Results 41 to 50 of about 1,448,979 (308)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Pattern and Determinants of Birth Weight in a Rural Popula-tion of Punjab, India

open access: yesNational Journal of Community Medicine, 2017
Introduction: Birth weight is a strong predictor for ensuring healthy life of a newborn and is affected by various maternal and social determinants.
Mahesh Satija   +5 more
doaj  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Low birth weight and its association factors in Iran: according world health organization model

open access: yesJournal of Rehabilitation, 2012
Objective: Birth weight is one of the most important ,simplest and common determinations for assessments infants status in each country. this study has been designed to investigate the articles that published in its prevalence and related factors ...
zohreh Mahmoudi   +4 more
doaj  

Birth weight percentiles in Western-Mexico

open access: yesSalud Pública de México, 2022
Not ...
América Aime Corona-Gutiérrez   +6 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Association of Neonate’s Birth Weight with Material Weight Gain during Pregnancy

open access: yesJournal of Rawalpindi Medical College
Objective: To establish a relationship between maternal weight gain during pregnancy and a newborn’s birth weight. Method: A total of 120 patients were selected for this study.
Syeda Surayya Jabeen   +5 more
doaj   +1 more source

Estimated dietary iodine intake as a predictor of placental size: evidence from the ELSPAC study

open access: yesNutrition & Metabolism, 2018
Background The relationship between low iodine status and pregnancy-associated comorbidities has been known for decades. The relationship between iodine intake and placental pathologies is, however, far less clear.
Julie Bienertová-Vašků   +7 more
doaj   +1 more source

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