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Medication-related osteonecrosis of the jaw. Introduction of a new modified experimental model [PDF]
PURPOSE : To evaluate a modified experimental model for medication-related osteonecrosis of the jaw (MRONJ) through the upper right central incisor extraction followed by intravenous bisphosphonate administration. METHODS: Forty five rats underwent the
Cláudia Curra +7 more
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Bisphosphonate-associated osteonecrosis of the jaws
Bisphosphonates constitute a group of drugs capable of modulating bone turnover and reduce its remodeling when an excessive resorption occurs. This is why they are indicated in a large group of bone diseases like postmenopausal osteoporosis or osteolysis associated with breast cancer or multiple myeloma.
Rajiv S Desai, Subraj J Shetty
openaire +6 more sources
Pharmacogenetics of Bisphosphonate-associated Osteonecrosis of the Jaw [PDF]
Osteonecrosis of the jaws (ONJ) is a potentially severe disorder that develops in a subgroup of individuals who have used bisphosphonate (BP) medications. Several clinical risk factors have been associated with the risk of ONJ development, but evidence is limited and in most instances ONJ remains an unpredictable adverse drug reaction.
Fung, PL +4 more
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Bisphosphonate related osteonecrosis of the jaw (BRONJ) can occur in patients affected by malignancy associated hypercalcemia, bone metastases of solid tumors or multiple myeloma intaking amino-bisphosphonates or other bone resorption inhibitors.
A. Massaria +3 more
doaj +1 more source
Okawa et al. evaluate a fluorescent risedronate analogue, 800CW-pRIS, as a potential treatment for medication-related osteonecrosis of the jaw. The authors demonstrate an improvement in wound healing and inflammation with 800CW-pRIS pre-treatment in a ...
Hiroko Okawa +11 more
doaj +1 more source
Review and Update of the Risk Factors and Prevention of Antiresorptive-Related Osteonecrosis of the Jaw [PDF]
Antiresorptive-related osteonecrosis of the jaw (ARONJ) is a rare but serious adverse event of bisphosphonate or denosumab administration; it is associated with severe pain and a deteriorated quality of life.
Ha Young Kim
doaj +1 more source
Mandibular Osteonecrosis Associated with Antacid Therapy (Esomeprazole)
Introduction: Osteonecrosis of the jaw has been consistently reported in the literature associated to the high-dose intravenous bisphosphonate therapy. However, osteonecrosis can also occur in patients who have other risk factors.
Simone Marconcini +4 more
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Dental Implant Placement in Patients on Bisphosphonate Therapy: a Systematic Review
Objectives: The review aims to study dental implant placement purposefulness for patients who have been treated or are on treatment with bisphosphonate medication.
Rokas Gelazius +4 more
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Objectives: Osteonecrosis of the jaws is a side effect associated with the use of bisphosphonates. Using histologic analysis, this study aimed to evaluate the influence of microbial colonies in the development of osteonecrosis in the jaws of rats ...
Felipe M. Silveira +3 more
doaj +1 more source
Fatal infectious encephalitis as a complication of medication-related osteonecrosis of the jaw
We present a unique case of bacterial encephalitis in a 79-year-old female due to progression of medication-related osteonecrosis of the jaw. The occurrence of this life-threatening neurologic condition following the expansion of medication-related ...
Hye-Won Kim +3 more
doaj +1 more source

