Results 71 to 80 of about 344,829 (184)

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Single dose of SA 14-14-2 vaccine provides long-term protection against Japanese encephalitis: A case-control study in Nepalese children 5 years after immunization

, 2007
In July 1999, a single dose of live-attenuated SA 14-14-2 Japanese encephalitis (JE) vaccine was administered to children living in the Bardiya, Banke and Kailali districts of Nepal.
오희철, 남정모
core   +1 more source

Effectiveness of influenza vaccine in aging and older adults: comprehensive analysis of the evidence [PDF]

, 2012
Foremost amongst the diseases preventable by vaccination is influenza. Worldwide, influenza virus infection is associated with serious adverse events leading to hospitalization, debilitating complications, and death in elderly individuals ...
Assir N, Lang, Pierre-Olivier, Govind, Sheila, Aspinall R, Mendes A, Mendes, Aline, Socquet, Jennifer, Govind S, Socquet J, Assir, Noémie, Lang PO, Aspinall, Richard   +11 more
core   +1 more source

Advances in research on layered double hydroxides for biomedical applications

Smart Molecules, EarlyView.
Layered double hydroxides (LDHs) are pH‐responsive nanomaterials with broad biomedical applications. This review summarizes LDH synthesis methods and compares their advantages. It highlights LDHs' progress in cancer therapy, including chemo‐photothermal, chemo‐immunotherapy, and photodynamic‐immunotherapy combinations and their potential in bone repair.
Xinhui Yang, Zhiping Zhang, Zhao Wang, Hao Zhang, Yen Leng Pak, Yingying Jing, Yurong Guo, Fang Li, Xiao Wang, Quanxiang Han, Lei Yu, Xuejiao Li, Xing Gao, Jibin Song   +13 more
wiley   +1 more source

Safety and immunogenicity studies in animal models support clinical development of a bivalent norovirus-like particle vaccine produced in plants

, 2022
Noroviruses (NoV) are the leading cause of epidemic acute gastroenteritis in humans worldwide. A safe and effective vaccine that prevents NoV infection or minimizes NoV disease burden is needed, especially for children and the elderly who are ...
Thieme, Frank, Blazevic, Vesna, Klimyuk, Victor, Malm, Maria, Tamminen, Kirsi, Diessner, André, Jarczowski, Franziska, Tusé, Daniel   +7 more
core   +1 more source

Vaccinia Virus Vector Bivalent Norovirus Vaccine

Viruses
Norovirus is a major etiological agent of nonbacterial gastroenteritis around the world. Due to its in vitro culture complexity, high genome diversity, and the lack of cross-reactive immunity between genogroups, there is an unmet urgent need for polyvalent norovirus vaccines that provide broad-spectrum protection, and no vaccine has gained global ...
Yunbo Bai, Xi Wu, Yanru Shen, Liangliang Wang, Ziqi Cheng, Yeqing Sun, Hao Wu, Qingfeng Zhang, Ziqi Sun, Chenchen He, Binfan Liao, Weijin Huang, Huanzhang Xia   +12 more
openaire   +3 more sources

Safety of and serological response to a new canine distemper‐parvovirus combination vaccine in domestic ferrets

Veterinary Record, EarlyView.
Abstract Background Pet ferrets are typically vaccinated against distemper using a canine multivalent vaccine despite the lack of relevant safety or efficacy data. Here, we investigate the safety of a novel live canine parvovirus type 2c (CPV‐2c) vaccine strain and the efficacy of the live Onderstepoort canine distemper virus (CDV) vaccine strain used ...
Jacqueline Pearce, Léon Peeters, Ellen Versmissen, David Sutton, Ian Tarpey   +4 more
wiley   +1 more source

Bivalent Omicron BA.1 vaccine booster increases memory B cell breadth and neutralising antibodies against emerging SARS-CoV-2 variantsResearch in context

EBioMedicine
Summary: Background: Current literature informs us that bivalent vaccines will generate a broader serum neutralizing antibody response to multiple SARS-CoV-2 variants, but studies on how this breadth relates to the memory B cell (MBC) and T cell ...
Lok Bahadur Shrestha, Katie Tungatt, Anupriya Aggarwal, Aija Stubis, Nicole L. Fewings, Christina Fichter, Anouschka Akerman, Chaturaka Rodrigo, Nicodemus Tedla, Sharon Lee, Andrew R. Lloyd, Fabienne Brilot, Warwick J. Britton, Anthony Kelleher, Ian D. Caterson, Mark W. Douglas, Rebecca Rockett, Stuart G. Tangye, James A. Triccas, Stuart G. Turville, Kerrie J. Sandgren, Rowena A. Bull, Anthony L. Cunningham, Anthony L. Cunningham, Tania Sorrell, Anthony Kelleher, Warwick Britton, Mark Maclean, Sharon Lee, Joanne Camilleri, Mark Douglas, Rowena Bull, Kerrie Sandgren, Yang Song, Lijun Mao, Amy Phu, Allison Sigmund, Sophie Beard, Ian Caterson, Stephanie Hunt, Anne Marie Vande More, Rama Kandasamy, Ian Caterson, Jen Kok, Jennifer Byrne, Andrew Lloyd, James Triccas, Stuart Tangye, Stuart Turville, Fabienne Brilot, Matthew O’Sullivan, Megan Steain, Sarah Baird, Chansavath Phetsouphanh, Yanran Zhao   +54 more
doaj   +1 more source

Preclinical safety evaluation of a bivalent inactivated EV71-CA16 vaccine in mice immunized intradermally

Human Vaccines & Immunotherapeutics, 2023
Hand, foot and mouth disease is a common acute viral infectious disease that poses a serious threat to the life and health of young children. With the development of an effective inactivated EV71 vaccine, CA16 has become the main pathogen causing HFMD ...
Yun Liao, Qinfang Jiang, Xinqian Huo, Li Yu, Jinling Yang, Heng Zhao, Dandan Li, Xingli Xu, Guorun Jiang, Caixing Zhang, Cong Li, Yun Li, Ying Zhang, Mingxiang Shao, Baofeng Liu, Lianzhong Shen, Shengtao Fan, Qihan Li   +17 more
doaj   +1 more source

Nanobodies as next‐generation targeting platforms: From discovery technologies to translational biomedicine

VIEW, EarlyView.
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley   +1 more source