res
Holland L, Drummond K, Thomson S, Sominsky L, Marx W, Love C, Dawson SL, Harrison LC, Saffery R, Symeonides C, Tang ML, Burgner D, Sly PD, Vuillermin P, Ponsonby AL, BIS Investigator group.   +15 more
europepmc   +1 more source

Toward Personalized Theranostics: A Modular PET Platform for Antibody‐Based Imaging and Therapy

Advanced Science, EarlyView.
This modular, site‐specific antibody platform enables customizable conjugates for PET imaging and therapy. Interchangeable payloads – including radiometals, cytotoxics, and fluorophores – support adaptable, multimodal applications with limited off‐target effects. In vivo, the DFO/DOTAGA bischelate immunoconjugate provided clear tumor delineation in PET/
Delphine Vivier, Megane Grah Kple, Julen Ariztia, Marion Leroux, Mathieu Moreau, Michael Claron, Maxime Cheveau, Adam Laouafa, Agnieszka Kownacka, Camille Petitot, John Simonet, Alexandre M. M. Dias, Sophie Poty, Charles Truillet, Bertrand Collin, Alexandra Oudot, Franck Denat   +16 more
wiley   +1 more source

Insights into neuroscience from the representative birth cohort samples of a multidisciplinary longitudinal study. [PDF]

Acta Neuropsychiatr
Harro J, Eensoo D, Kiive E, Villa I, Kurrikoff T, Mäestu J, Kanarik M, Laugus K, Sakala K, Veidebaum T.   +9 more
europepmc   +1 more source

AARS1‐Mediated RUNX3 K193 Lactylation Enhances the Activation and Cytotoxicity of CD8+T Cells in Smoking‐Related Emphysema

Advanced Science, EarlyView.
Exposure to CS causes an elevation of AARS1 levels, which increases the levels of RUNX3 lactylation at the K193 site and increases protein levels of RUNX3 through inhibition of autolysosomal degradation. Elevated RUNX3 levels promote CD8+T cell activation and augment their cytotoxicity, which induces alveolar epithelial cell death and facilitates the ...
Ying Zhu, Jiaheng Lin, Yifan Li, Qiaoqiao Zhou, Min Yu, Cheng Cheng, Kang Chang, Dang Lin, Tao Bian, Yan Wu, Lu Lu, Haibo Xia, Qizhan Liu   +12 more
wiley   +1 more source

Early childhood growth patterns and malnutrition in rural Southern India: a longitudinal study of a birth cohort. [PDF]

Front Public Health
Betha K, Dandge S, Kusneniwar G, Valsangkar S, Chaudhuri S, Agiwal V, A Y N, Pant H, Murthy GVS, Reddy PS.   +9 more
europepmc   +1 more source

A data driven approach to address missing data in the 1970 British birth cohort. [PDF]

BMC Med Res Methodol
Katsoulis M, Narayanan MK, Dodgeon B, Ploubidis GB, Silverwood RJ.   +4 more
europepmc   +1 more source

Feeding Type at 6-12 Months and Early-Life Iron-Related Hematologic Changes in Infants: A Longitudinal Birth Cohort Study. [PDF]

Nutrients
Jeong J, Jung M, Song J, Kim S, Ahn J, Kwon M, Kim MJ, Yang YJ, Kim J, Ahn K.   +9 more
europepmc   +1 more source

Misspecified seasonality adjustment in temperature and preterm birth studies may introduce severe bias: a real birth cohort-based simulation. [PDF]

Int J Epidemiol
Girgin S, Nevo D, Erez O, Raz R.
europepmc   +1 more source

Insights into US life expectancy stagnation from birth cohort mortality dynamics. [PDF]

Proc Natl Acad Sci U S A
Abrams L, Bramajo O, van Raalte A, Myrskylä M, Mehta NK.   +4 more
europepmc   +1 more source