Results 41 to 50 of about 57,075 (250)

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Scintillation properties of ((CH3)4N)3BiCl6 as a novel lead-free perovskite halide crystal

open access: yesMaterials Research Express, 2022
Two-dimensional hybrid organic-inorganic perovskites (2D-HOIPs) possess intriguing structural properties which makes them promising materials for diverse optical, electronic and scintillation applications.
Riki Subagyo   +9 more
doaj   +1 more source

BISMUTH AS AN ANTISEITIC [PDF]

open access: yesThe American Journal of the Medical Sciences, 1886
n ...
openaire   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Ionothermal Synthesis of Sulfidobismuth spiro‐Dicubane Cations

open access: yesChemistryOpen, 2022
Bi2S3 was dissolved in the presence of NaCl in the ionic liquid [BMIm]Cl ⋅ 4AlCl3 (BMIm=1‐n‐butyl‐3‐methylimidazolium) through annealing the mixture at 180 °C.
Maximilian Knies   +1 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Progress and perspectives of bismuth oxyhalides in catalytic applications

open access: yes, 2021
Bismuth oxyhalides are characterized by their open two-dimensional layered crystalline structures which endow bismuth oxyhalides with high specific surface areas, large amount of surface exposed atoms and some other unique physical and chemical ...
Wang, Li   +9 more
core   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

Bridging Cultures, Leading Peace: Leadership and Interculturalism in the Israel-Egypt Peace Negotiations

open access: yesStudia Universitatis Babeş-Bolyai. Studia Europaea
The 1979 peace treaty between Israel and Egypt marked a historic turning point in Middle Eastern diplomacy, establishing the first formal recognition of Israel by an Arab state.
Boaz BISMUTH
doaj   +1 more source

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