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Dentistry Journal, 2021 Medication-related osteonecrosis of the jaw (MRONJ) frequently affects patients after treatments with bisphosphonates or denosumab, especially with high doses in patients with bone osteoporosis, neoplastic metastases, or possibly anti-angiogenic ...
Antonio Cortese +3 more
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Local delivery of hydrogel encapsulated vascular endothelial growth factor for the prevention of medication-related osteonecrosis of the jaw [PDF]
, 2021 The anti-angiogenic effects of bisphosphonates have been hypothesized as one of the major etiologic factors in the development of medication-related osteonecrosis of the jaw (MRONJ), a severe debilitating condition with limited treatment options.
Petcu, Eugen Bogdan +5 more
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The Prevention of Medication-related Osteonecrosis of the Jaw [PDF]
Deutsches Ärzteblatt international, 2017 Medication-related osteonecrosis of the jaw (MRONJ) is a preventable complication of antiresorptive treatment. It arises in 1-20% of patients with bone metastases of solid tumors and hematologic malignancies and in 0.1-2% of patients being treated for osteoporosis with bisphosphonates. Depending on the underlying disease and medication dosage, the risk
Poxleitner, Philipp +3 more
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Clinical Case Reports, 2023 Key Clinical Message Chronic use of bisphosphonates, in combination with immunosuppressive therapy, increases the risk of jaw osteonecrosis. When sepsis occurs in patients receiving bisphosphonate, osteonecrosis of the jaw should be considered a ...
Kazuhiko Iwasaki, Akihito Okazaki
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Fatal infectious encephalitis as a complication of medication-related osteonecrosis of the jaw
Oral and Maxillofacial Surgery Cases, 2020 We present a unique case of bacterial encephalitis in a 79-year-old female due to progression of medication-related osteonecrosis of the jaw. The occurrence of this life-threatening neurologic condition following the expansion of medication-related ...
Hye-Won Kim +3 more
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The Use of Photodynamic Therapy on Medication-Related Osteonecrosis of the Jaws: Animal Study
Balkan Journal of Dental Medicine, 2021 Background/Aim: Bisphosphonate-related osteonecrosis of the jaw (BRONJ) was first introduced in 2003 and its scope was expanded by the name medication-related osteonecrosis of the jaw (MRONJ), since 2014.
Karapinar Gökay +3 more
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Osteonecrosis of The Jaw; Medication- Related Osteonecrosis of the jaw (MRONJ)
SONDE (Sound of Dentistry), 2021 Sejak tahun 2004, dilaporkan terjadinya osteonecrosis of the jaw pada pasien osteoporosis yang mengkonsumsi bifosfonat, walaupun hal tersebut lebih sedikir dibandingkan kejadian osteonecrosis of the jaw pada penderita kanker yang mendapat terapi bifosfonat secara intravena.
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Japanese Dental Science Review, 2019 Summary: Generally, CT and MR images of antiresorptive agent-related osteonecrosis of the jaw (ARONJ)/medication-related osteonecrosis of the jaw (MRONJ) show nonspecific findings as seen in active osteomyelitis．However, there are some characteristics as
Akira Baba +6 more
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Medication-related osteonecrosis of the jaw: An update
National Journal of Maxillofacial Surgery, 2022 Antiresorptive medications, such as bisphosphonates and denosumab, are an important class of medication used to treat a wide range of diseases from osteoporosis to multiple myeloma. Unfortunately, they are also associated with a rare but devastating side effect - medication-related osteonecrosis of the jaw (MRONJ). First reported in 2003, much research
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Plasma Therapy for Medication-Related Osteonecrosis of the Jaws- A Case Report
Case Reports in Clinical Practice, 2023 Medication-related osteonecrosis of the jaw (MRONJ) is a side effect of anti-bone resorption medications. Nowadays antiresorptive medications like bisphosphonate and monoclonal antibodies like denosumab that have been prescribed for bone disorders and ...
Maryam Jalili Sadrabad, Elham Saberian
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