Results 91 to 100 of about 2,713,395 (314)

External validation of anti-Müllerian hormone based prediction of live birth in assisted conception [PDF]

open access: yes, 2013
<p>Background - Chronological age and oocyte yield are independent determinants of live birth in assisted conception. Anti-Müllerian hormone (AMH) is strongly associated with oocyte yield after controlled ovarian stimulation.
Alex McConnachie   +27 more
core   +2 more sources

Cell surface CD11c as a neutrophil aging marker molecule

open access: yesFEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki   +5 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

First birth trends in developed countries: a cohort analysis [PDF]

open access: yes
-cohort analysis, first ...
Jean-Paul Sardon, Tomas Frejka
core  

Don't birth cohorts matter? A commentary and simulation exercise on Reither, Hauser and Yang's (2009) age-period-cohort study of obesity [PDF]

open access: yes, 2013
Reither et al. (2009) use a Hierarchical Age-Period-Cohort model (HAPC - Yang & Land, 2006) to assess changes in obesity in the USA population. Their results suggest that there is only a minimal effect of cohorts, and that it is periods which have ...
Bell, Andrew   +5 more
core   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza   +19 more
wiley   +1 more source

Tempo-quantum and period-cohort interplay in fertility changes in Europe [PDF]

open access: yes
Using detailed data on period and cohort fertility in four European countries, this paper discusses various indicators of period fertility, including indicators adjusted for changes in fertility timing.
Tomas Sobotka
core  

Changes in BMI, Duration of Overweight and Obesity, and Glucose Metabolism: 45 Years of Follow-up of a Birth Cohort [PDF]

open access: yes, 2011
OBJECTIVE Long-term implications of childhood obesity and BMI change over the life course for risk of type 2 diabetes remain uncertain.
Claudia Thomas   +3 more
core   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

Child inhibitory control in toddlerhood: associations with child interaction skills with the mother

open access: yesBMC Psychology
Childhood inhibitory control (IC) is a key precursor of later social development, yet the mechanisms through which IC contributes to emerging interaction skills in toddlerhood remain insufficiently understood. We explored the cross-sectional associations
Pauliina Juntunen   +12 more
doaj   +1 more source

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