Results 41 to 50 of about 94,587 (255)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Block Markov superposition transmission over turbulence channels in outdoor optical wireless communication

open access: yesTongxin xuebao, 2017
Based on the equivalent genie-aided system,the bit-error rate of the block Markov superposition transmission system was analyzed and the union bound of the bit-error rate of the genie-aided system was derived.When the bit-error rate was extremely low at ...
Jin-shun ZHU, Xiao MA
doaj   +2 more sources

Bit Error Rate Tester

open access: yes, 2015
GSI Scientific Report 2014 - GSI Report 2015 ...
Miedzik, P., Koczon, P.
openaire   +2 more sources

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Hybrid-Index Modulation in Fading Channels With Integrated Sensing and Communication

open access: yesIEEE Open Journal of Vehicular Technology
Ultra-high-speed data transfer and energy efficiency are rapidly emerging as challenging and simultaneous requirements for next-generation vehicle-to-vehicle communication networks. This paper presents the first semi-analytical bit-error-rate analysis of
Jaswinder Lota, Andreas Demosthenous
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Reconstruction of sparse check matrix for LDPC at high bit error rate

open access: yesTongxin xuebao, 2021
In order to reconstruct the sparse check matrix of LDPC, a new algorithm which could directly reconstruct the LDPC was proposed.Firstly, according to the principle of the traditional reconstruction algorithm, the defects of the traditional algorithm and ...
Zhaojun WU   +3 more
doaj   +2 more sources

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

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