Results 271 to 280 of about 67,063 (322)

Lipid Nanoparticles for Delivery of CRISPR Gene Editing Components

Small Methods, Volume 10, Issue 2, 22 January 2026.
The review presents a comprehensive overview of each component of lipid nanoparticles（LNPs）and their effects on editing efficiency. It specifically highlights strategies for achieving non‐liver delivery, aiming for broader applications in gene editing. Furthermore, this review summarizes the applications of LNPs in gene editing and offers insights for ...
Fan Wu, Nei Li, Yudian Xiao, Rohan Palanki, Hannah Yamagata, Michael J. Mitchell, Xuexiang Han   +6 more
wiley   +1 more source

Baseline Characteristics of the TOPaZ Study: Randomised Trial of Teriparatide and Zoledronic Acid Compared with Standard Care in Adults with Osteogenesis Imperfecta. [PDF]

Calcif Tissue Int
Hald JD, Weir C, Keerie C, Dewar L, MacLean M, Milne L, Keen R, Walsh J, Poole K, Langdahl B, Lindsay JR, Ghouri N, Hollick RJ, Aspray T, Crowley RK, Cohen-Solal M, Hassan-Smith Z, Tuck S, Curtis E, Harvey N, Eekhoff EMW, Feenstra J, Hampson G, Stone M, Turton J, Patel P, Siddiqi M, Munro R, Roy M, Paskins Z, Narayanan D, Malcolm E, Javaid MK, Osborne P, Tang JCY, Lam W, Moore D, Black HA, Duckworth AD, Makaram N, Guo T, Stenhouse G, Ralston SH.   +42 more
europepmc   +1 more source

Lymph Node‐Targeted Nanomaterials for Controlled Nano‐Immunotherapy

Small Structures, Volume 7, Issue 1, January 2026.
This study primarily investigates lymph node‐targeted immunotherapeutic strategies, focusing on the mechanisms of immune response regulation within lymph nodes. By targeting distinct immune signaling pathways, we systematically explore the development of nanodrug delivery systems specifically designed for lymph node targeting to achieve enhanced ...
Yitong Zhao, Mengjun Wang, Ming Ma, Yu Zhang, Haoan Wu   +4 more
wiley   +1 more source

Serum miR-146a as a diagnostic and predictive biomarker for osteoporosis and bisphosphonate treatment efficacy. [PDF]

Am J Transl Res
Yin Q, Yang R, Yu H.
europepmc   +1 more source

Adjuvant pharmacological strategies for the musculoskeletal system during long‐term space missions

British Journal of Clinical Pharmacology, Volume 92, Issue 1, Page 11-23, January 2026.
Abstract Despite 2 h of daily exercise training, muscle wasting and bone loss are still present after 6‐month missions to the international space station. Some crew members lose bone much faster than others. In preparation for missions to the Moon and Mars, space agencies are therefore reviewing their countermeasure portfolios.
Friederike Thomasius, Dominik Pesta, Jörn Rittweger   +2 more
wiley   +1 more source

Dual Growth Factor Release From Collagen Based Multilayer Films on Ti‐Surfaces Enhances Periimplant Bone Formation and Angiogenic Activity—An Experimental In‐Vivo Study

Clinical Oral Implants Research, Volume 37, Issue 1, Page 1-17, January 2026.
ABSTRACT Objectives The aim of the present study was to assess the effect of dual growth factor release from collagen‐based polyelectrolyte multilayer films (PEMs) on titanium implants on periimplant bone formation and angiogenetic activity in minipig mandibles.
Philipp Kauffmann, Susanne Wolfer, Christina Behrens, Pauline Schlosser, Christian Dullin, Uwe Schirmer, Klaus Liefeith, Henning Schliephake   +7 more
wiley   +1 more source

Adrenal Crisis Induced by Zoledronic Acid in Two Patients With Hypopituitarism: A Case Report and Literature Review. [PDF]

Case Rep Endocrinol
AlFaifi AM, AlMistehi WM.
europepmc   +1 more source

Cross‐Linked Volume‐Stable Collagen Matrix Versus Connective Tissue Graft for Soft Tissue Augmentation at Implant Site. A Non‐Inferiority, Multicenter Randomized Clinical Trial

Clinical Oral Implants Research, Volume 37, Issue 1, Page 45-56, January 2026.
ABSTRACT Aims To compare the efficacy of cross‐linked volume‐stable collagen matrix (VCMX) versus connective tissue graft (CTG) to increase buccal peri‐implant mucosal thickness (MT) around dental implants. Methods The present is a parallel, randomized multi‐center clinical trial, according to the CONSORT statement.
Francesco Cairo, Cosimo Rupe, Raffaele Cavalcanti, Luca Landi, Antonio Rupe, Nicola Marco Sforza, Walter Castelluzzo, Maria Di Martino, Luigi Barbato   +8 more
wiley   +1 more source

Strategies for the Prevention of Medication-Related Osteonecrosis of the Jaw (MRONJ): An Umbrella Review. [PDF]

Cureus
Gharibi A, Essadeq Z, Yamine H, Al Jalil Z, Kissa J.   +4 more
europepmc   +1 more source

Pharmacotherapy Risks in Rare Genetic Diseases: Cross‐Referencing ACMG Secondary Findings v3.2 List With Clinical Databases

Clinical and Translational Science, Volume 19, Issue 1, January 2026.
ABSTRACT Clinical genomics and pharmacogenomics have largely remained separate fields, though some genetic variants have overlapping disease risk and drug implications. However, the extent of this overlap is not well studied. To explore this gap, we cross‐referenced genes from the American College of Medical Genetics Secondary Findings v3.2 list with ...
Josiah D. Allen, Benjamin Q. Duong, Jordan Brady, Pamela Arn   +3 more
wiley   +1 more source