ABSTRACT Objectives Teclistamab and talquetamab treatments are typically initiated in a hospital due to the potential risk of cytokine release syndrome. However, emerging data support the potential for outpatient administration (i.e., administration without overnight hospital admission).
Thomas Lund+12 more
wiley +1 more source
Bispecific Antibodies in Solid Tumors: Advances and Challenges. [PDF]
Shan KS+7 more
europepmc +1 more source
Improved Pharmacokinetics of Recombinant Bispecific Antibody Molecules by Fusion to Human Serum Albumin [PDF]
Dafne Müller+5 more
openalex +1 more source
Vaccination in Multiple Myeloma: Challenges and Strategies
ABSTRACT Background Multiple myeloma (MM) is a hematological malignancy characterized by profound immunosuppression resulting from both disease‐related mechanisms and treatment‐induced immune dysfunction. This compromised immune status markedly increases susceptibility to infections, a leading cause of morbidity and mortality in MM patients.
Enrica Antonia Martino+10 more
wiley +1 more source
Exploring T-cell bispecific antibodies in gynecologic malignancy. [PDF]
O'Brien E, Mayer CM, Arend RC.
europepmc +1 more source
Bispecific anti-CD20/22 antibodies inhibit B-cell lymphoma proliferation by a unique mechanism of action [PDF]
Zhengxing Qu+5 more
openalex +1 more source
Extracellular vesicles in multiple myeloma: pathogenesis and therapeutic application
Multiple myeloma is characterised by the clonal proliferation of plasma cells in the bone marrow. Extracellular vesicles (EVs) are a key component of cell‐to‐cell communication within the bone marrow microenvironment, promoting tumour growth, bone remodelling, immune modulation, angiogenesis and therapeutic resistance.
Chloe Wylie+3 more
wiley +1 more source
Comprehensive assessment of adverse event profiles associated with bispecific antibodies in multiple myeloma. [PDF]
Golmohammadi M+14 more
europepmc +1 more source
Construction of Optimized Bispecific Antibodies for Selective Activation of the Death Receptor CD95 [PDF]
Tanja Herrmann+5 more
openalex +1 more source
Blood group O expression in normal tissues and tumors
The H antigen (O blood group), the precursor to A and B blood groups, is expressed on human erythrocytes. Two novel monoclonal antibodies generated using sea lamprey immunization, Tn4‐31L and OmcFL3‐02, specifically detect the H antigen on glycan microarrays, glycoproteins, and human cells.
Ea Kristine Clarisse Tulin+11 more
wiley +1 more source