Results 61 to 70 of about 344,829 (184)

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

Antibody Response to the BA.5 Bivalent Vaccine Shot: a Two-Year Follow-Up Study following Initial COVID-19 mRNA Vaccination

Microbiology Spectrum, 2023
Although many studies have been conducted on the increase in spike antibody levels after vaccination, there is insufficient prospective and longitudinal information on the BA.5-adapted bivalent vaccine up to the fifth vaccination.
Yosuke Hirotsu, Hiroki Sugiura, Mika Takatori, Hitoshi Mochizuki, Masao Omata   +4 more
doaj   +1 more source

Neutralizing antibodies respond to a bivalent dengue DNA vaccine or/and a recombinant bivalent antigen

Molecular Medicine Reports, 2014
There is currently no effective vaccine to prevent dengue infection, despite the existence of multiple studies on potential methods of immunization. The aim of the present study was to explore the effect of DNA and/or recombinant protein on levels of neutralizing antibodies.
Zhi-Shan, Zhang, Yu-Wei, Weng, Hai-Long, Huang, Jian-Ming, Zhang, Yan-Sheng, Yan   +4 more
openaire   +3 more sources

Characterization and immunogenicity of nanoparticle vaccines displaying embecovirus spike proteins

Biotechnology Progress, EarlyView.
Virus‐like particle vaccines displaying spike proteins from OC43, HKU1 A, and HKU1 B were evaluated in mice for their ability to elicit antibodies against the spike proteins from OC43, HKU1 A, HKU1 B, and HKU1 C. Abstract Endemic human coronaviruses OC43 and HKU1 cause widespread respiratory infections and can be associated with severe illness in ...
Peter J. Halfmann, Augustine Duffy, Alex Wee, Noah Anderson, Jackson Terrell, Yoshihiro Kawaoka, Ravi S. Kane   +6 more
wiley   +1 more source

Preclinical evaluation of a bivalent conjugate vaccine against Salmonella Typhi and Paratyphi A

Frontiers in Immunology
IntroductionSalmonella enterica serovars Typhi and Paratyphi A cause millions of cases and thousands of deaths annually, predominantly affecting children in South and Southeast Asia.
Renzo Alfini, Roberta Di Benedetto, Martina Carducci, Vikram Paradkar, Hanuman Mallubhotla, Santosh Renukuntla, Dharmeshkumar Patel, Senthilkumar Manoharan, Mallikarjuna Panchakshari, Mahesh Kyasani, Nupur Sengupta, Laura B. Martin, Omar Rossi, Simona Rondini, Carlo Giannelli, Francesca Micoli   +15 more
doaj   +1 more source

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source

A 5-year follow-up of antibody response in children vaccinated with single dose of live attenuated SA14-14-2 Japanese encephalitis vaccine: immunogenicity and anamnestic responses

, 2008
Out of 98 subjects who had participated in the 2000 JE vaccination campaign, 69 people were enrolled in the tests of 2004 and 2005 for the evaluation of long term immune response of a single dose of live attenuated SA14-14-2 JE vaccine.
오희철
core   +1 more source

Occupational HPV Exposure in Otolaryngology: A Scoping Review of Detection, Risk, and Prevention

The Laryngoscope, EarlyView.
This scoping review identified 10 studies evaluating occupational HPV exposure in otolaryngology. HPV DNA was detected in surgical plume following some HPV‐related procedures, including up to 56.7% of CO2 laser plume samples, while the only study assessing oral HPV among exposed clinicians reported a prevalence of 2.2%, not exceeding that of the ...
Ying Jie Li, Alexander C. Moise, Amanda Hu   +2 more
wiley   +1 more source

Selection and characterization of vaccine strain for Enterovirus 71 vaccine development

, 2012
[[abstract]]Enterovirus 71 (EV71) has recently emerged as an important neurotropic virus in Asia because effective medications and prophylactic vaccine against EV71 infection are not available.
Chang, JY;Chang, CP;Tsai, HH;Lee, CD;Lian, WC;Ih Jen, S;Sai, IH;Liu, CC;Chou, AH;Lu, YJ;Chen, CY;Lee, PH;Chiang, JR;Chong, PC
core   +1 more source

A Bivalent Meningococcal B Vaccine in Adolescents and Young Adults

New England Journal of Medicine, 2017
MenB-FHbp is a licensed meningococcal B vaccine targeting factor H-binding protein. Two phase 3 studies assessed the safety of the vaccine and its immunogenicity against diverse strains of group B meningococcus.We randomly assigned 3596 adolescents (10 to 18 years of age) to receive MenB-FHbp or hepatitis A virus vaccine and saline and assigned 3304 ...
Ostergaard L, Vesikari T, Absalon J, Beeslaar J, Ward BJ, Senders S, Eiden JJ, Jansen KU, Anderson AS, York LJ, Jones TR, Harris SL, O'Neill R, Radley D1, Maansson R1, Prégaldien JL1, Ginis J1, Staerke NB1, Perez JL1, B1971009 and B1971016 Trial Investigators. Belle-Isle J, Elfassi E, Fredette P, Garfield H, Girard G, Lachance P, Adamkova E, Bartonova E, Drazan D, Dvorakova J, Kosina P, Kyjonkova A, Ruzkova R, Vitousova E, Ahonen A, Forsten A, Karppa T, Kokko S, Lagerstrom-Tirri PM, Simila JK, Adelt T, Behre U, Schwarz TF, Castiglia P, Esposito S, Ferrera G, Icardi G, Brzostek J, Hasiec B, Konior R, Pejcz J, Szymanski H, Witor A, Faust SN, Finn AH, Heath PT, Pollard AJ, Altamirano DD, Ashley CT Jr, Bader GF, Bauer GH Jr, Block SL Jr, Brandon DM, Davis MG, DeValle O, Egelhof RH, Essink BJ, Fouch BB, Fox BP, Franklin ER, Garscadden AG, Goswami UP, Gregory DM, Helman LL, Houchin VG, Howard CE, Johnson AD, Johnston WH Jr, Jordan CA, Kimmel MA, Klein TR, Krilov LR, LaBarbera AP, Labuda JM II, Latiolais TG, Lello LG, Lewis DH, Ley JA, London AL, Martin MS, McGuire MR, Mosteller VC, Naccarato TR, Nassim CG, Rey MR, Robbins RA, Rouse KG, Schear MJ, Senders SD, Shepard JS, Simpson MW, Slandzicki AJ, Slechta SB, Tetrick LL, Varman M, Wadsworth LT III, Ware DB, White JH, Wisman PP Jr, Blouin F, Dionne M, Dzongowski P, Heaton KJ, Langley JM, O'Mahony MFJ, Powell CN, Ward BJ, Ostergaard LJ, Haapaniemi TL, Paassilta M, Volanen IK, Lepich T, Smukalska E, Tarczon I, Tetiurka BM, Domingo JD, Morato AV, Riera MT, Sanchez CA, Torrell JMR, Blumenau J, Campbell NG, Cervantes JA, Douglas WG, Ensz DJ, Ervin JE, Fiel TC, Fragoso VG, Fried DL, Gleason GP, Green SL, Haggag AZ, Johnson CT, Khaira RS, Kirstein JL, Kravitz AE, Lederman SN, Marcadis I, Miller VE, Moretti JM, Pragalos AA, Puopolo AD, Rubino J, Seiden DJ, Sharp SC, Sheldon EA, Shockey GR, Smith WB, Stringer JC, Strout CB, Studdard HE, Tresser NJL.   +160 more
openaire   +4 more sources