Results 251 to 260 of about 1,443,667 (357)

Acute Myeloid Leukemia: 2025 Update on Diagnosis, Risk‐Stratification, and Management

American Journal of Hematology, Volume 100, Issue 5, Page 860-891, May 2025.
ABSTRACT Disease Overview Acute myeloid leukemia (AML) is a bone marrow stem cell cancer that is often fatal despite available treatments. Diagnosis, risk assessment, monitoring, and therapeutic management of AML have changed dramatically in the last decade due to increased pathophysiologic understanding, improved assessment technology, and the ...
Shai Shimony, Maximilian Stahl, Richard M. Stone   +2 more
wiley   +1 more source

Effect of Intravenous Immunoglobulin (IVIG) Supplementation on infection-free survival in recipients of BCMA-directed bispecific antibody therapy for multiple myeloma. [PDF]

Blood Cancer J
Mohan M, Szabo A, Cheruvalath H, Clennon A, Bhatlapenumarthi V, Patwari A, Balev M, Bhutani D, Shrestha A, Thanendrarajan S, Dhakal B, Zangari M, Trikannad A, Vellanki S, Al-Hadidi S, Lentzsch S, van Rhee F, Bag A, D'Souza A, Shah N, Chakraborty R, Shah MR, Schinke C.   +22 more
europepmc   +1 more source

Synthesis and Evaluation of an Anti-MLC1 × Anti-CD90 Bispecific Antibody for Targeting and Retaining Bone-Marrow-Derived Multipotent Stromal Cells in Infarcted Myocardium [PDF]

, 2011
C. William Gundlach, Amy R. Caivano, Maria da Graça Cabreira-Hansen, Amir Gahremanpour, Wells S. Brown, Yi Zheng, Bradley W. McIntyre, James T. Willerson, Richard A. F. Dixon, Emerson C. Perin, Darren G. Woodside   +10 more
openalex   +1 more source

NK cell depletion in bispecific antibody therapy is associated with lack of HIV control after ART interruption. [PDF]

Commun Biol
Sánchez-Gaona N, Perea D, Curran A, Burgos J, Navarro J, Suanzes P, Falcó V, Martín-Gayo E, Genescà M, Carrillo J, Buzón MJ.   +10 more
europepmc   +1 more source

Bispecific Antibody Pretargeting for Improving Cancer Imaging and Therapy

, 2005
Robert M. Sharkey
openalex   +2 more sources

Alternative Immunosuppression in Acquired Haemophilia A

Haemophilia, EarlyView.
Jayna Mistry, Gillian Lowe, Will Lester, Charles Percy   +3 more
wiley   +1 more source

Novel Trispecific Neutralizing Antibodies With Enhanced Potency and Breadth Against Pan‐Sarbecoviruses

MedComm, Volume 6, Issue 5, May 2025.
Multispecific antibodies harness the advantages of two or more mAbs. In this study, we designed novel trispecific antibodies, Tri‐1 and Tri‐2, derived from our previously identified mAbs, PW5‐5, PW5‐535, and PW5‐570. These trispecific antibodies exhibited enhanced binding affinity and broad neutralization capacity against SARS‐CoV, SARS‐CoV‐2 variants,
Rui Qiao, Yuanchen Liu, Qiyu Mao, Jiayan Li, Yinying Lu, Jialu Shi, Chen Li, Jizhen Yu, Jiami Gong, Xun Wang, Yuchen Shao, Lei Sun, Wenhong Zhang, Hongjie Yu, Hin Chu, Pengfei Wang, Xiaoyu Zhao   +16 more
wiley   +1 more source

A B7-H3-Targeted CD28 Bispecific Antibody Enhances the Activity of Anti-PD-1 and CD3 T-cell Engager Immunotherapies. [PDF]

Mol Cancer Ther
Moore GL, Zeng VG, Diaz JE, Bonzon C, Avery KN, Rashid R, Qi J, Nam DH, Jacinto J, Dragovich MA, Kim YK, Balcazar KP, Bakhit CG, Eivazi A, Nguyen H, Muchhal US, Szymkowski DE, Desjarlais JR, Hedvat M.   +18 more
europepmc   +1 more source

Targeted delivery of radioisotope or chemotherapeutic loaded prodrug-polymers after pretargeting tumors with bispecific antibody complex [PDF]

, 2011
Keyur Gada
openalex   +1 more source

Ethnic Sensitivity Assessment of Mosunetuzumab Pharmacokinetics and Pharmacodynamics in Chinese Patients With Relapsed or Refractory Follicular Lymphoma

Clinical and Translational Science, Volume 18, Issue 5, May 2025.
ABSTRACT Mosunetuzumab, a CD20 × CD3 T‐cell‐engaging bispecific antibody, redirects T cells to eliminate malignant B cells. The purpose of YO43555 was to assess the pharmacokinetics (PK), safety, tolerability, and efficacy of mosunetuzumab as a single agent in Chinese patients with relapsed/refractory follicular lymphoma (R/R FL).
Junyi Li, Michael Z. Liao, Justin Wilkins, Elicia Penuel, Bei Wang, Shweta Vadhavkar, Kun Peng, Junning Cao, Zhiming Li, Ye Zhang, Wenjin Li, Donghang Li, Mingzhu Zhou, Michael C. Wei, Antonia Kwan, Rong Zhao, Chunze Li, Chi‐Chung Li, David C. Turner   +18 more
wiley   +1 more source