Results 91 to 100 of about 1,538 (221)

Pharmacotherapy causing weight gain and metabolic alteration in those with obesity and obesity‐related conditions: A review

open access: yesAnnals of the New York Academy of Sciences, Volume 1533, Issue 1, Page 145-155, March 2024.
This review explores the diverse pathways by which various medications contribute to the pathophysiology of obesity. From antipsychotics and antihypertensives to steroids and insulin, we dissect the mechanisms causing weight gain and metabolic shifts in those with obesity who are taking pharmacotherapy for a range of obesity‐related conditions ...
Chika V. Anekwe   +3 more
wiley   +1 more source

Trends in medication use at the onset of and during the COVID‐19 pandemic in the Republic of Ireland: An interrupted time series study

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 134, Issue 2, Page 231-240, February 2024.
Abstract The COVID‐19 pandemic had a substantial impact on healthcare delivery, particularly in general practice. This study aimed to evaluate how dispensing of medications in primary care in Ireland changed following the COVID‐19 pandemic's onset compared to expected trends.
Molly Mattsson   +4 more
wiley   +1 more source

An In-Depth Examination of Formularies and Other Features of Medicare Drug Plans [PDF]

open access: yes, 2006
Provides a detailed assessment of the formularies, drug costs, and utilization management tools offered by the fourteen nationwide organizations that account for most of the stand-alone prescription drug ...
Elizabeth Hargrave   +3 more
core  

Affordability of Original and Generic Antihypertensive Drugs Under the National Centralized Drug Procurement Policy and Basic Medical Insurance System: A Cross‐Sectional Survey in Xi’an, China

open access: yesInternational Journal of Clinical Practice, Volume 2024, Issue 1, 2024.
Chinese government had implemented 8 rounds of National Centralized Drug Procurement (NCDP) in mainland China from 2019 to 2023. The purpose of this study is to assess the affordability profile and variation of policy‐related antihypertensive drugs in the context of NCDP, generic substitution, and basic medical insurance policy pre‐NCDP (in 2018) and ...
Yamin Zou   +6 more
wiley   +1 more source

A non-imaging high throughput approach to chemical library screening at the unmodified adenosine-A3 receptor in living cells [PDF]

open access: yes, 2017
Recent advances in fluorescent ligand technology have enabled the study of G protein-coupled receptors in their native environment without the need for genetic modification such as addition of N-terminal fluorescent or bioluminescent tags.
Antonioli   +59 more
core   +1 more source

CONFORMATIONAL LANDSCAPE AND UV-VIS SPECTRUM OF S-BISOPROLOL [PDF]

open access: yes, 2016
The conformational changes of bisoprolol (BISO) are crucial for understanding its interaction with the receptor and the mechanism of action. Therefore, here we investigated the free energy conformational landscape of the free bisoprolol base, aiming at ...
CHIŞ, Vasile, VINŢELER, Emil
core   +1 more source

Efficacy and safety of low-dose bisoprolol/hydrochlorothiazide combination for the treatment of hypertension: a systematic review and meta-analysis [PDF]

open access: yes
Objectives: This systematic review and meta-analysis aimed to assess the blood pressure (BP)-lowering effect and the safety profile of low-dose bisoprolol/hydrochlorothiazide combination treatment in patients with hypertension.
ALGhasab, Naif Saad   +5 more
core   +4 more sources

A HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY–MASS SPECTROMETRY/MASS SPECTROMETRY METHOD DEVELOPMENT FOR THE QUANTITATIVE DETERMINATION OF BISOPROLOL FROM CACO-2 CELL MONOLAYERS [PDF]

open access: yes, 2018
 Objective: A simple, rapid high-performance liquid chromatography–mass spectrometry (MS)/MS method was developed for the determination of bisoprolol from confluent Caco-2 monolayers and from aqueous solution.Methods: Chromatography was achieved on ...
Korobko, Dmytro, Logoyda, Liliya
core   +1 more source

Розробка методу ідентифікації одночасного визначення амлодипіну, каптоприлу та бісопрололу в лікарських формах [PDF]

open access: yes, 2017
Topicality. During the sample preparation and chromatographic separation thin layer chromatography (TLC) plays important role. Thin layer chromatography, or TLC, is a method for analyzing mixtures by separating the compounds in the mixture.
Logoyda, L. S.
core   +2 more sources

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