Analytical Techniques for Determination of Hydrochlorothiazide and its Combinations: A Review [PDF]
Hydrochlorothiazide is chemically 6-chloro-1, 1-dioxo-3, 4-dihydro-2 H -1, 2, 4-benzothiadiazine-7-sulfonamide. Hydrochlorothiazide is a diuretic drug used for treatment of high blood pressure(hypertension) and accumulation of fluid (edema).
Raj, Hasumati A. +2 more
core +2 more sources
Dabigatran‐induced esophagitis with full circumferential blue pigmentation
Abstract Dabigatran is a useful and widely used drug for stroke prevention in patients with atrial fibrillation. However, it has been reported to cause esophagitis. Herein, we report the case of a 77‐year‐old man with dabigatran‐induced esophagitis with blue pigmentation, which is known to be a rare adverse effect. The patient presented to our hospital
Tomonori Araki +7 more
wiley +1 more source
A non-imaging high throughput approach to chemical library screening at the unmodified adenosine-A3 receptor in living cells [PDF]
Recent advances in fluorescent ligand technology have enabled the study of G protein-coupled receptors in their native environment without the need for genetic modification such as addition of N-terminal fluorescent or bioluminescent tags.
Antonioli +59 more
core +1 more source
The European List of Key Medicines for Medical Education: A Modified Delphi Study
Rational prescribing is essential for the quality of health care. However, many final‐year medical students and junior doctors lack prescribing competence to perform this task. The availability of a list of medicines that a junior doctor working in Europe should be able to independently prescribe safely and effectively without supervision could support
Erik M. Donker +198 more
wiley +1 more source
An In-Depth Examination of Formularies and Other Features of Medicare Drug Plans [PDF]
Provides a detailed assessment of the formularies, drug costs, and utilization management tools offered by the fourteen nationwide organizations that account for most of the stand-alone prescription drug ...
Elizabeth Hargrave +3 more
core
This review explores the diverse pathways by which various medications contribute to the pathophysiology of obesity. From antipsychotics and antihypertensives to steroids and insulin, we dissect the mechanisms causing weight gain and metabolic shifts in those with obesity who are taking pharmacotherapy for a range of obesity‐related conditions ...
Chika V. Anekwe +3 more
wiley +1 more source
MICROENCAPSULATION BISOPROLOL FUMARATE WITH EUDRAGIT E PO BY SOLVENT EVAPORATION METHOD
Objective: This study aimed to develop and optimize the microcapsule formula of bisoprolol fumarate-Eudragit EPO by double-emulsion solvent evaporation. Methods: The preparation of bisoprolol fumarate-Eudragit EPO microcapsule was done in three different ratios 1: 3 (F1), 1: 4 (F2), and 1: 5 (F3), followed by characterization of each of the ...
AZHOMA GUMALA +3 more
openaire +1 more source
CONFORMATIONAL LANDSCAPE AND UV-VIS SPECTRUM OF S-BISOPROLOL [PDF]
The conformational changes of bisoprolol (BISO) are crucial for understanding its interaction with the receptor and the mechanism of action. Therefore, here we investigated the free energy conformational landscape of the free bisoprolol base, aiming at ...
CHIŞ, Vasile, VINŢELER, Emil
core +1 more source
Efficacy and safety of low-dose bisoprolol/hydrochlorothiazide combination for the treatment of hypertension: a systematic review and meta-analysis [PDF]
Objectives: This systematic review and meta-analysis aimed to assess the blood pressure (BP)-lowering effect and the safety profile of low-dose bisoprolol/hydrochlorothiazide combination treatment in patients with hypertension.
ALGhasab, Naif Saad +5 more
core +4 more sources
A HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY–MASS SPECTROMETRY/MASS SPECTROMETRY METHOD DEVELOPMENT FOR THE QUANTITATIVE DETERMINATION OF BISOPROLOL FROM CACO-2 CELL MONOLAYERS [PDF]
 Objective: A simple, rapid high-performance liquid chromatography–mass spectrometry (MS)/MS method was developed for the determination of bisoprolol from confluent Caco-2 monolayers and from aqueous solution.Methods: Chromatography was achieved on ...
Korobko, Dmytro, Logoyda, Liliya
core +1 more source

