Results 1 to 10 of about 4,779 (180)

Bisphosphonate Associated Osteonecrosis of the Jaw: An Update on Pathophysiology, Risk Factors, and Treatment [PDF]

International Journal of Dentistry, 2014
Osteonecrosis of the jaw in patients treated with bisphosphonates is a relatively rare but well known complication at maxillofacial units around the world. It has been speculated that the medication, especially long-term i.v.
Lars Rasmusson, Jahan Abtahi
doaj   +2 more sources

Artificial Intelligence-Driven Precision Bisphosphonate Therapy in Osteoporosis: Mechanisms, Clinical Applications, Risks, and Future Directions. [PDF]

Orthop Surg
This comprehensive review integrates 17 benchmark studies to illustrate the transition of osteoporosis management toward precision medicine. The schematic highlights three key clinical applications: AI‐driven opportunistic screening from routine CTs, precision pharmacotherapy selection, and the predictive prevention of adverse events like MRONJ ...
Yao X, Chao Y, Gu X, Peng J, Yuan J, Shi W, Zhang F, Bao Q.   +7 more
europepmc   +2 more sources

Fragility fracture, atypical femoral fracture, and osteonecrosis of jaw after bisphosphonate prescription for three and five years, based on primary and secondary care data in England: nested case-control and cohort studies [PDF]

BMJ Medicine
Objectives To evaluate the association between fragility fracture and interruption of bisphosphonate prescription after three and five years of initial prescription, and to explore the incidence of atypical femoral fracture and osteonecrosis of jaw after
Victoria Welsh, Sara Muller, Tricia McKeever   +2 more
doaj   +2 more sources

Clinical Experience with Spiramycin in Bisphosphonate-Associated Osteonecrosis of the Jaw

International Journal of Immunopathology and Pharmacology, 2010
Bisphosphonate-related osteonecrosis of the jaw (BRONJ) consists of an exposure of the jaw bone that persists for over 8 weeks in patients with positive history for bisphosphonates. Symptomatology is characterized by dull and ceaseless pain, and in advanced stages, the exposure of necrotic bone is evident, which is frequently associated with purulent ...
Giulio Gasparini, Alessandro Moro, S Pelo   +2 more
exaly   +3 more sources

Histopathological assessment of the preventive effect of leukocyte-platelet-rich fibrin on bisphosphonate-related osteonecrosis of the jaw following dental extraction: An animal study

Heliyon, 2023
Background: Leukocyte- and platelet-rich fibrin (L-PRF) could be considered a preventive measure in Bisphosphonate-Related Osteonecrosis of the Jaw (BRONJ).
Golnaz Tajmiri, Milad Etemadi
exaly   +3 more sources

Bisphosphonate-associated osteonecrosis of the jaw

Indian Journal of Rheumatology, 2008
I Pande
doaj   +4 more sources

Bisphosphonate Associated Osteonecrosis of the Jaw [PDF]

The Journal of Rheumatology, 2009
In 2003, the first reports describing osteonecrosis of the jaw (ONJ) in patients receiving bisphosphonates (BP) were published. These cases occurred in patients with cancer receiving high-dose intravenous BP; however, 5% of the cases were in patients with osteoporosis receiving low-dose bisphosphonate therapy.
Aliya A, Khan, George K B, Sándor, Edward, Dore, Archibald D, Morrison, Mazen, Alsahli, Faizan, Amin, Edmund, Peters, David A, Hanley, Sultan R, Chaudry, Brian, Lentle, David W, Dempster, Francis H, Glorieux, Alan J, Neville, Reena M, Talwar, Cameron M, Clokie, Majd Al, Mardini, Terri, Paul, Sundeep, Khosla, Robert G, Josse, Susan, Sutherland, David K, Lam, Robert P, Carmichael, Nick, Blanas, David, Kendler, Steven, Petak, Louis Georges, Ste-Marie, Jacques, Brown, A Wayne, Evans, Lorena, Rios, Juliet E, Compston   +29 more
openaire   +4 more sources

Medication-related osteonecrosis of the jaw. Introduction of a new modified experimental model [PDF]

Acta Cirúrgica Brasileira, 2016
PURPOSE : To evaluate a modified experimental model for medication-related osteonecrosis of the jaw (MRONJ) through the upper right central incisor extraction followed by intravenous bisphosphonate administration. METHODS: Forty five rats underwent the
Cláudia Curra, Camila Lopes Cardoso, Osny Ferreira Júnior, Marcos Martins Curi, Mariza Akemi Matsumoto, Bruno Cavalini Cavenago, Pâmela Letícia dos Santos, Joel Ferreira Santiago Júnior   +7 more
doaj   +1 more source

Evaluation of Jaw Osteonecrosis Following Intra-Ligament Anesthesia in Zoledronate-Treated Rats: a Histological Evaluation [PDF]

Journal of Dentistry, 2023
Statement of the Problem: One of the rare adverse effects in patients who take bisphosphonates is the osteonecrosis of the jaw in the oral cavity following any trauma such as tooth extraction.Purpose: The aim of this study is the histopathological ...
Saeed Moradi, Bibi Marjan Razavi, Siavash Moushekhian, Narges Poormahmood, Mohammad Marvi   +4 more
doaj   +1 more source

Bisphosphonate-associated osteonecrosis of the jaws

Indian Journal of Dental Research, 2012
Bisphosphonates constitute a group of drugs capable of modulating bone turnover and reduce its remodeling when an excessive resorption occurs. This is why they are indicated in a large group of bone diseases like postmenopausal osteoporosis or osteolysis associated with breast cancer or multiple myeloma.
Rajiv S Desai, Subraj J Shetty
openaire   +6 more sources