Results 41 to 50 of about 23,362 (196)

Drug poisonings following bariatric surgery: Case series report

British Journal of Clinical Pharmacology, EarlyView.
Bariatric surgery alters gastrointestinal anatomy and physiology, which likely impacts upon oral medication absorption. Drug‐ and alcohol‐related deaths in this population are being increasingly reported; however, toxicological detail is lacking. Using data reported to the National Programme on Substance Use Mortality, we identified 18 deaths in people
Eman Mshari, Fannie LaJeunesse‐Trempe, Stephen Morley, Caroline Copeland   +3 more
wiley   +1 more source

Comparative Analysis of Compendial Requirements for the Quality of Bisoprolol Products

Регуляторные исследования и экспертиза лекарственных средств
INTRODUCTION. Beta-blockers are one of the major groups of medicines used to treat cardiovascular diseases. Bisoprolol fumarate is of particular interest as it shows high selectivity towards beta-1 receptors.
O. A. Matveeva, E. L. Kovaleva, A. P. Karpushina, V. V. Akopova   +3 more
doaj   +1 more source

Kajian Interaksi Obat pada Pengobatan Diabetes Melitus (Dm) dengan Hipertensi di Instalasi Rawat Jalan RSUD Undata Periode Maret-juni Tahun 2014 [PDF]

, 2015
One of the chronic complications of diabetes mellitus is a disorder of macrovascular as hypertension so that in it's medicinal treatment required therapy with multiple drugs all at once that can lead to drug interactions.
Faustine, I. (Ingrid), Mukaddas, A. (Alwiyah), Nurlaelah, I. (Ida)   +2 more
core   +2 more sources

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Chromosomal Region 11p14.1 is Associated with Pharmacokinetics and Pharmacodynamics of Bisoprolol

Pharmacogenomics and Personalized Medicine, 2022
Vanessa Fontana,1,2 Richard Myles Turner,1,2 Ben Francis,3 Peng Yin,3 Benno Pütz,4 Timo P Hiltunen,5 Sanni Ruotsalainen,6 Kimmo K Kontula,5 Bertam Müller-Myhsok,1,4 Munir Pirmohamed1,2,7 1The Wolfson Centre for Personalised Medicine, Institute of ...
Fontana V, Turner RM, Francis B, Yin P, Pütz B, Hiltunen TP, Ruotsalainen S, Kontula KK, Müller-Myhsok B, Pirmohamed M   +9 more
doaj  

Novel selective β1-adrenoceptor antagonists for concomitant cardiovascular and respiratory disease [PDF]

, 2017
β-Blockers reduce mortality and improve symptoms in people with heart disease. However, current clinically available β-blockers have poor selectivity for the cardiac β1-adrenoceptor (AR) over the lung β2-AR.
Australian and Swedish Pindolol Study Group, Barrie Kellam, Bell D. S. H., Black J. W., Christophe Fromont, CIBIS‐II, Finlayson K., Gopal P. Jadhav, Hjalmarson A., Jeanette Woolard, Jillian G. Baker, Kevin S. J. Thompson, Leopold G., Lombardo F., Morales D. R., Odeh M., Peter M. Fischer, Schliep H. J., Shailesh N. Mistry, Sheila M. Gardiner, Stephen J. Hill, Valko K., Williams I. P., Xamoterol in Severe Heart Failure Study Group   +23 more
core   +1 more source

The quantitative impact of metabolism‐inhibiting drugs on the occurrence of adverse drug reactions—A backward selection approach

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The quantitative effect of several inhibitory drugs on the development of adverse drug reactions (ADRs) is currently difficult to estimate. Our aim was to identify metabolic pathways, which, when inhibited, increase the risk for certain ADRs, and to use this system to consider comedication at individual level. Methods Data of a prospective
Judith Berres, Justyna Wozniak, Hannah Fölsch, Anja Knueppel‐Ruppert, Verena Graeff, Andrea Kriegisch‐Stumpf, Harald Dormann, Julia C. Stingl, Katja S. Just   +8 more
wiley   +1 more source

Protective Effects of Bisoprolol against Acute Exacerbation in Moderate-to-Severe Chronic Obstructive Pulmonary Disease [PDF]

, 2017
Although recent retrospective studies suggested that the use of β-blockers appears to help improve the mortality rate and decrease the rate of exacerbation in chronic obstructive pulmonary disease (COPD) patients with heart failure, the effects of β ...
Fujii, Utako, Ichihara, Eiki, Ichikawa, Hirohisa, Kanehiro, Arihiko, Kiura, Katsuyuki, Miyahara, Nobuaki, Morichika, Daisuke, Oda, Naohiro, Oze, Isao, Taniguchi, Akihiko, Tanimoto, Mitsune, Tanimoto, Yasushi   +11 more
core   +1 more source

Cardiac remodelling in the era of the recommended four pillars heart failure medical therapy

ESC Heart Failure, Volume 12, Issue 2, Page 1029-1044, April 2025.
Abstract Cardiac remodelling is a key determinant of worse cardiovascular outcome in patients with heart failure (HF) and reduced ejection fraction (HFrEF). It affects both the left ventricle (LV) structure and function as well as the left atrium (LA) and the right ventricle (RV).
Giada Colombo, Tor Biering‐Sorensen, Joao P. Ferreira, Carlo Mario Lombardi, Andrea Bonelli, Andrea Garascia, Marco Metra, Riccardo M. Inciardi   +7 more
wiley   +1 more source

Use of the oral beta blocker bisoprolol to reduce the rate of exacerbation in people with chronic obstructive pulmonary disease (COPD): a randomised controlled trial (BICS)

Trials, 2022
Background Chronic obstructive pulmonary disease (COPD) is associated with significant morbidity, mortality and healthcare costs. Beta blockers are well-established drugs widely used to treat cardiovascular conditions.
Seonaidh Cotton, Graham Devereux, Hassan Abbas, Andrew Briggs, Karen Campbell, Rekha Chaudhuri, Gourab Choudhury, Dana Dawson, Anthony De Soyza, Shona Fielding, Simon Gompertz, John Haughney, Chim C. Lang, Amanda J. Lee, Graeme MacLennan, William MacNee, Kirsty McCormack, Nicola McMeekin, Nicholas L. Mills, Alyn Morice, John Norrie, Mark C. Petrie, David Price, Philip Short, Jorgen Vestbo, Paul Walker, Jadwiga Wedzicha, Andrew Wilson, Brian J. Lipworth   +28 more
doaj   +1 more source