Results 71 to 80 of about 799,321 (312)

Interactions between cortisol and lipids in human milk

open access: yesInternational Breastfeeding Journal, 2020
Background Human breast milk is one of the key early postnatal biological exposures for the developing child. It includes bioactive compounds, such as cortisol and fatty acids, which may be linked via the mother’s lipid metabolism.
Kaisa M. Linderborg   +6 more
doaj   +1 more source

The impact of income shocks on health: evidence from cohort data [PDF]

open access: yes, 2006
We study the effect of permanent income innovations on health for a prime-aged population. Using information on more than half a million individuals sampled over a twenty-five year period in three different cross-sectional surveys we aggregate data by ...
Adda, J., Banks, J., von Gaudecker, H.
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Early Life Socioeconomic Circumstance and Late Life Brain Hyperintensities : A Population Based Cohort Study [PDF]

open access: yes, 2014
Funding: Image acquisition and image analysis for this study was funded by the Alzheimer's Research Trust (now Alzheimer's Research UK). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the ...
A Forsdahl   +38 more
core   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Syphilis-attributable adverse pregnancy outcomes in China: a retrospective cohort analysis of 1187 pregnant women with different syphilis treatment

open access: yesBMC Infectious Diseases, 2019
Background Syphilis is responsible for a substantial burden of preventable adverse outcomes in pregnancy. The purpose of this study was to compare the frequency of adverse pregnancy outcomes among syphilis-seropositive women who received different ...
Huihui Liu   +11 more
doaj   +1 more source

Alexithymic Traits and Hair Cortisol Concentrations in Pregnant Women

open access: yesFrontiers in Psychiatry, 2020
IntroductionAlexithymia, a personality construct characterized by difficulties in identifying and expressing emotions, and an externally oriented thinking style, has been associated with a number of stress-related disorders, and physiological markers of ...
Jani Kajanoja   +16 more
doaj   +1 more source

Appropriate procedures to increase the adherence of children to blood collection: A cross‐sectional study

open access: yesHealth Science Reports, 2023
Background and Aim Venipuncture for blood collection elicits fear and pain in children. We investigated factors that affect satisfaction with health checkups that included blood collection in healthy 7–8‐year‐old children who underwent blood collection ...
Hideki Yui   +11 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Prevalence and Risk Factors of Incidental Findings in Brain MRIs of Healthy Neonates—The FinnBrain Birth Cohort Study

open access: yesFrontiers in Neurology, 2020
Background: Birth is a traumatic event with molding forces directed to the fetal skull, which may result in intracranial hemorrhages. However, the knowledge on prevalence and risk factors of incidental brain magnetic resonance imaging (MRI) findings in ...
Venla Kumpulainen   +23 more
doaj   +1 more source

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