Results 331 to 340 of about 1,468,461 (396)

Bispecific antibody targeting CD40 and HER2 potentiates therapeutic efficacy by reprogramming macrophages within the tumour microenvironment

Clinical and Translational Medicine, Volume 15, Issue 8, August 2025.
Na Li, Ruonan Li, Qiongqiong Ma, Xiaoqi Zhang, Wenxuan Ma, Yi Wang, Baoxin Duan, Kailu Yang, Dongping Zhang, Jiashuo Zhang, Manping Gu, Yaxing Wu, Jiajin Sun, Huawei Wang, Anqi Li, Fuquan Chen, Yiyang Bai, Yujie Tian, Xin Li, Yingbin Yan, Wei Wang, Hongkai Zhang, Yuan Wang   +22 more
wiley   +1 more source

Reversal of Endothelial Cell Anergy by T Cell-Engaging Bispecific Antibodies. [PDF]

Cancers (Basel)
Gonçalves M, Warwas KM, Meyer M, Schwartz-Albiez R, Bulbuc N, Zörnig I, Jäger D, Momburg F.   +7 more
europepmc   +1 more source

Design of orthogonal constant domain interfaces to aid proper heavy/light chain pairing of bispecific antibodies. [PDF]

MAbs
Barlow KA, Battles MB, Brown ME, Canfield K, Lu X, Lynaugh H, Morrill M, Rappazzo CG, Reyes SP, Sandberg C, Sharkey B, Strong C, Zhao J, Sivasubramanian A.   +13 more
europepmc   +1 more source

Metabolic Engineering of Glycofusion Bispecific Antibodies for α-Dystroglycanopathies. [PDF]

Antibodies (Basel)
Zhong X, Yan GG, Chaturvedi A, Li X, Gao Y, Girgenrath M, Corcoran CJ, Diblasio-Smith L, LaVallie ER, de Rham T, Zhou J, Abel M, Riegel L, Lim SKH, Bloom L, Lin L, D'Antona AM.   +16 more
europepmc   +1 more source

Bispecific antibodies

Drug Discovery Today, 2021
Bispecific antibodies have emerged as molecules with a multitude of talents Bispecific antibodies (bsAbs) bind two different epitopes on the same or different antigens.
U. Brinkmann, R. Kontermann
semanticscholar   +4 more sources

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Bispecific antibodies in oncology

Nature Reviews Drug Discovery, 2022
A. Esfandiari, Sorcha A. Cassidy, Rachel M. Webster   +2 more
semanticscholar   +3 more sources

Bispecific Antibodies for the Treatment of Neuroblastoma

SSRN Electronic Journal, 2022
Bispecific antibodies (BsAb) are a new generation of antibody-based therapy, conveying artificial specificity to polyclonal T cells or radiohaptens. These drugs have been successfully implemented to cure hematologic malignancies and are under clinical investigation for solid tumors including HRNB.
Madelyn, Espinosa-Cotton, Nai-Kong V, Cheung   +1 more
openaire   +2 more sources

Bispecific Antibodies in Lymphoma

International Reviews of Immunology, 1993
Journal Article ; Review ; SCOPUS: ar.j ; info:eu-repo/semantics ...
Brissinck, J, Demanet, Christian, Moser, Muriel, Leo, Oberdan, Thielemans, Kris   +4 more
openaire   +3 more sources

Engineering bispecific antibodies

Current Opinion in Biotechnology, 1993
Bispecific antibodies have immense potential as reagents and in medicine. Until recently, they were made by combining monoclonal antibodies of two different specificities in vitro, or by fusion of the corresponding hybridomas. Protein engineering now offers the chance to construct a range of small 'designer' bispecific antibodies using antibody ...
Philipp Holliger, Greg Winter
openaire   +3 more sources