Results 71 to 80 of about 2,893,142 (314)

Associations between maternal pre-pregnancy BMI and infant striatal mean diffusivity

BMC Medicine
Background It is well-established that parental obesity is a strong risk factor for offspring obesity. Further, a converging body of evidence now suggests that maternal weight profiles may affect the developing offspring’s brain in a manner that confers ...
Aylin Rosberg, Harri Merisaari, John D. Lewis, Niloofar Hashempour, Minna Lukkarinen, Jerod M. Rasmussen, Noora M. Scheinin, Linnea Karlsson, Hasse Karlsson, Jetro J. Tuulari   +9 more
doaj   +1 more source

Cohort Profile: 1970 British Birth Cohort (BCS70) [PDF]

International Journal of Epidemiology, 2006
The 1970 British Birth Cohort Study (BCS70) is an ongoing, multidisciplinary, longitudinal study. It takes as its subjects all those currently living in England, Scotland, and Wales who were born in a single week of 1970. To date there have been seven sweeps of the study, including the original birth survey.
Jane, Elliott, Peter, Shepherd
openaire   +2 more sources

Cognitive ability in childhood and cognitive decline in mid-life: longitudinal birth cohort study [PDF]

, 2004
Objective: To examine the association between cognitive ability in childhood and mid-life cognitive decline in the normal population. Design: Longitudinal, population based, birth cohort study. Participants: 2058 men and women born in 1946.
Richards, M, Fuhrer, R., Fuhrer, R, Shipley, B., Wadsworth, M.E.J., Shipley, B, Richards, M., Wadsworth, M E J   +7 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Intergenerational correlations in size at birth and the contribution of environmental factors: The Uppsala Birth Cohort Multigenerational Study, Sweden, 1915-2002.

, 2011
Sizes at birth of parents and their children are known to be correlated, reflecting in part the influence of fetal and maternal genes. Sociodemographic factors, regarded as aspects of the shared environment across generations, would also be expected to ...
De Stavola, Bianca L, I. Koupil, Leon, David A, De Stavola, B. L., Leon, D. A., Koupil, Ilona,, D. A. Leon, Koupil, Ilona, B. L. De Stavola   +8 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Health Technology Assessment of birth cohort Testing for Hepatitis C

, 2021
The Health Information and Quality Authority (HIQA) assessed whether birth cohort testing for hepatitis C should be introduced in Ireland.
Health Information and Quality Authority (HIQA)
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Aperiodic parameters of the fMRI power spectrum associate with preterm birth and neonatal age

Communications Biology
Perinatal period is a critical time for brain development and premature-born children have an elevated likelihood for neurodevelopmental conditions. While strong associations of structural magnetic resonance imaging with preterm birth and post-menstrual ...
Ilkka Suuronen, Silja Luotonen, Henry Railo, Antti Airola, Wajiha Bano, Harri Merisaari, Elmo P. Pulli, Isabella L. C. Mariani Wigley, Elena Vartiainen, Niloofar Hashempour, Hasse Karlsson, Linnea Karlsson, Morten L. Kringelbach, Dafnis Batalle, Jetro J. Tuulari   +14 more
doaj   +1 more source

Cohort Profile: The Lothian Birth Cohorts of 1921 and 1936 [PDF]

International Journal of Epidemiology, 2011
This cohort profile describes the origins, tracing, recruitment, testing and follow-up of the University of Edinburgh-based Lothian Birth Cohorts of 1921 (LBC1921; N = 550) and 1936 (LBC1936; N = 1091). The participants undertook a general intelligence test at age 11 years and were recruited for these cohorts at mean ages of 79 (LBC1921) and 70 ...
Deary, Ian J, Gow, Alan J, Pattie, Alison, Starr, John   +3 more
openaire   +2 more sources