Results 141 to 150 of about 2,355 (158)

Comparative antiulcer effect of Bisdemethoxycurcumin and Curcumin in a gastric ulcer model system

Phytomedicine, 2009
The antiulcer effect of bisdemethoxycurcumin, a yellow pigment found mainly in rhizomes of Curcuma longa, was compared with curcumin in gastric ulcer model systems to validate its clinical application as a remedy for peptic ulcer. Western blot analysis of mouse macrophage cell line RAW 264.7 activated with lipopolysaccharide showed that ...
S, Mahattanadul, T, Nakamura, P, Panichayupakaranant, N, Phdoongsombut, K, Tungsinmunkong, P, Bouking   +5 more
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Novel osmium(ii)–cymene complexes containing curcumin and bisdemethoxycurcumin ligands

Inorganic Chemistry Frontiers, 2019
First examples of p-cymene-osmium(ii) curcuminoid complexes with antitumor activity.
Riccardo Pettinari, Fabio Marchetti, Corrado Di Nicola, Claudio Pettinari, Massimiliano Cuccioloni, Laura Bonfili, Anna Maria Eleuteri, Bruno Therrien, Lucinda K. Batchelor, Paul J. Dyson   +9 more
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Promising anti‐tumor properties of bisdemethoxycurcumin: A naturally occurring curcumin analogue

Journal of Cellular Physiology, 2017
Curcuminoids are turmeric‐extracted phytochemicals with documented chemopreventive and anti‐tumor activities against several types of malignancies. Curcuminoids can modulate several molecular pathways and cellular targets involved in different stages of tumor initiation, growth, and metastasis.
Mahin, Ramezani, Mahdi, Hatamipour, Amirhosein, Sahebkar   +2 more
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[Study on stability of curcumine, demethoxycurcumin and bisdemethoxycurcumin].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2009
To investigate the stability of curcumin, demethoxycurcumin and bisdemethoxycurcumin in different buffer solution.To determine concentration of curcumin by HPLC when added curcumin, demethoxycurcumin and bisdemethoxycurcumin into the buffer solution the equation of degradation was established.The sequence of stability are bisdemethoxycurcumin > or ...
Gang, Han, Jing-jing, Cui, Rui, Bi, Lin-lin, Zhao, Wei-guo, Zhang   +4 more
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Bisdemethoxycurcumin protects against renal fibrosis via activation of fibroblast apoptosis

European Journal of Pharmacology, 2019
Renal fibrosis is the common final outcome of nearly all progressive chronic kidney diseases (CKD) that eventually develop into end-stage renal failure, which threatens the lives of patients. Currently, there are no effective drugs for the treatment of renal fibrosis.
Fuquan, Jin, Ying, Jin, Jiangxia, Du, Liyu, Jiang, Ying, Zhang, Ziying, Zhao, Bo, Yang, Peihua, Luo, Qiaojun, He   +8 more
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Curcumin, demethoxycurcumin and bisdemethoxycurcumin differentially inhibit morphine's rewarding effect in rats

Psychopharmacology, 2014
Recent animal studies reported that curcumin, the active constituent of Curcuma longa, has several central actions and may attenuate morphine tolerance.In the present study, we utilized the intracranial self-stimulation (ICSS) paradigm to examine the effects of the commercially available curcuminoid mixture and each one of its components, individually,
Vicky, Katsidoni, Polyxeni, Alexiou, Marilena, Fotiadou, Maria, Pelecanou, Marina, Sagnou, George, Panagis   +5 more
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Separation and determination of the physico-chemical characteristics of curcumin, demethoxycurcumin and bisdemethoxycurcumin

Food Research International, 2005
The objective of this work was to separate and determine the physico-chemical and color characteristics of isolated curcuminoid pigments. Thin-layer chromatographic separation of curcuminoid pigments was possible on silica gel 60G plates using dichloromethane:methanol, 99:1.
L. Péret-Almeida, A.P.F. Cherubino, R.J. Alves, L. Dufossé, M.B.A. Glória   +4 more
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Comparison of suppressive effects of demethoxycurcumin and bisdemethoxycurcumin on expressions of inflammatory mediators In Vitro and In Vivo

Archives of Pharmacal Research, 2008
Demethoxycurcumin and bisdemethoxycurcumin are the main active ingredients isolated from Curcumae Longae Radix. Recent studies demonstrated that both compounds exhibit antioxidative and anti-inflammatory effects as well as effects on cancer cell lines.
Lian Yu, Guo, Xing Fu, Cai, Jung Joon, Lee, Sam Sik, Kang, Eun Myoung, Shin, Hong Yu, Zhou, Ji Won, Jung, Yeong Shik, Kim   +7 more
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Insights into inhibitory action and interaction of bisdemethoxycurcumin on tyrosinase: Spectroscopic and docking analysis

International Journal of Biological Macromolecules
Bisdemethoxycurcumin (BDMC), a demethoxy derivative of curcumin, has garnered interest for its potential anti-tyrosinase properties, which are crucial for applications in food preservation and cosmetic industries. Despite its recognized bioactive effects, the detailed inhibitory action and interaction of BDMC on tyrosinase and its application in anti ...
Xiaofeng, Min, Zhicheng, Su, Huan, Zhou, Xianke, Kou, Dongli, Li, Xuetao, Xu   +5 more
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Development and characterization of bisdemethoxycurcumin-loaded solid lipid nanoparticles

The aim of study was to develop solid lipid nanoparticles containing bisdemethoxycurcumin using rice bran wax compared to glyceryl behenate and cetyl palmitate for pharmaceutical application. Rice bran wax is a by-product from rice bran oil refinery. It contains potent antioxidant of gamma oryzanol utilized in pharmaceuticals. Solid lipid nanoparticles
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