Results 101 to 110 of about 67,063 (322)

Increased fracture rate in women with breast cancer: a review of the hidden risk

open access: yesBMC Cancer, 2011
Background Women with breast cancer, particularly individuals diagnosed at a relatively early age, have an increased incidence of fractures. Fractures can have serious clinical consequences including the need for major surgery, increased morbidity and ...
Body Jean-Jacques
doaj   +1 more source

What do we know about atypical femoral fractures? Insights and enigmas [PDF]

open access: yes, 2011
Although the existence of atypical femoral fractures is well established and bisphosphonate therapy is thought to be a major risk factor, the underlying mechanisms are poorly understood.
B. Cortet, M. Audran, T. Thomas
core   +4 more sources

Predicting peri‐implantitis incidence and implant failure via risk‐assessment and prognostication tools: A validation study

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Identifying individuals at high risk for developing peri‐implantitis (PI) and then determining the prognosis for implants with PI is crucial for treatment planning. Methods This study longitudinally followed implants from implant placement retrospectively.
Muhammad H. A. Saleh   +9 more
wiley   +1 more source

Impact of Denosumab Adherence on Renal Function and Mortality Rates in Type 2 Diabetes Patients With Osteoporosis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Type 2 diabetes mellitus (T2DM) is associated with an increased risk of osteoporosis and fractures, and denosumab, a non‐kidney‐excreted antiresorptive medication, represents a viable alternative to bisphosphonates for osteoporosis treatment in patients with T2DM. This study aimed to investigate the association among denosumab adherence, renal
Yu‐Chuan Chang   +7 more
wiley   +1 more source

The Contribution of Cholesterol and Squalene Synthase in Cancer: Molecular Mechanisms, Lipid Rafts and Therapeutic Approaches

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT A plethora of cellular signaling pathways are dysregulated in cancer cells, promoting carcinogenesis and migration. Cholesterol has recently been linked to cancer by several subcellular mechanisms, especially by its involvement in the formation of lipid rafts, which promote oncogenic signaling and cancer cell invasion. Squalene synthase (SQS),
Danai Mavridi   +2 more
wiley   +1 more source

Spectrum of activity and mechanisms of azole–bisphosphonate synergy in pathogenic Candida

open access: yesMicrobiology Spectrum
Candidiasis places a significant burden on human health and can range from common superficial vulvovaginal and oral infections to invasive diseases with high mortality.
Aidan Kane   +5 more
doaj   +1 more source

Successful control of recurrent angiosarcoma in the external auditory canal with CyberKnife radiosurgery and bisphosphonate risedronate sodium

open access: yesDermatologica Sinica, 2015
Angiosarcoma (AS) is a highly aggressive vascular tumor that spreads widely throughout the skin. Since AS tends to recur locally and metastasize early, an additional intensive therapy is necessary.
Eimei Iwama   +5 more
doaj   +1 more source

Clinical practice guidelines for the diagnosis and treatment of osteoporosis secondary to ankylosing spondylitis

open access: yesRheumatology &Autoimmunity, EarlyView.
Ankylosing spondylitis (AS) is a chronic inflammatory disease that primarily affects the axial skeleton and is often associated with secondary osteoporosis. Currently, there are no established international consensus or guidelines for managing AS‐related osteoporosis (AS‐OP). This guideline was jointly developed by several Chinese academic institutions,
Yasong Li   +23 more
wiley   +1 more source

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