Results 91 to 100 of about 2,893,142 (314)

Cohort Profile: The China-Anhui birth cohort study [PDF]

International Journal of Epidemiology, 2012
The China-Anhui Birth Cohort Study (C-ABCS) was set up to examine the delayed, cumulative and interactive effects of maternal environmental exposures on birth outcomes and children's development. The C-ABCS recruited pregnant women from six major cities of Anhui province, China, between November 2008 and October 2010.
Tao, Fang-biao, Hao, Jia-hu, Huang, Kun, Su, Pu-Yu, Cheng, Dai-juan, Xing, Xiu-ya, Huang, Zhao-hui, Zhang, Jing-li, Tong, Shilu   +8 more
openaire   +3 more sources

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Limb muscle mass and phase angle asymmetry in 8-year-old children

Scientific Reports
Little is known about phase angle (PhA), a bioelectrical impedance analysis (BIA) indicator of cellular health, and muscle asymmetry in the limbs of children. The purpose of this study is to clarify PhA and muscle mass asymmetry in the limbs of children.
Masanori Wako, Taro Fujimaki, Jiro Ichikawa, Ryoji Shinohara, Sanae Otawa, Anna Kobayashi, Megumi Kushima, Hideki Yui, Zentaro Yamagata, Hirotaka Haro, Yamanashi Adjunct Study of the Japan Environment, Children’s Study Group   +10 more
doaj   +1 more source

The stability of intelligence from age 11 to age 90 years:the Lothian birth cohort of 1921 [PDF]

, 2013
As a foundation for studies of human cognitive aging, it is important to know the stability of individual differences in cognitive ability across the life course. Few studies of cognitive ability have tested the same individuals in youth and old age.
Deary, Ian J, Starr, John M, Pattie, Alison   +2 more
core   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Syphilis-attributable adverse pregnancy outcomes in China: a retrospective cohort analysis of 1187 pregnant women with different syphilis treatment

BMC Infectious Diseases, 2019
Background Syphilis is responsible for a substantial burden of preventable adverse outcomes in pregnancy. The purpose of this study was to compare the frequency of adverse pregnancy outcomes among syphilis-seropositive women who received different ...
Huihui Liu, Niannian Chen, Jia Yu, Weiming Tang, Jianrong He, Huiyun Xiao, Suifang Lin, Fang Hu, Qiong Feng, Joseph D. Tucker, Huimin Xia, Xiu Qiu   +11 more
doaj   +1 more source

Alexithymic Traits and Hair Cortisol Concentrations in Pregnant Women

Frontiers in Psychiatry, 2020
IntroductionAlexithymia, a personality construct characterized by difficulties in identifying and expressing emotions, and an externally oriented thinking style, has been associated with a number of stress-related disorders, and physiological markers of ...
Jani Kajanoja, Jani Kajanoja, Jani Kajanoja, Max Karukivi, Max Karukivi, Max Karukivi, Paula Mustonen, Paula Mustonen, Noora M. Scheinin, Noora M. Scheinin, Susanna Kortesluoma, Ana João Rodrigues, Hasse Karlsson, Hasse Karlsson, Linnea Karlsson, Linnea Karlsson, Linnea Karlsson   +16 more
doaj   +1 more source

First birth trends in developed countries: a cohort analysis [PDF]

-cohort analysis, first ...
Jean-Paul Sardon, Tomas Frejka
core  

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Association between allergen-specific immunoglobulin E sensitization, allergic rhinitis symptoms, and quality of life in school-aged children

Scientific Reports
This study aimed to investigate the relationship between allergen-specific immunoglobulin E (IgE) sensitization and allergic rhinitis (AR) symptoms in school-aged children in Japan and to understand the current severity of AR symptoms and the quality of ...
Daisuke Watanabe, Sanae Otawa, Megumi Kushima, Hideki Yui, Ryoji Shinohara, Zentaro Yamagata, Daiju Sakurai, Kunio Miyake, The Yamanashi Adjunct Study of the Japan Environment and Children’s Study Group   +8 more
doaj   +1 more source