Results 31 to 40 of about 94,587 (255)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
A Generalized Bit Error Rate Evaluation for Index Modulation Based OFDM System
IEEE Access, 2020 Orthogonal frequency division multiplexing (OFDM-IM) is a multicarrier transmission technology that modulates information bits not just onto subcarriers by means of M-ary constellation mapping but also onto selected (active) subcarrier indices ...
Mahmoud Abdullahi +4 more
doaj +1 more source
Bit error rate estimation for turbo decoding
IEEE Transactions on Communications, 2003 In this paper we propose a method for on-line estimation of bit error rate during turbo decoding. We model the log-likelihood ratios as a mixture of two Gaussian random variables and derive estimators for the mean and variance of these distributions based on a maximum-likelihood approach. The parameter estimates are then employed to calculate the cross-
Nick Letzepis, Alex J. Grant
openaire +2 more sources
Bit Error and Block Error Rate Training for ML-Assisted Communication
ICASSP 2023 - 2023 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP), 2023 ISBN:978-1-7281-6328 ...
Wiesmayr, Reinhard; id_orcid0000-0003-2882-7934 +4 more
openaire +3 more sources
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Asynchronous Chirp Slope Keying for Underwater Acoustic Communication
Sensors, 2021 We propose an asynchronous acoustic chirp slope keying to map short bit sequences on single or multiple bands without preamble or error correction coding on the physical layer.
Dominik Jan Schott +7 more
doaj +1 more source
A Simplified Model of Bit Error Rate Calculation
Computer and Information Science, 2015 <p>The Bit Error Rate (BER) is a key parameter of the Quality of Service (QoS) for engineers and designers of digital communication systems and networks. At the present time, a set of models and methods are exist for calculating the BER. But these methods are complex and require large computing cost.</p><p>In this paper, we provide a
Saed Ali Thuneibat +2 more
openaire +2 more sources
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source