Results 41 to 50 of about 2,070,255 (298)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Impact of New Living Environment on Reactive Stress Tolerance in Preadolescent Sports Trainees of Jharkhand

Physical Education Theory and Methodology, 2023
Study purpose. The purpose of the study was to examine the effect of background experience related to family demography on the selected parameters of reactive stress tolerance in athletes who strictly lived in a training academy for a minimum of two ...
Manohar Kumar Pahan, Vikrant Malhan, Yendrembam Nepoleon   +2 more
doaj   +1 more source

Birth Order Impacts: Real or Imagined? A Review of Literature Past and Present [PDF]

, 2012
The effect of birth order on a child’s development have long been the subject of research, with psychologists and biologists alike taking sides as to whether position in a family has real implications later in life. Studies have examined the consequences
Govek, Alexandra C
core   +1 more source

Russia’s Birth Rate Dynamics Forecasting [PDF]

, 2015
This article covers contemporary issues of Russia’s population reproduction, their causes and the state policy aimed to overcome the same. The urgency to fulfill the task related to assessment of the most probable future dynamics of Russia’s population ...
Bystray, G. P., Chichkanov, V. P., Okhotnikov, S. A., Vasilyeva, A. V.   +3 more
core   +3 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

BIRTH ORDER AND PSYCHIATRIC MORBIDITY

Khyber Medical University Journal, 2014
OBJECTIVES: 1. To determine the frequency of sociodemographic factors (birth order) among subjects attending a psychiatric clinic. 2. To establish psychiatric diagnosis of subjects. 3.
Fahad ul Zain, S Jamil Hussain, Fareeda Shaheen, Altaf Qadir, Jamil Junejo   +4 more
doaj  

Association Between Length of Only-Child Period During Early Childhood and Overweight at Age 8—A Population-Based Longitudinal Study in Japan

Frontiers in Pediatrics, 2022
IntroductionPrior studies have shown that children who are the only child are more likely to be overweight compared to their peers with siblings, regardless of whether they are the oldest, in the middle, or youngest.
Aomi Katagiri, Nobutoshi Nawa, Takeo Fujiwara   +2 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Generalized Fractional Nonlinear Birth Processes [PDF]

, 2015
We consider here generalized fractional versions of the difference-differential equation governing the classical nonlinear birth process. Orsingher and Polito (Bernoulli 16(3):858-881, 2010) defined a fractional birth process by replacing, in its ...
BEGHIN, Luisa, Davood Rostamy, Mohsen Alipour   +2 more
core   +1 more source