Results 31 to 40 of about 10,848,572 (295)
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Risk-taking middle-borns: A study on birth- order and risk preferences [PDF]
We analyze the impacts of birth order and presence/absence of siblings on risk preferences with respect to economic, health/safety, and sport/lifestyle related risks.
Lampi, Elina, Nordblom, Katarina
core +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Birth Order and Personality : Testing Assumptions with Independent Siblings' Reports [PDF]
Color poster with images, graphs, and tables.Assumptions about the effects of birth order on personality abound in popular culture, self-help books, and the scholarly literature.
Franklin, Bethany R. +2 more
core
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
A study of birth order and family characteristics in referrals to two UK primary school psychotherapy services [PDF]
Freud asserted that birth order should be considered in every life history assessment, yet birth order has been underinvestigated in the field of child psychotherapy and allied fields such as educational and developmental psychology. An overview of birth
MacDonald, Shelley +2 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Five Years International Workers Order: 1930–1935
A history of the first five years of the International Workers Order, addressing the IWO's foundation, its various ethnic sections, and its goals.CONTENTS: Five Years I.W.O. • First Struggles for Proletarian Order by R.
International Workers Order
core +4 more sources
The majority of screen time recommendations differ among parents of toddlers, preschoolers, and schoolchildren. In families with more than one child, it becomes more difficult for parents to apply these recommendations to each child individually because ...
Elena Chichinina +3 more
doaj +1 more source
Background: Having siblings may foster sociality; however, little is known about whether sibling number determines social capital, the resources obtained through social networks. We examined the association between sibling number and social capital among
Yukako Tani +3 more
doaj +1 more source

