Results 21 to 30 of about 6,563 (227)

Pharmacogenetics of bisphosphonate-associated osteonecrosis of the jaw

Frontiers in Bioscience, 2011
An undesirable effect associated with bisphosphonates is osteonecrosis of the jaw (ONJ). Case reports discussed ONJ development in patients with multiple myeloma or metastatic cancers receiving bisphosphonates as palliation for malignant bone disease. No causative relationship has been unequivocally demonstrated between ONJ and bisphosphonate therapy ...
MARINI, FRANCESCA, TONELLI, PAOLO, CAVALLI, LOREDANA, CAVALLI, TIZIANA, MASI, LAURA, FALCHETTI, ALBERTO, BRANDI, MARIA LUISA   +6 more
openaire   +4 more sources

Quantitative indices for cone-beam CT assessment of Medication-Related Osteonecrosis of the Jaw – a scoping review

Saudi Dental Journal, 2023
Objectives: It is not unusual for Medication-related osteonecrosis of the jaw (MRONJ) lesions that have similar clinical presentation and staging to have dissimilar radiographic extent of disease.
Ghaidaa Badabaan, Adriana G. Creanga, Steven R. Singer, Maxine Strickland, Gayathri Subramanian   +4 more
doaj   +1 more source

Guidelines for bisphosphonate-associated osteonecrosis of the jaw [PDF]

Evidence-Based Dentistry, 2008
This guideline aimed to provide recommendations for the diagnosis of bisphosphonate-associated osteonecrosis of the jaw in both the oncology and osteoporosis patient populations, for dental and medical practitioners including dentists, oral surgeons, oral pathologists, general practitioners and internal medicine specialists.
openaire   +2 more sources

Prevalence of bisphosphonate-related osteonecrosis of the jaw-like lesions is increased in a chemotherapeutic dose-dependent manner in mice [PDF]

, 2018
Bisphosphonate-related osteonecrosis of the jaw (BRONJ) worsens oral health-related quality of life. Most BRONJ occurs in multiple myeloma or metastatic breast cancer patients treated with bisphosphonate/chemotherapeutic combination therapies ...
Muneteru Sasaki, Sawase, Takashi, Kazunori Nakajima, Hayano, Hiroki, Kuroshima, Shinichiro, Nakajima, Kazunori, Takashi Sawase, Hiroki Hayano, Shinichiro Kuroshima, Saki Tamaki, Sasaki, Muneteru, Tamaki, Saki   +11 more
core   +1 more source

Novel modified quantitative index for cone-beam CT assessment of medication-related osteonecrosis of the jaw - comparative analysis with original index

Saudi Dental Journal, 2023
Purpose: The main research goal was to address the critical need for an objective and quantitative index to describe the nature and extent of radiographic features of medication-related osteonecrosis of the jaw (MRONJ) lesions and complement the ...
Ghaidaa Badabaan, Maxine Strickland, Steven R Singer, Adriana G. Creanga, Gayathri Subramanian   +4 more
doaj   +1 more source

Imaging Findings of Bisphosphonate-Associated Osteonecrosis of the Jaws [PDF]

American Journal of Neuroradiology, 2007
Bisphosphonates are drugs that decrease bone turnover by inhibiting osteoclast activity. An association between the use of bisphosphonates and osteonecrosis of the maxilla and mandible has recently been described. This study describes the imaging findings of bisphosphonate-associated osteonecrosis of the jaws.This is a retrospective series of 15 ...
P M, Phal, R W T, Myall, L A, Assael, J L, Weissman   +3 more
openaire   +2 more sources

Systematic review of the clinical effectiveness and cost-effectiveness, and economic evaluation, of denosumab for the treatment of bone metastases from solid tumours [PDF]

, 2013
Peer ...
Cummins, E., Cummins, E, R Johnston, Jones, R, Todd, R, Royle, P., Ford, J, Royle, P, F Stewart, Elders, A, E Cummins, Mowatt, G., J Ford, Todd, R., A Elders, Mowatt, G, Mulatero, C., P Royle, P Sharma, R Jones, Sharma, P., Elders, A., R Todd, Stewart, F, Mulatero, C, G Mowatt, Ford, J., Stewart, F., Sharma, P, C Mulatero, Johnston, R, Johnston, R., Jones, R.   +32 more
core   +1 more source

A Case Report of Ibandronic Acid Induced Non-Exposed BRONJ Involving the Maxillary Sinus

eJournal of Oral Maxillofacial Research, 2023
Background: The aim of this case report is to present an interesting case of bisphosphonate-related osteonecrosis of the jaw, involving the maxilla and the maxillary sinus, as a result of per os administration of ibandronic acid.
Ioannis Fotopoulos, Vasileios Zisis, Theodoros Lillis, Petros Mourouzis, Dimitrios Andreadis, Athanasios Poulopoulos, Nikolaos Dabarakis   +6 more
doaj   +1 more source

Emerging therapies with potential risks of medicine-related osteonecrosis of the jaw: a review of the literature

, 2020
In the past, osteonecrosis of the jaw (ONJ) was generally reported with bisphosphonate drugs; hence, the term BRONJ (bisphosphonate-related osteonecrosis of the jaw) was initially proposed.
Bakr, Mahmoud M, Meer, Mohammed, Allauddin Siddiqi, Mahmoud M. Bakr, Nupur Kanwar, Mohammed Meer, Kanwar, Nupur, Siddiqi, Allauddin   +7 more
core   +1 more source

Dental complications and management of patients on bisphosphonate therapy: A review article

Journal of Oral Biology and Craniofacial Research, 2013
Bisphosphonates are group of drugs that inhibit bone resorption and are used to treat a range of pathologies including Paget's disease, osteoporosis, multiple myeloma and metastasis associated with breast or prostate cancer.
Sandeep Kalra, Veena Jain
doaj   +1 more source