Results 81 to 90 of about 1,916,076 (342)
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Sub-registro de nascimentos vivos hospitalares em área urbana da região sul do Brasil, em 1989
Revista de Saúde PúblicaCom o objetivo de avaliar a real situação do Registro Civil, no Município de Maringá, PR, Brasil, foram estudados 4.876 nascimentos vivos ocorridos nos seus hospitais, em 1989, filhos de mulheres nele residentes. São apresentadas as etapas que permitiram
Regina K. Tanno de Souza +1 more
doaj
ECONOMICSThe purpose of the research work is to determine impact of the economic growth, digitization indicators and birth rate on female labor force in the Kazakhstan. For this purpose, Autoregressive Distributed Lag (ARDL) method was used.
Kakizhanova Tolkyn +4 more
doaj +1 more source
Цифровая социологияThe article is devoted to the study of the family institute and models of reproductive behaviour of the Russian population in the formation of a new sociо-gender order and demographic environment. The article considers the demographic situation in Russia,
G. G. Sillaste
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
ECONOMICSThe purpose of the research work is to assess the indicators of innovation, digitalization and knowledge that have an impact on the creative economy. For this purpose, the following indicators were analyzed: total GVA for the creative industry, the share
Bolatbek Yeldos +4 more
doaj +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
The impact of state agglomeration policy on long-term trends of population changes in Russia
RUDN Journal of Public AdministrationThe study analyzes the impact of state agglomeration policy on demographic trends in Russia, with a special focus on the relationship between urbanization and birth rate.
Arseniy M. Sitkovskiy
doaj +1 more source
THE EVOLUTION OF THE MAIN DEMOGRAPHIC PHENOMENA IN ROMANIA
Scientific Papers Animal Science and Biotechnologies, 2023 The trends of the main demographic phenomena provide useful information about the future evolution of the number and age structure of Romania’s population.
MANUELA-DORA ORBOI
doaj
GENDER DEMOGRAPHIC DISPARITIES IN BACAU COUNTY
Studies and Scientific Researches: Economics Edition, 2014 Gender demographic disparities existing in Bacau County were determined by means of some demographic indicators such as: population, natural growth, live births, marriages, divorces, indicators which have been broken down by gender. The assessment of the
Oana Ancuta Stangaciu, Eugenia Harja
doaj +1 more source