eJournal of Oral Maxillofacial Research, 2017 Objectives: Osteonecrosis of the jaws is a side effect associated with the use of bisphosphonates. Using histologic analysis, this study aimed to evaluate the influence of microbial colonies in the development of osteonecrosis in the jaws of rats ...
Felipe M. Silveira +3 more
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Pharmacogenetics of bisphosphonate-associated osteonecrosis of the jaw
Frontiers in Bioscience, 2011 An undesirable effect associated with bisphosphonates is osteonecrosis of the jaw (ONJ). Case reports discussed ONJ development in patients with multiple myeloma or metastatic cancers receiving bisphosphonates as palliation for malignant bone disease. No causative relationship has been unequivocally demonstrated between ONJ and bisphosphonate therapy ...
MARINI, FRANCESCA +6 more
openaire +4 more sources
Fatal infectious encephalitis as a complication of medication-related osteonecrosis of the jaw
Oral and Maxillofacial Surgery Cases, 2020 We present a unique case of bacterial encephalitis in a 79-year-old female due to progression of medication-related osteonecrosis of the jaw. The occurrence of this life-threatening neurologic condition following the expansion of medication-related ...
Hye-Won Kim +3 more
doaj +1 more source
Review and Update of the Risk Factors and Prevention of Antiresorptive-Related Osteonecrosis of the Jaw [PDF]
Endocrinology and Metabolism, 2021 Antiresorptive-related osteonecrosis of the jaw (ARONJ) is a rare but serious adverse event of bisphosphonate or denosumab administration; it is associated with severe pain and a deteriorated quality of life.
Ha Young Kim
doaj +1 more source
Prevalence of bisphosphonate-related osteonecrosis of the jaw-like lesions is increased in a chemotherapeutic dose-dependent manner in mice [PDF]
, 2018 Bisphosphonate-related osteonecrosis of the jaw (BRONJ) worsens oral health-related quality of life. Most BRONJ occurs in multiple myeloma or metastatic breast cancer patients treated with bisphosphonate/chemotherapeutic combination therapies ...
Muneteru Sasaki +11 more
core +1 more source
Imaging Findings of Bisphosphonate-Associated Osteonecrosis of the Jaws [PDF]
American Journal of Neuroradiology, 2007 Bisphosphonates are drugs that decrease bone turnover by inhibiting osteoclast activity. An association between the use of bisphosphonates and osteonecrosis of the maxilla and mandible has recently been described. This study describes the imaging findings of bisphosphonate-associated osteonecrosis of the jaws.This is a retrospective series of 15 ...
P M, Phal +3 more
openaire +2 more sources
Saudi Dental Journal, 2023 Objectives: It is not unusual for Medication-related osteonecrosis of the jaw (MRONJ) lesions that have similar clinical presentation and staging to have dissimilar radiographic extent of disease.
Ghaidaa Badabaan +4 more
doaj +1 more source
Systematic review of the clinical effectiveness and cost-effectiveness, and economic evaluation, of denosumab for the treatment of bone metastases from solid tumours [PDF]
, 2013 Peer ...
Cummins, E. +32 more
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, 2020 In the past, osteonecrosis of the jaw (ONJ) was generally reported with bisphosphonate drugs; hence, the term BRONJ (bisphosphonate-related osteonecrosis of the jaw) was initially proposed.
Bakr, Mahmoud M +7 more
core +1 more source
Dental complications and management of patients on bisphosphonate therapy: A review article
Journal of Oral Biology and Craniofacial Research, 2013 Bisphosphonates are group of drugs that inhibit bone resorption and are used to treat a range of pathologies including Paget's disease, osteoporosis, multiple myeloma and metastasis associated with breast or prostate cancer.
Sandeep Kalra, Veena Jain
doaj +1 more source