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Current Computer-Aided Drug Design
Background: An important characteristic of the quality-by-design approach is defining risk, which is a combination of the probability of harm and its severity. During risk assessment, it is essential to determine how the formulation, properties of active ingredients and excipients, and process parameters can ...
Nadia Malanchuk +3 more
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Background: An important characteristic of the quality-by-design approach is defining risk, which is a combination of the probability of harm and its severity. During risk assessment, it is essential to determine how the formulation, properties of active ingredients and excipients, and process parameters can ...
Nadia Malanchuk +3 more
openaire +2 more sources
Preparation of bisoprolol fumarate nasal spray and its nasal delivery in rats.
Pakistan journal of pharmaceutical sciences, 2016The aim of the present work was to prepare a nasal spray of bisoprolol fumarate (BF). The Pharmacokinetics and relative bioavailability of the BF nasal formulation were evaluated in Wistar rats. The BF nasal spray after administration exhibited very fast absorption and higher plasma drug concentration.
Gu, Fugen +4 more
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Pakistan journal of pharmaceutical sciences, 2008
Two analytical methods have been developed for simultaneous quantification of bisoprolol fumarate and hydrochlorothiazide in combined pharmaceutical dosage form using spectrophotometer. Excellent simplicity, accuracy, precision and economy were achieved by the assay.
Shirkhedkar Atul, A +2 more
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Two analytical methods have been developed for simultaneous quantification of bisoprolol fumarate and hydrochlorothiazide in combined pharmaceutical dosage form using spectrophotometer. Excellent simplicity, accuracy, precision and economy were achieved by the assay.
Shirkhedkar Atul, A +2 more
openaire +1 more source