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Generation and functional evaluation of bispecific T cell engaging antibodies
T cell engagers (TCE) are a class of bispecific antibodies that simultaneously target a tumor antigen and CD3, acting as a bridge between T cells and tumor cells. They promote the formation of T cell receptor (TCR)-independent canonical immune synapses and potent tumor-specific cytotoxic responses at extremely low concentrations.Antonio, Tapia-Galisteo +2 more
openaire +2 more sources
The expanding success of T cell-engaging bispecific antibodies
Nature Cancer, 2023openaire +2 more sources
A PD-L1xCD3 bispecific nanobody as a novel T-cell engager in treating PD-L1 overexpression melanoma
Molecular Immunology, 2023Fuqiu Li
exaly
Tetracyclines Enhance Anti-tumor T-Cell Responses Induced by a Bispecific T-Cell Engager
Biological and Pharmaceutical Bulletin, 2022Yuki Noguchi +2 more
exaly

