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Generation and functional evaluation of bispecific T cell engaging antibodies

T cell engagers (TCE) are a class of bispecific antibodies that simultaneously target a tumor antigen and CD3, acting as a bridge between T cells and tumor cells. They promote the formation of T cell receptor (TCR)-independent canonical immune synapses and potent tumor-specific cytotoxic responses at extremely low concentrations.
Antonio, Tapia-Galisteo   +2 more
openaire   +2 more sources

Bispecific T cell engagers

2021
KAROW MARGARET   +2 more
openaire   +4 more sources

Tetracyclines Enhance Anti-tumor T-Cell Responses Induced by a Bispecific T-Cell Engager

Biological and Pharmaceutical Bulletin, 2022
Yuki Noguchi   +2 more
exaly  

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