Results 41 to 50 of about 843,086 (287)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Security of quantum key distribution with multiphoton components

open access: yes, 2016
Most qubit-based quantum key distribution (QKD) protocols extract the secure key merely from single-photon component of the attenuated lasers. However, with the Scarani-Acin-Ribordy-Gisin 2004 (SARG04) QKD protocol, the unconditionally secure key can be ...
Chen, Zeng-Bing   +3 more
core   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

A Novel LS/LMMSE Based PSO Approach for 3D-Channel Estimation in Rayleigh Fading

open access: yesAdvanced Electromagnetics, 2018
A high transmission rate can be obtained using Multi Input Multi Output (MIMO) Orthogonal Frequency Division Multiplexing (OFDM) model. The most commonly used 3D-pilot aided channel estimation (PACE) techniques are Least Square (LS) and Least Minimum ...
D. N. Bhange, C. Dethe
doaj   +1 more source

Bit error rate analysis of MISO FSO systems

open access: yesWaves in Random and Complex Media, 2016
AbstractMultiple-input single-output (MISO) systems are employed in free space optical (FSO) links to mitigate the degrading effects of atmospheric turbulence. In this paper, we consider a MISO FSO system with practical transmitter and receiver configuration that consists of radial laser array with Gaussian beams and a Gaussian receiver aperture ...
Gokce, Muhsin Caner   +2 more
openaire   +3 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

A Deterministic Analysis of Decimation for Sigma-Delta Quantization of Bandlimited Functions

open access: yes, 2015
We study Sigma-Delta ($\Sigma\Delta$) quantization of oversampled bandlimited functions. We prove that digitally integrating blocks of bits and then down-sampling, a process known as decimation, can efficiently encode the associated $\Sigma\Delta$ bit ...
Daubechies, Ingrid, Saab, Rayan
core   +2 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Invariance of the bit error rate in the ancilla-assisted homodyne detection

open access: yes, 2010
We investigated the minimum achievable bit error rate of discriminating binary coherent states by homodyne measurements with the help of arbitrary ancilla states coupled via beam splitters.
Sasaki, Masahide   +2 more
core   +1 more source

Home - About - Disclaimer - Privacy