Results 91 to 100 of about 34,210 (202)

A HPLC-MS/MS METHOD DEVELOPMENT AND VALIDATION FOR THE SIMULTANEOUS DETERMINATION OF BISOPROLOL AND ENALAPRIL IN THE PRESENT OF ENALAPRILAT IN HUMAN PLASMA

open access: yes, 2018
Objective: A highly specific, sensitive and rapid HPLC-MS/MS method has been developed and validated for the simultaneous quantification of bisoprolol and enalapril in the present of enalaprilat in human plasma.Methods: Analytes were extracted from ...
Korobko, Dmytro   +9 more
core   +1 more source

Desirability Based Optimization and Validation of New RP-HPLC Method for Simultaneous Determination of Bisoprolol Fumarate, Hydrochlorothiazide and Their Impurities

open access: yes, 2016
In this paper optimization and validation of a new RP-HPLC method for simultaneous determination of bisoprolol fumarate, hydrochlorothiazide and impurities A, L, K and B are presented.
Vulović-Tadić, Miljana   +4 more
core   +1 more source

Investigation of Metoprolol Concentrations in Plasma Using Automated Sample Preparation and LC-MS/MS Detection

open access: yesSeparations
Metoprolol (MTP), a selective beta-1 adrenergic blocker, is commonly administered in the form of succinate or tartrate salts, depending on the pharmaceutical formulation.
Ionel-Bogdan Cioroiu   +4 more
doaj   +1 more source

Etude de la Sécabilité de trois génériques de Bisoprolol Fumarate 5 mg

open access: yes, 2017
La précision de la sécabilité des comprimés de trois génériques de Bisoprolol Fumarate a été étudiée par l’analyse des variations de masse et de teneur en principe actif des comprimés entiers et des demi-comprimés.
Hassane, SAADOUN, Merouane, YOUNSI
core  

UEG Week 2025 Poster Presentations

open access: yes
United European Gastroenterology Journal, Volume 13, Issue S8, Page S803-S1476, October 2025.
wiley   +1 more source

A case of reinitiation of modified electroconvulsive therapy 2 weeks after modified electroconvulsive therapy‐induced Takotsubo cardiomyopathy in a male patient with major depressive disorder

open access: yesPCN Reports
Background Takotsubo cardiomyopathy (TCM) is a left ventricular dysfunction resembling acute coronary syndrome. Its prognosis is generally favorable; however, a subset of patients may present with severe complications.
Dai Kezuka   +3 more
doaj   +1 more source

Analytical High Performance Liquid Chromatography Method for Estimation of the Bisoprolol Fumarate

open access: yes
Introduction: Quality by Design (QbD) guidelines from ICH address pharmaceutical drug ingredient and product research, method development, and validation. Analytical techniques aid QbD application in pharmaceutical development, manufacturing, and quality
Deepak Pokharkar, Gouri Palsokar, Amol Kokane, Nikita Shintre, Himeya Mhatre, Harsh Mehta
core  

Development, Optimization and Evaluation of Bisoprolol Fumarate Loaded Self Emulsifying Drug Delivery System

open access: yes
In the current research, a Bisoprolol Fumarate-loaded Self-Emulsifying Drug Delivery System (SEDDS) was developed to enhance the solubility and bioavailability of the drug, aiming to overcome its pharmacokinetic limitations.
Chandra Kishor Tyagi, Anish Rathi, Bharat Kumar Tyagi, Atul Tripathi
core  

Обоснование выбора условий определения родственных примесей методом ВЭЖХ в фармацевтической субстанции бисопролола фумарат

open access: yes, 2018
The article summarizes the results of information analysis of bisoprolol fumarate synthesis methods which differ in the number of stages and in raw materials used, and are associated with the major identified impurities A, E and G, according to the ...
Т. Н. Боковикова   +15 more
core  

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