Results 51 to 60 of about 744 (160)

Synaptic Targets and Cellular Sources of CB1 Cannabinoid Receptor and Vesicular Glutamate Transporter‐3 Expressing Nerve Terminals in Relation to GABAergic Neurons in the Human Cerebral Cortex

European Journal of Neuroscience, Volume 61, Issue 1, January 2025.
In the human cerebral cortex, GABAergic boutons originating from diverse presynaptic cell types, some expressing CB1 cannabinoid receptor, make synapses mainly with dendritic shafts and spines. One quarter of GABAergic CB1 immunopositive nerve terminals also expresses the type 3 vesicular glutamate transporter (VGLUT3).
Peter Somogyi, Sawa Horie, Istvan Lukacs, Emily Hunter, Barbara Sarkany, Tim James Viney, James Livermore, Puneet Plaha, Richard Stacey, Olaf Ansorge, Salah El Mestikawy, Qianru Zhao   +11 more
wiley   +1 more source

Buspirone Hydrochloride Polymorphism: Stability, Solubility, Flow Properties, and Manufacturing Implications

Advances in Pharmacological and Pharmaceutical Sciences, Volume 2025, Issue 1, 2025.
Buspirone hydrochloride, an anxiolytic agent, has two interconvertible polymorphic forms that may affect its physicochemical properties and therapeutic efficacy. Despite this relevance, polymorphism is often neglected in pharmaceutical analyses, potentially leading to inconsistent results and compromised drug performance.
Jéssika Adriane Janning, Victória Guimarães Santiago, Ederlan de Souza Ferreira, Carolina Oliveira de Souza, Márcia Nunes da Silva, Filipa Sofia Reis, Nelson Barros Colauto, Renato Eising, Ghulam Hussain   +8 more
wiley   +1 more source

Successful Use of Remimazolam in a Dialysis Patient With End‐Stage Renal Disease and a History of Cardiac Arrest Following Induction of Propofol Anesthesia: A Case Report

Case Reports in Anesthesiology, Volume 2025, Issue 1, 2025.
Background: Remimazolam, an ultra‐short‐acting benzodiazepine, has minimal hemodynamic impact compared with propofol, making it a potentially safer alternative for patients at high cardiovascular risk. This report highlights the anesthetic management of a hemodialysis patient with end‐stage renal disease who had a prior cardiac arrest induced by ...
Toshihiro Takeda, Koji Okano, Yuichi Ogino, Anjan Trikha   +3 more
wiley   +1 more source

Development and validation of a RP-HPLC method for simultaneous determination of Dapagliflozin propanediol monohydrate and Bisoprolol fumarate in Pharmaceutical Dosage form

Drug Analytical Research
The purpose of this study was to develop a new method for simultaneously determining the presence of Dapagliflozin propanediol monohydrate (DAPA) and Bisoprolol Fumarate (BISO) in a tablet formulation using reverse-phase high-performance liquid ...
Dhara Patel, Khyati Shah, Grishma Patel, Dhananjay Meshram   +3 more
doaj   +3 more sources

Method development and validation for simultaneous estimation of dapagliflozin and bisoprolol by using stability-indicating RP-HPLC

Discover Chemistry
A fixed-dose combination of dapagliflozin and bisoprolol is used to treat type 2 diabetes mellitus and can also help to manage blood pressure and cardiovascular risks.
Rajendra Patel, Nishith Teraiya, Soni Diya   +2 more
doaj   +1 more source

Tools for clinical pharmacists to identify medications that can cause drug‐induced cognitive impairment: A systematic review

JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 7, Issue 12, Page 1207-1227, December 2024.
Abstract Cognitive impairment affects around 19% of community‐dwelling older adults in the United States. Pharmacists can play a significant role in identifying and deprescribing cognitive‐impairing medications through cognitive‐focused medication reviews or as part of comprehensive medication management.
Jacob Stanton, Michael R. Gionfriddo, Gail B. Rattinger, Yuan Fang, Mia E. Lussier   +4 more
wiley   +1 more source

Hydrodissection for pericardial adhesion in percutaneous epicardial ventricular tachycardia ablation

Journal of Arrhythmia, Volume 40, Issue 6, Page 1514-1518, December 2024.
Epicardial ablation in patients with pericardial adhesions is challenging. This case is the first report of successful epicardial ventricular tachycardia ablation by combining hydrodissection with the previously reported blunt dissection techniques for pericardial adhesions.
Yoshimi Onishi, Taku Asano, Shuhei Arai, Yuya Nakamura, Toshiro Shinke   +4 more
wiley   +1 more source

Transdermal bisoprolol for prevention of postoperative atrial fibrillation: A systematic review and meta‐analysis

Journal of Arrhythmia, Volume 40, Issue 3, Page 434-439, June 2024.
Transdermal bisoprolol effectively reduces postoperative atrial fibrillation, potentially outperforming oral formulations. Abstract Background The transdermal patch of bisoprolol available in Japan has been reported to demonstrate superior efficacy in preventing postoperative atrial fibrillation, possibly surpassing its oral counterpart. However, there
Andrew G. Kim, Sandeep Banga, Qi Xuan Ang, Lalitsiri Atti, Harith Ghnaima, Saif AlAttal, Preeti Banga, Matthew D. Wilcox   +7 more
wiley   +1 more source

Sodium-glucose co-transporter-2 inhibitor-associated non-diabetic ketoacidosis: a case report

Italian Journal of Medicine
Ketoacidosis is considered an emergency metabolic disorder that can be triggered by starvation and alcohol consumption in addition to diabetes. We described an unusual case of ketoacidosis in a non-diabetic young man who presented to our hospital with a
Vincenzo Trapanese, Francesco Maruca, Maria Resilde Natale, Federica Giofrè, Francesca Cosentino, Silvia Sergi, Giuseppe Armentaro, Valentino Condoleo, Franco Arturi   +8 more
doaj   +1 more source

Accelerated Intermittent Theta Burst Stimulation Combined with Balance Training Improves Balance in an Individual with Corticobasal Syndrome

Movement Disorders Clinical Practice, Volume 12, Issue 10, Page 1681-1683, October 2025.
Karishma R. Ramdeo, Stevie D. Foglia, Malaikah Ahmad, Nafia Al‐Mutawaly, Justin Lee, Robert Chen, Aimee J. Nelson   +6 more
wiley   +1 more source