Results 11 to 20 of about 344,829 (184)

Epitope Profiling of SARS-CoV-2 Spike Antigen Provides a Novel Strategy for Developing ELISAs Specific for Different Spike Protein Variants in Bivalent Vaccine Formulations

Vaccines
Background/Objectives: An initial COVID-19 candidate vaccine containing a purified ancestral SARS-CoV-2 spike antigen was characterized with an ELISA using recombinant monoclonal antibodies (mAbs) generated against this variant.
Luciano Ettorre, Trevor Williams, Camille Houy, Shaolong Zhu, Michael Kishko, Ali Azizi, Andrew D. James, Beata Gajewska, Jason Szeto   +8 more
doaj   +2 more sources

Efficacy of inactive bivalent and trivalent Streptococcus agalactiae bacteria (biotype 1 & 2) vaccines on tilapia, Oreochromis niloticus [PDF]

E3S Web of Conferences, 2021
Streptococcosis is a significant fish disease impacting tilapia culture in Indonesia, causing losses estimated up to IDR 15.0 billion annually. This study aims to assess the efficacy of bivalent and trivalent vaccines containing Streptococcus agalactiae ...
Taukhid, Lusiastuti Angela M., Andriyanto Septyan, Sugiani Desy, Sumiati Tuti, Suhermanto Achmad   +5 more
doaj   +1 more source

Efficacy of an unmodified bivalent mRNA vaccine against SARS-CoV-2 variants in female small animal models [PDF]

, 2023
Combining optimized spike (S) protein-encoding mRNA vaccines to target multiple SARS-CoV-2 variants could improve control of the COVID-19 pandemic. We compare monovalent and bivalent mRNA vaccines encoding B.1.351 (Beta) and/or B.1.617.2 (Delta) SARS-CoV-
Maione, Domenico, Wernike, Kerstin, Corleis, Björn, Mettenleiter, Thomas C., Hoffmann, Donata, Rauch, Susanne, Schön, Jacob, Fricke, Charlie, Kovacikova, Kristina, Ulrich, Lorenz, Mueller, Stefan O., Gergen, Janina, Schlottau, Kore, Halwe, Nico Joel, Roth, Nicole, Ciesek, Sandra, Petsch, Benjamin, Widera, Marek, Beer, Martin, Dorhoi, Anca, Halwe, Nico   +20 more
core   +1 more source

mRNA-1273 bivalent (original and Omicron) COVID-19 vaccine effectiveness against COVID-19 outcomes in the United States

Nature Communications, 2023
The bivalent (original and Omicron BA.4/BA.5) mRNA-1273 COVID-19 vaccine was authorized to offer broader protection against COVID-19. We conducted a matched cohort study to evaluate the effectiveness of the bivalent vaccine in preventing hospitalization ...
Hung Fu Tseng, Bradley K. Ackerson, Lina S. Sy, Julia E. Tubert, Yi Luo, Sijia Qiu, Gina S. Lee, Katia J. Bruxvoort, Jennifer H. Ku, Ana Florea, Harpreet S. Takhar, Radha Bathala, Cindy Ke Zhou, Daina B. Esposito, Morgan A. Marks, Evan J. Anderson, Carla A. Talarico, Lei Qian   +17 more
doaj   +1 more source

Immunogenicity and Efficacy of a Feed-Based Bivalent Vaccine against Streptococcosis and Motile Aeromonad Septicemia in Red Hybrid Tilapia (Oreochromis sp.)

Animals, 2023
Streptococcosis and motile Aeromonad septicemia (MAS) are the main bacterial diseases in tilapia culture worldwide, causing significant economic losses. Vaccination is an effective method of preventing diseases and contributes to economic sustainability.
Nur Shidaa Mohd Ali, Mohd Zamri Saad, Mohammad Noor Amal Azmai, Annas Salleh, Zarirah Mohamed Zulperi, Tilusha Manchanayake, Muhammad Amir Danial Zahaludin, Lukman Basri, Aslah Mohamad, Ina Salwany Md Yasin   +9 more
doaj   +1 more source

Development of a bivalent conjugate vaccine candidate against rotaviral diarrhea and tuberculosis using polysaccharide from Mycobacterium tuberculosis conjugated to ΔVP8* protein from rotavirus

, 2021
Conjugation of carbohydrate antigens with a carrier protein is a clinically proven strategy to overcome the poor immunogenicity of bacterial polysaccharide.
조상래
core   +1 more source

Development of freeze-dried bivalent fish vaccine product with skimmed milk as stabiliser [PDF]

E3S Web of Conferences, 2023
Bacterial vaccines have been tested for their effectiveness in protecting fish from potential virulent diseases. The current vaccine preparations are mostly in liquid form, which affects prices due to an increase in the cost of shipment, the stability of
Sugiani Desy, Lusiastuti Angela Mariana, Sumiati Tuti, Setiadi Setiadi, Purwaningsih Uni, Gardenia Lila, Taukhid, Murwantoko, Isnansetyo Alim, Handayani Desy Putri   +9 more
doaj   +1 more source

Immunogenicity, efficacy, and safety of human papillomavirus vaccine: Data from China

Frontiers in Immunology, 2023
The incidence rate and mortality rate of cervical cancer have steadily increased in young women in China. Therefore, it is critical to improve HPV vaccination rates, particularly for the younger population.
Mingzhu Li, Chao Zhao, Yun Zhao, Jingran Li, Lihui Wei   +4 more
doaj   +1 more source

Reduction of low- and high-grade cervical abnormalities associated with high uptake of the HPV bivalent vaccine in Scotland [PDF]

, 2014
In Scotland, a national HPV immunisation programme began in 2008 for 12-13 year olds, with a catch-up campaign from 2008-2011 for those under the age of 18.
Kavanagh, K, Cruickshank, M, Cubie, H., C Robertson, Pollock, Kevin G.J., J Love, Pollock, K G J, Potts, A., Love, J., K Kavanagh, Cruickshank, M., Nicoll, Sheila, Donaghy, Martin, Palmer, Tim J, K Cuschieri, Robertson, C, Palmer, T J, M Donaghy, Cuschieri, K., Robertson, C., H, Cubie,, Potts, Alison, H Cubie, M Cruickshank, Nicoll, S., Donaghy, M, Pollock, K. G. J., Potts, A, Love, John, Cuschieri, Kate, Kavanagh, K., Donaghy, M., S Nicoll, Cuschieri, K, Cubie, H, Nicoll, S, Cruickshank, Maggie, T J Palmer, Love, J, Kavanagh, Kimberley, K G J Pollock, Robertson, Chris, Palmer, T. J., A Potts   +43 more
core   +1 more source

Comparing the effectiveness of bivalent and monovalent COVID-19 vaccines against COVID-19 infection during the winter season of 2022-2023: A real-world retrospective observational matched cohort study in the Republic of Korea

International Journal of Infectious Diseases, 2023
Objectives: To compare the effectiveness of bivalent and monovalent COVID-19 vaccines throughout the 2022-2023 winter season based on real-world data. Methods: This retrospective observational matched cohort study used the national vaccination program ...
Chungman Chae, Ryu Kyung Kim, Eun Jung Jang, Ji Ae Shim, Eunkyung Park, Kil Hun Lee, Sye Lim Hong, Asma Binte Aziz, Birkneh Tilahun Tadesse, Florian Marks, Sangwoo Tak, Sangwon Lee, Donghyok Kwon   +12 more
doaj   +1 more source