Results 41 to 50 of about 7,168,348 (289)
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Bit error rate estimation for turbo decoding
IEEE Transactions on Communications, 2003 In this paper we propose a method for on-line estimation of bit error rate during turbo decoding. We model the log-likelihood ratios as a mixture of two Gaussian random variables and derive estimators for the mean and variance of these distributions based on a maximum-likelihood approach. The parameter estimates are then employed to calculate the cross-
Nick Letzepis, Alex J. Grant
openaire +2 more sources
The bit error performance and information transfer rate of SPAD array optical receivers [PDF]
, 2020 In this paper the photon counting characteristics, the information rate and the bit error performance of single-photon avalanche diode (SPAD) arrays are investigated.
Safari, Majid +2 more
core +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
A Simplified Model of Bit Error Rate Calculation
Computer and Information Science, 2015 <p>The Bit Error Rate (BER) is a key parameter of the Quality of Service (QoS) for engineers and designers of digital communication systems and networks. At the present time, a set of models and methods are exist for calculating the BER. But these methods are complex and require large computing cost.</p><p>In this paper, we provide a
Saed Ali Thuneibat +2 more
openaire +2 more sources
A Generalized Bit Error Rate Evaluation for Index Modulation Based OFDM System
IEEE Access, 2020 Orthogonal frequency division multiplexing (OFDM-IM) is a multicarrier transmission technology that modulates information bits not just onto subcarriers by means of M-ary constellation mapping but also onto selected (active) subcarrier indices ...
Mahmoud Abdullahi +4 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Bit Error and Block Error Rate Training for ML-Assisted Communication
ICASSP 2023 - 2023 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP), 2023 ISBN:978-1-7281-6328 ...
Wiesmayr, Reinhard; id_orcid0000-0003-2882-7934 +4 more
openaire +5 more sources
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source