Results 311 to 320 of about 1,468,461 (396)

Novel loop structure of human IgG1 Fc fused CD38 targeted bispecific antibodies and their anti-tumor effect in acute myeloid leukemia. [PDF]

J Transl Med
Wang S, Chen M, Zhou T, Guo C, Yan Z, Xu Y, Xing H, Tang K, Tian Z, Rao Q, Qiu S, Wang Y, Gu R, Wang M, Wang J.   +14 more
europepmc   +1 more source

The Development and Application of Bispecific Antibodies in B-Cell Non-Hodgkin Lymphoma. [PDF]

J Pers Med
Sun L, Romancik JT.
europepmc   +1 more source

Application and future prospects of bispecific antibodies in the treatment of non-small cell lung cancer. [PDF]

Cancer Biol Med
Wen J, Cui W, Yin X, Chen Y, Liu A, Wang Q, Meng X.   +6 more
europepmc   +1 more source

Screening of Theaflavins That Inhibit Proliferation of Nasopharyngeal Carcinoma Cells Through Metabolomics Approaches

Food Science &Nutrition, Volume 13, Issue 8, August 2025.
This study investigated the effects of theaflavin‐3,3′‐digallate (TF3) markedly suppresses the proliferation, migration, invasion of nasopharyngeal carcinoma cells while promoting apoptosis in a dose‐dependent manner. Metabolomic profiling identified 584 altered metabolites, revealing key disruptions in ABC transporter activity and amino acid ...
Chunpeng Wan, Xiaomeng Hu, Puxiang Yang, Mingxi Li, Muhammad Farrukh Nisar, Zihao Zhou, Yudi Gan, Yi Cai, Zhonghua Liu   +8 more
wiley   +1 more source

Harnessing the immunotherapeutic potentials of gamma delta T cells against hematological malignancies

HemaSphere, Volume 9, Issue 8, August 2025.
Abstract Gamma delta (γδ) T cells, which constitute about 5%–10% of peripheral blood lymphocytes, play key roles in tumor immunosurveillance and are often enriched within epithelial tissues. They are unique in their Major Histocompatibility Complex‐independent antigen recognition via the γδ T‐cell receptor (TCR) as well as via innate receptors, making ...
Charles Agbuduwe, John Maher, John Anderson   +2 more
wiley   +1 more source

New Frontiers in Multiple Sclerosis Treatment: From Targeting Costimulatory Molecules to Bispecific Antibodies. [PDF]

Int J Mol Sci
Reidy M, Khan M, Mills EA, Wu Q, Garton J, Draayer DE, Zahoor I, Giri S, Axtell RC, Mao-Draayer Y.   +9 more
europepmc   +1 more source

Inflammatory signaling in the pathogenesis of acute myeloid leukemia

HemaSphere, Volume 9, Issue 8, August 2025.
ABSTRACT Acute myeloid leukemia (AML) is a heterogeneous clonal disorder of hematopoietic stem and progenitor cells and the most common malignant myeloid disorder in adults. Extensive research has elucidated the broad spectrum of biological mechanisms contributing to the development of AML and specifically characterized a variety of genetic alterations
Artemis Margrith Baumann, Jana Maria Ellegast   +1 more
wiley   +1 more source

A new era in myeloma: the advent of chimeric antigen receptor-T (CAR-T) cells and bispecific antibodies. [PDF]

Intern Med J
Ho PJ, Li EW.
europepmc   +1 more source

Characteristics, Treatment Patterns, and Outcomes of Patients with Multiple Myeloma, Including Those Who are Triple‐Class Exposed: A Retrospective Cohort Study in England Using National Cancer Registry Data

eJHaem, Volume 6, Issue 4, August 2025.
ABSTRACT Introduction Multiple myeloma (MM) prognosis worsens once patients become triple‐class exposed (TCE) to at least one treatment in each class: immunomodulators, proteasome inhibitors, and anti‐CD38 monoclonal antibodies. Methods We conducted a retrospective study using the Cancer Analysis System database to assess characteristics, treatment ...
Carmen Tsang, Kellyn Arnold, Charles Duffield, Stavros Oikonomou, Thomas Price, Tarana Mehdikhanova, Samuel Wood, Mamta Garg   +7 more
wiley   +1 more source

Defining infection risk of bispecific antibodies for myeloma. [PDF]

Blood Adv
Hammond SP.
europepmc   +1 more source