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Imaging modalities for drug-related osteonecrosis of the jaw (2), Overview of the position paper on medication-related osteonecrosis of the jaw and the current status of the MRONJ in Japan

Japanese Dental Science Review, 2019
Summary: Since Marx reported on osteonecrosis of the jaw caused by the injectable bisphosphonates (BPs) pamidronate and zoledronate, there have been numerous reports not only in Western countries, but in Japan as well, of bisphosphonate-related ...
Takahiko Shibahara
exaly   +3 more sources

Medication-related osteonecrosis of the jaw: Prosthodontic considerations

Japanese Dental Science Review, 2022
Medication-related osteonecrosis of the jaw (MRONJ) can be triggered by several antiresorptive and antiangiogenic medications, including bisphosphonates (BRONJ), denosumab (DRONJ), and other agents used to treat osteoporosis and metastatic bone cancer ...
Islam E Ali, Yuka I Sumita
exaly   +3 more sources

Low awareness of medication-related osteonecrosis of the jaw among dentists: a systematic review with a medical and bioethical perspective [PDF]

BMC Medical Ethics
Introduction Medication-related osteonecrosis of the Jaw (MRONJ) is a serious adverse drug reaction that can seriously affect the quality of life of patients if not promptly diagnosed and treated. To date, preventive measures have been the most effective
Martina Coppini, Sonia Arduini, Rodolfo Mauceri, Isabel Ascension Trujillo Perez, Giuseppina Campisi   +4 more
doaj   +2 more sources

Romosozumab-associated medication-related osteonecrosis of the jaw

Oral and Maxillofacial Surgery Cases, 2023
This is the first reported case of medication-related osteonecrosis of the jaw (MRONJ) resulting from the use of romosozumab, a new anti-resorptive medication that functions through inhibition of sclerostin.
Benjamin Palla, John Anderson, Michael Miloro, Sarah Moles, Nicholas Callahan   +4 more
doaj   +2 more sources

Medication-Related Osteonecrosis of the Jaw—A Continuing Issue [PDF]

Applied Sciences, 2021
Introduction: Medication-related osteonecrosis of the jaw (MRONJ) is a condition that is becoming more common in the everyday practice of both dental and maxillofacial surgeons.
Krzysztof Wróbel, Maciej Sikora, Maciej Chęciński, Maria Jas, Dariusz Chlubek   +4 more
doaj   +2 more sources

Alterations of bone proteins in medication-related osteonecrosis of the jaw. [PDF]

Eur J Oral Sci
Abstract Changes in the protein expression pattern of osteoblastic lineage cells from the alveolar bone (OLAB) during medication‐related osteonecrosis of the jaw (MRONJ) have rarely been investigated. This lack of information is partly because of the limited availability of healthy samples and the lack of human alveolar bone cell lines for research ...
Schubert A, Brockmeyer P, Kauffmann P, Wiegel J, Lautenbacher F, Miosge N, Schminke B.   +6 more
europepmc   +2 more sources

MicroRNA in medication related osteonecrosis of the jaw: a review

Frontiers in Physiology, 2023
Medication related osteonecrosis of the jaw (MRONJ) is a condition caused by inhibition of the osteoclast activity by the anti-resorptive and anti-angiogenic drugs.
Siti Salmiah Mohd Yunus, Hui Yuh Soh, Mariati Abdul Rahman, Xin Peng, Chuanbin Guo, Roszalina Ramli   +5 more
doaj   +3 more sources

Mechanisms Underlying Medication-Related Osteonecrosis of the Jaw. [PDF]

Oral Dis
ABSTRACT Objective Medication‐related osteonecrosis of the jaw (MRONJ) is a rare but debilitating disease characterized by a progressive necrosis of jaw bones in patients who have received anti‐resorptive or anti‐angiogenic therapies.
Lee K, Kim K, Kim JY, Kim JW, Kang YH, Kim YH, Kim SJ.   +6 more
europepmc   +3 more sources

Validity of International Classification of Diseases (ICD)-9 and ICD-10 Codes for Medication-Related Osteonecrosis of the Jaw (MRONJ) Among Individuals Prescribed Antiresorptives for Fracture Prevention Across Two Cohorts [PDF]

Clinical Epidemiology
Laura D Carbone,1,2 Brian Le,3 Rachel E Elam,1,2 Emily Budde,1 Zhiping Huo,1 Dezon Finch,1 Thomas B Dodson,4 Peter J Gerngross,5 Howard A Fink,6 Robert A Adler,7 Frances Weaver,1 Joan C Lo,8 Joshua Barzilay,9,10 Laura Grangaard Johnson,11 John T ...
Carbone LD, Le B, Elam RE, Budde E, Huo Z, Finch D, Dodson TB, Gerngross PJ, Fink HA, Adler RA, Weaver F, Lo JC, Barzilay J, Grangaard Johnson L, Schousboe JT   +14 more
doaj   +2 more sources

Combined approach to treatment of advanced stages of medication-related osteonecrosis of the jaw patients

Brazilian Journal of Otorhinolaryngology, 2022
Introduction: Increased incidence of localized osteonecrosis in the jaw bones caused by bisphosphanate use and reduced quality of life of the patients led researchers to diagnose the disease in the early period and to investigate the effective treatment ...
Onur Şahin, Ender Akan, Birkan Tatar, Ceren Ekmekcioğlu, Nuri Ünal, Onur Odabaşı   +5 more
doaj   +1 more source